Search Results - "Momburg, Frank"

HLA-E Peptide Repertoire and Dimorphism-Centerpieces in the Adaptive NK Cell Puzzle? by Rölle, Alexander, Jäger, Dirk, Momburg, Frank

“…Adaptive Natural Killer (NK) cells, a heterogenous subpopulation of human NK cells with a unique phenotypic and functional signature, became arguably one of…”
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CD2–CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection by Rölle, Alexander, Halenius, Anne, Ewen, Eva‐Maria, Cerwenka, Adelheid, Hengel, Hartmut, Momburg, Frank

“…The existence and expansion of adaptive NK‐cell subsets have been linked to HCMV infection. Phenotypically, a majority of adaptive NK cells expresses the…”
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Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins by Debelec-Butuner, Bilge, Quitt, Oliver, Schreiber, Sophia, Momburg, Frank, Wisskirchen, Karin, Protzer, Ulrike

“…Despite the availability of an effective prophylactic vaccine, 820,000 people die annually of hepatitis B virus (HBV)-related liver disease according to WHO…”
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The ER Aminopeptidase, ERAP1, Trims Precursors to Lengths of MHC Class I Peptides by a "Molecular Ruler" Mechanism by Shih-Chung Chang, Momburg, Frank, Nidhi Bhutani, Goldberg, Alfred L.

“…Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an IFN-γ-induced aminopeptidase in the endoplasmic reticulum that trims longer precursors to the antigenic…”
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Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning by Gerke, Carolin, Bauersfeld, Liane, Schirmeister, Ivo, Mireisz, Chiara Noemi-Marie, Oberhardt, Valerie, Mery, Lea, Wu, Di, Jürges, Christopher Sebastian, Spaapen, Robbert M, Mussolino, Claudio, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Dölken, Lars, Paster, Wolfgang, Erhard, Florian, Hofmann, Maike, Schlosser, Andreas, Hengel, Hartmut, Momburg, Frank, Halenius, Anne

“…Human leucocyte antigen class I (HLA-I) molecules play a central role for both NK and T-cell responses that prevent serious human cytomegalovirus (HCMV)…”
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Activation of Natural Killer Cells by Newcastle Disease Virus Hemagglutinin-Neuraminidase by JARAHIAN, Mostafa, WATZL, Carsten, FOURNIER, Philippe, ARNOLD, Annette, DJANDJI, Dominik, ZAHEDI, Sarah, CERWENKA, Adelheid, PASCHEN, Annette, SCHIRRMACHER, Volker, MOMBURG, Frank

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Conserved, Lipid-Mediated Sorting Mechanism of Yeast Ist2 and Mammalian STIM Proteins to the Peripheral ER by Ercan, Ebru, Momburg, Frank, Engel, Ulrike, Temmerman, Koen, Nickel, Walter, Seedorf, Matthias

“…Sorting of yeast Ist2 to the plasma membrane (PM) or the cortical endoplasmic reticulum (ER) requires a cortical sorting signal (CSSIst²) that interacts with…”
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NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme by Murad, Shafiq, Michen, Susanne, Becker, Alexander, Füssel, Monika, Schackert, Gabriele, Tonn, Torsten, Momburg, Frank, Temme, Achim

“…In glioblastoma, non-classical human leucocyte antigen E (HLA-E) and HLA-G are frequently overexpressed. HLA-E loaded with peptides derived from HLA class I…”
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Co-Stimulatory Bispecific Antibodies Induce Enhanced T Cell Activation and Tumor Cell Killing in Breast Cancer Models by Warwas, Karsten M, Meyer, Marten, Gonçalves, Márcia, Moldenhauer, Gerhard, Bulbuc, Nadja, Knabe, Susanne, Luckner-Minden, Claudia, Ziegelmeier, Claudia, Heussel, Claus Peter, Zörnig, Inka, Jäger, Dirk, Momburg, Frank

“…Although T cell-recruiting CD3-binding bispecific antibodies (BiMAb) have been proven to be clinically effective for hematologic malignancies, the success of…”
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HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11 by Zimmermann, Cosima, Kowalewski, Daniel, Bauersfeld, Liane, Hildenbrand, Andreas, Gerke, Carolin, Schwarzmüller, Magdalena, Le-Trilling, Vu Thuy Khanh, Stevanovic, Stefan, Hengel, Hartmut, Momburg, Frank, Halenius, Anne

“…To escape CD8+ T-cell immunity, human cytomegalovirus (HCMV) US11 redirects MHC-I for rapid ER-associated proteolytic degradation (ERAD). In humans, classical…”
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Long-peptide vaccination with driver gene mutations in p53 and Kras induces cancer mutation-specific effector as well as regulatory T cell responses by Quandt, Jasmin, Schlude, Christoph, Bartoschek, Michael, Will, Rainer, Cid-Arregui, Angel, Schölch, Sebastian, Reissfelder, Christoph, Weitz, Jürgen, Schneider, Martin, Wiemann, Stefan, Momburg, Frank, Beckhove, Philipp

“…Mutated proteins arising from somatic mutations in tumors are promising targets for cancer immunotherapy. They represent true tumor-specific antigens (TSAs) as…”
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Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells by Soto, Karla E G, Loureiro, Liliana R, Bartsch, Tabea, Arndt, Claudia, Kegler, Alexandra, Mitwasi, Nicola, Drewitz, Laura, Hoffmann, Lydia, Saleh, Haidy A, Crespo, Eugenia, Mehnert, Maria, Daglar, Cansu, Abken, Hinrich, Momburg, Frank, Bachmann, Michael, Feldmann, Anja

“…Despite the success of chimeric antigen receptor (CAR) T-cells especially for treating hematological malignancies, critical drawbacks, such as "on-target,…”
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Modulation of NKp30- and NKp46-mediated natural killer cell responses by poxviral hemagglutinin by Jarahian, Mostafa, Fiedler, Manuela, Cohnen, André, Djandji, Dominik, Hämmerling, Günter J, Gati, Cornelius, Cerwenka, Adelheid, Turner, Peter C, Moyer, Richard W, Watzl, Carsten, Hengel, Hartmut, Momburg, Frank

“…Natural killer (NK) cells are an important element in the immune defense against the orthopox family members vaccinia virus