Search Results - "Monaghan, Laura"

The Emerging Role of H3K9me3 as a Potential Therapeutic Target in Acute Myeloid Leukemia by Monaghan, Laura, Massett, Matthew E, Bunschoten, Roderick P, Hoose, Alex, Pirvan, Petrisor-Alin, Liskamp, Robert M J, Jørgensen, Heather G, Huang, Xu

“…Growing evidence has demonstrated that epigenetic dysregulation is a common pathological feature in human cancer cells. Global alterations in the epigenetic…”
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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival by Massett, Matthew E., Monaghan, Laura, Patterson, Shaun, Mannion, Niamh, Bunschoten, Roderick P., Hoose, Alex, Marmiroli, Sandra, Liskamp, Robert M. J., Jørgensen, Heather G., Vetrie, David, Michie, Alison M., Huang, Xu

“…Epigenomic dysregulation is a common pathological feature in human hematological malignancies. H3K9me3 emerges as an important epigenomic marker in acute…”
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P433: PHARMACOLOGICAL DUAL INHIBITION OF PARP AND TIP60 AS A PROSPECTIVE THERAPEUTIC REGIMEN INDUCES SYNERGISTIC AML CELL DEATH by Ju Park, Tae, Wheadon, Helen, Monaghan, Laura, Huang, Xu, Jorgensen, Heather

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Patient Disposition and Clinical Outcome After Referral to a Dedicated TAVI Clinic by Gorecka, Miroslawa, Reddin, Catriona, Madders, Gillian, Monaghan, Laura, Neylon, Antoinette, Sharif, Faisal, Hynes, Brian, Fennelly, Evelyn, McHugh, Fiachra, Martin, Niamh, Mohammed, Khalid, Bijjam, Venu Reddy, Veerasingam, David, Soo, Alan, DaCosta, Mark, Wijns, William, Mylotte, Darren

“…Transcatheter aortic valve implantation (TAVI) is the standard of care for the majority of patients with severe symptomatic aortic stenosis (AS) at excessive-,…”
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Translation‐coupled mRNA quality control mechanisms by Monaghan, Laura, Longman, Dasa, Cáceres, Javier F

“…Abstract mRNA surveillance pathways are essential for accurate gene expression and to maintain translation homeostasis, ensuring the production of fully…”
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Synergistic Leukaemia Cell Death Induced with PARP and TiP60 Inhibitors Is a Prospective Therapeutic Strategy for AML by Park, Tae Ju, Monaghan, Laura, Copland, Mhairi, Huang, Xu, Wheadon, Helen, Jørgensen, Heather G

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Pharmacological Targeting of Kdm4a as a Potential Therapeutic Strategy in Aml by Monaghan, Laura

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Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition by Monaghan, Laura, Massett, Matthew Edward, Bunschoten, Roderick P, Pirvan, Petrisor Alin, Hoose, Alex, Park, Taeju, Bittencourt-Silvestre, Joana, Liskamp, Robert M J, Jørgensen, Heather G, Huang, Xu

“…Epigenetic therapies are emerging as a promising therapeutic strategy for acute myeloid leukemia (AML), exemplified by advances in the development of…”
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A molecular signature for delayed graft function by McGuinness, Dagmara, Mohammed, Suhaib, Monaghan, Laura, Wilson, Paul A., Kingsmore, David B., Shapter, Oliver, Stevenson, Karen S., Coley, Shana M., Devey, Luke, Kirkpatrick, Robert B., Shiels, Paul G.

“…Chronic kidney disease and associated comorbidities (diabetes, cardiovascular diseases) manifest with an accelerated ageing phenotype, leading ultimately to…”
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The Histone Demethylase KDM4A Is Required to Sustain H3K9me3/H3K27me3 Epigenetic States and Oncogenesis in MLL-AF9 Acute Myeloid Leukemia by Massett, Matthew E, Mannion, Niamh, Monaghan, Laura, Bittencourt-Silvestre, Joana, Marmiroli, Sandra, Liskamp, Robert M J, Michie, Alison M, Vetrie, David, Huang, Xu

“…Acute Myeloid Leukemia (AML) is an aggressive heterogeneous hematological malignancy. Persistence of leukemia stem cells (LSC) drive AML leukemogenesis,…”
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α-Functional glycopolymers: New materials for (poly)peptide conjugation by Ladmiral, Vincent, Monaghan, Laura, Mantovani, Giuseppe, Haddleton, David M.

“…The synthesis and characterization of a number of N-(hydroxy)succinimidyl ester-terminated glycopolymers obtained via copper(I)-catalysed living radical…”
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Rabbit-proof fence: Çit by Noyce, Phillip, Sampi, Everlyn, Sansbury, Tianna, Monaghan, Laura, Branagh, Kenneth

“…30'lı yıllarda yaşanmış gerçek bir olaydan yola çıkılarak gerçekleştirildi. 1931 yılında Avustralya yerlisi çocuklar ailelerinden koparılarak uzaklarda bir…”
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a-functional glycopolymers: new materials for (poly)peptide conjugation by Ladmiral, Vincent, Monaghan, Laura, Mantovani, Giuseppe, Haddleton, David M

“…The synthesis and characterization of a number of N-(hydroxy)succinimidyl ester-terminated glycopolymers obtained via copper(I)-catalysed living radical…”
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α-Functional glycopolymers : New materials for (poly)peptide conjugation : Controlled macromolecular synthesis and controlled architectures: Supramolecular polymer assemblies by LADMIRAL, Vincent, MONAGHAN, Laura, MANTOVANI, Giuseppe, HADDLETON, David M

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