Search Results - "Monaghan, D T"

NR2B- and NR2D-containing synaptic NMDA receptors in developing rat substantia nigra pars compacta dopaminergic neurones by Brothwell, S. L. C., Barber, J. L., Monaghan, D. T., Jane, D. E., Gibb, A. J., Jones, S.

“…NMDA receptors are present at glutamatergic synapses throughout the brain, and are important for the development and plasticity of neural circuits. Their…”
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Functional heterogeneity of NMDA receptors in rat substantia nigra pars compacta and reticulata neurones by Suárez, F., Zhao, Q., Monaghan, D. T., Jane, D. E., Jones, S., Gibb, A. J.

“…The nigra substantia nigra pars compacta (SNc) and substantia pars reticulata (SNr) form two major basal ganglia components with different functional roles…”
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Insulin Causes a Transient Tyrosine Phosphorylation of NR2A and NR2B NMDA Receptor Subunits in Rat Hippocampus by Christie, J. M., Wenthold, R. J., Monaghan, D. T.

“…: NMDA receptors play a critical role in various aspects of CNS function. Hence, it is important to identify mechanisms that regulate NMDA receptor activity…”
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GluN2D N-Methyl-d-Aspartate Receptor Subunit Contribution to the Stimulation of Brain Activity and Gamma Oscillations by Ketamine: Implications for Schizophrenia by Sapkota, Kiran, Mao, Zhihao, Synowicki, Paul, Lieber, Dillon, Liu, Meng, Ikezu, Tsuneya, Gautam, Vivek, Monaghan, Daniel T

“…The dissociative anesthetic ketamine elicits symptoms of schizophrenia at subanesthetic doses by blocking N-methyl-d-aspartate receptors (NMDARs). This…”
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Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain by Monaghan, DT, Cotman, CW

“…N-methyl-D-aspartate (NMDA) is an acidic amino acid which depolarizes neurons by selectively interacting with a distinct class of excitatory amino acid…”
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Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators by France, G., Volianskis, R., Ingram, R., Bannister, N., Rothärmel, R., Irvine, M.W., Fang, G., Burnell, E.S., Sapkota, K., Costa, B.M., Chopra, D.A., Dravid, S.M., Michael-Titus, A.T., Monaghan, D.T., Georgiou, J., Bortolotto, Z.A., Jane, D.E., Collingridge, G.L., Volianskis, A.

“…Different types of memory are thought to rely on different types of synaptic plasticity, many of which depend on the activation of the N-Methyl-D Aspartate…”
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Distinct NMDA Receptor Subpopulations Contribute to Long-Term Potentiation and Long- Term Depression Induction by Hrabetova, Sabina, Serrano, Peter, Blace, Nancy, Tse, Heong W, Skifter, Donald A, Jane, David E, Monaghan, Daniel T, Sacktor, Todd Charlton

“…Long-term potentiation (LTP) and long-term depression (LTD) are persistent modifications of synaptic strength that have been implicated in learning, memory,…”
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The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system by Monaghan, D T, Bridges, R J, Cotman, C W

“…Data on the properties of the receptor types is discussed, including: the increasingly complicated pharmacological profile of the NMDA receptor-ionophore…”
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The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition by Buller, AL, Larson, HC, Schneider, BE, Beaton, JA, Morrisett, RA, Monaghan, DT

“…The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and the recently identified NMDA…”
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Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity by Cotman, C W, Monaghan, D T, Ganong, A H

“…The study of excitatory amino acids as neurotransmitters has recently resulted in many new and fundamental concepts in neuroscience. Much of this progress…”
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Two Classes of N-methyl-D-aspartate Recognition Sites: Differential Distribution and Differential Regulation by Glycine by Monaghan, Daniel T., Olverman, Henry J., Nguyen, Long, Watkins, Jeffrey C., Cotman, Carl W.

“…The N-methyl-D-aspartate (NMDA) receptor, a subtype of excitatory amino acid receptor, mediates synaptic responses in many regions of the central nervous…”
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N‐methyl‐D‐aspartate receptor agonists modulate homocysteine‐induced developmental abnormalities by Rosenquist, T. H., Schneider, A. M., Monaghan, D. T.

“…ABSTRACTWe showed previously that the induction of neural crest (NC) and neural tube (NT) defects is a general property of N‐methyl‐D‐aspartate receptor…”
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Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor by Palmer, E, Monaghan, D T, Cotman, C W

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[3H]Homoquinolinate Binds to a Subpopulation of NMDA Receptors and to a Novel Binding Site by Brown, J. C., Tse, H. W., Skifter, D. A., Christie, J. M., Andaloro, V. J., Kemp, M. C., Watkins, J. C., Jane, D. E., Monaghan, D. T.

“…: NMDA receptors mediate several important functions in the CNS; however, little is known about the pharmacology, biochemistry, and function of distinct NMDA…”
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Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes by Buller, Amy L, Monaghan, Daniel T

“…The pharmacology of recombinant NR1a/NR2D NMDA receptors expressed in Xenopus oocytes was examined and compared to the pharmacology of NR1a/NR2A, NR1a/NR2B and…”
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Identification and Properties of N-methyl-D-aspartate Receptors in Rat Brain Synaptic Plasma Membranes by Monaghan, Daniel T., Cotman, Carl W.

“…The excitatory amino acid receptors selectively activated by N-methyl-D-aspartate (N-Me-D-Asp) (also known as NMDA) are a major determinant of central nervous…”
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ERK2 Activation by Homocysteine in Vascular Smooth Muscle Cells by Brown, J.C., Rosenquist, T.H., Monaghan, D.T.

“…Homocysteine at abnormally high levels is an independent risk factor for atherosclerosis and may be a key factor in atherogenesis. Since homocysteine (Hcys)…”
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Identification of a novel N-methyl-D-aspartate receptor population in the rat medial thalamus by Beaton, J A, Stemsrud, K, Monaghan, D T

“…To evaluate the possibility of pharmacologically distinct N-methyl-D-aspartate (NMDA) receptor subtypes, quantitative autoradiography was used to determine the…”
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Insulin potentiates N-methyl- d-aspartate receptor activity in Xenopus oocytes and rat hippocampus by Liu, Lifei, Brown, James C., Webster, Wallace W., Morrisett, Richard A., Monaghan, Daniel T.

“…Growth factor signal transduction pathways have recently been shown to affect voltage-gated ion channel activity. In this study we report that insulin can…”
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Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography by Monaghan, D T, Yao, D, Cotman, C W

“…Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) is a potent neuroexcitatory compound which acts at the quisqualate class of excitatory amino…”
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