Search Results - "Mommersteeg, Mathilda T. M."

Tbx18 and the fate of epicardial progenitors by Christoffels, Vincent M, Grieskamp, Thomas, Norden, Julia, Mommersteeg, Mathilda T. M, Rudat, Carsten, Kispert, Andreas

“…Arising from: C.-L. Cai et al. Nature 454, 104-108 (2008); Cai et al. replyUncovering the origins of myocardial cells is important for understanding and…”
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Transcription Factor Tbx3 Is Required for the Specification of the Atrioventricular Conduction System by Bakker, Martijn L, Boukens, Bastiaan J, Mommersteeg, Mathilda T.M, Brons, Janynke F, Wakker, Vincent, Moorman, Antoon F.M, Christoffels, Vincent M

“…The cardiac conduction system consists of distinctive heart muscle cells that initiate and propagate the electric impulse required for coordinated contraction…”
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The ambiguous role of NKX2-5 mutations in thyroid dysgenesis by van Engelen, Klaartje, Mommersteeg, Mathilda T M, Baars, Marieke J H, Lam, Jan, Ilgun, Aho, van Trotsenburg, A S Paul, Smets, Anne M J B, Christoffels, Vincent M, Mulder, Barbara J M, Postma, Alex V

“…NKX2-5 is a homeodomain-containing transcription factor implied in both heart and thyroid development. Numerous mutations in NKX2-5 have been reported in…”
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Pitx2c and Nkx2-5 Are Required for the Formation and Identity of the Pulmonary Myocardium by Mommersteeg, Mathilda T.M, Brown, Nigel A, Prall, Owen W.J, de Gier-de Vries, Corrie, Harvey, Richard P, Moorman, Antoon F.M, Christoffels, Vincent M

“…The pulmonary vein is sleeved by myocardium, which is a major source of atrial fibrillation and is involved in congenital sinus venosus defects. Little is…”
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Formation of the Sinus Node Head and Differentiation of Sinus Node Myocardium Are Independently Regulated by Tbx18 and Tbx3 by Wiese, Cornelia, Grieskamp, Thomas, Airik, Rannar, Mommersteeg, Mathilda T.M, Gardiwal, Ajmal, de Gier-de Vries, Corrie, Schuster-Gossler, Karin, Moorman, Antoon F.M, Kispert, Andreas, Christoffels, Vincent M

“…The sinus node (or sinoatrial node [SAN]), the pacemaker of the heart, is a functionally and structurally heterogeneous tissue, which consists of a large…”
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Embryonic Tbx3 + cardiomyocytes form the mature cardiac conduction system by progressive fate restriction by Mohan, Rajiv A, Mommersteeg, Mathilda T M, Domínguez, Jorge N, Choquet, Caroline, Wakker, Vincent, de Gier-de Vries, Corrie, Boink, Gerard J J, Boukens, Bastiaan J, Miquerol, Lucile, Verkerk, Arie O, Christoffels, Vincent M

“…A small network of spontaneously active Tbx3 cardiomyocytes forms the cardiac conduction system (CCS) in adults. Understanding the origin and mechanism of…”
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The sinus venosus progenitors separate and diversify from the first and second heart fields early in development by Mommersteeg, Mathilda T.M., Domínguez, Jorge N., Wiese, Cornelia, Norden, Julia, de Gier-de Vries, Corrie, Burch, John B.E., Kispert, Andreas, Brown, Nigel A., Moorman, Antoon F.M., Christoffels, Vincent M.

“…Aims During development, the heart tube grows by differentiation of Isl1+/Nkx2-5+ progenitors to the arterial and venous pole and dorsal mesocardium. However,…”
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Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development by Zhao, Juanjuan, Bruche, Susann, Potts, Helen G, Davies, Benjamin, Mommersteeg, Mathilda T M

“…Background Binding of Slit ligands to their Robo receptors regulates signaling pathways that are important for heart development. Genetic variants in and have…”
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Molecular Pathway for the Localized Formation of the Sinoatrial Node by Mommersteeg, Mathilda T.M, Hoogaars, Willem M.H, Prall, Owen W.J, de Gier-de Vries, Corrie, Wiese, Cornelia, Clout, Danielle E.W, Papaioannou, Virginia E, Brown, Nigel A, Harvey, Richard P, Moorman, Antoon F.M, Christoffels, Vincent M

“…The sinoatrial node, which resides at the junction of the right atrium and the superior caval vein, contains specialized myocardial cells that initiate the…”
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Robo1 modulates proliferation and neurogenesis in the developing neocortex by Yeh, Mason L, Gonda, Yuko, Mommersteeg, Mathilda T M, Barber, Melissa, Ypsilanti, Athena R, Hanashima, Carina, Parnavelas, John G, Andrews, William D

“…The elaborate cytoarchitecture of the mammalian neocortex requires the timely production of its constituent pyramidal neurons and interneurons and their…”
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Developmental Origin, Growth, and Three-Dimensional Architecture of the Atrioventricular Conduction Axis of the Mouse Heart by Aanhaanen, Wim T.J, Mommersteeg, Mathilda T.M, Norden, Julia, Wakker, Vincent, de Gier-de Vries, Corrie, Anderson, Robert H, Kispert, Andreas, Moorman, Antoon F.M, Christoffels, Vincent M

“…RATIONALE:The clinically important atrioventricular conduction axis is structurally complex and heterogeneous, and its molecular composition and developmental…”
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Formation of the Venous Pole of the Heart From an Nkx2–5–Negative Precursor Population Requires Tbx18 by Christoffels, Vincent M, Mommersteeg, Mathilda T.M, Trowe, Mark-Oliver, Prall, Owen W.J, de Gier-de Vries, Corrie, Soufan, Alexandre T, Bussen, Markus, Schuster-Gossler, Karin, Harvey, Richard P, Moorman, Antoon F.M, Kispert, Andreas

“…The venous pole of the mammalian heart is a structurally and electrically complex region, yet the lineage and molecular mechanisms underlying its formation…”
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Unlocking the Secrets of the Regenerating Fish Heart: Comparing Regenerative Models to Shed Light on Successful Regeneration by Potts, Helen G, Stockdale, William T, Mommersteeg, Mathilda T M

“…The adult human heart cannot repair itself after injury and, instead, forms a permanent fibrotic scar that impairs cardiac function and can lead to incurable…”
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Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method by Potts, Helen G, Lemieux, Madeleine E, Rice, Edward S, Warren, Wesley, Choudhury, Robin P, Mommersteeg, Mathilda T M

“…Advances in sequencing and assembly technology have led to the creation of genome assemblies for a wide variety of non-model organisms. The rapid production…”
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Slit–Robo signalling in heart development by Zhao, Juanjuan, Mommersteeg, Mathilda T M

“…Abstract The Slit ligands and their Robo receptors are well-known for their roles during axon guidance in the central nervous system but are still relatively…”
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Extraordinary model systems for regeneration by Accorsi, Alice, Guo, Longhua, Marshall, Wallace F, Mommersteeg, Mathilda T M, Nakajima, Yu-Ichiro

“…Regeneration is the remarkable phenomenon through which an organism can regrow lost or damaged parts with fully functional replacements, including complex…”
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Two Distinct Pools of Mesenchyme Contribute to the Development of the Atrial Septum by Mommersteeg, Mathilda T.M, Soufan, Alexandre T, de Lange, Frederik J, van den Hoff, Maurice J.B, Anderson, Robert H, Christoffels, Vincent M, Moorman, Antoon F.M

“…Closure of the primary atrial foramen is achieved by fusion of the atrioventricular cushions with the mesenchymal cap on the leading edge of the muscular…”
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Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration by Koth, Jana, Wang, Xiaonan, Killen, Abigail C, Stockdale, William T, Potts, Helen G, Jefferson, Andrew, Bonkhofer, Florian, Riley, Paul R, Patient, Roger K, Göttgens, Berthold, Mommersteeg, Mathilda T M

“…Runx1 is a transcription factor that plays a key role in determining the proliferative and differential state of multiple cell types, during both development…”
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A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution by Warren, Wesley C., Boggs, Tyler E., Borowsky, Richard, Carlson, Brian M., Ferrufino, Estephany, Gross, Joshua B., Hillier, LaDeana, Hu, Zhilian, Keene, Alex C., Kenzior, Alexander, Kowalko, Johanna E., Tomlinson, Chad, Kremitzki, Milinn, Lemieux, Madeleine E., Graves-Lindsay, Tina, McGaugh, Suzanne E., Miller, Jeffrey T., Mommersteeg, Mathilda T. M., Moran, Rachel L., Peuß, Robert, Rice, Edward S., Riddle, Misty R., Sifuentes-Romero, Itzel, Stanhope, Bethany A., Tabin, Clifford J., Thakur, Sunishka, Yamamoto, Yoshiyuki, Rohner, Nicolas

“…Identifying the genetic factors that underlie complex traits is central to understanding the mechanistic underpinnings of evolution. Cave-dwelling Astyanax…”
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Heart Regeneration in the Mexican Cavefish by Stockdale, William T., Lemieux, Madeleine E., Killen, Abigail C., Zhao, Juanjuan, Hu, Zhilian, Riepsaame, Joey, Hamilton, Noémie, Kudoh, Tetsuhiro, Riley, Paul R., van Aerle, Ronny, Yamamoto, Yoshiyuki, Mommersteeg, Mathilda T.M.

“…Although Astyanax mexicanus surface fish regenerate their hearts after injury, their Pachón cave-dwelling counterparts cannot and, instead, form a permanent…”
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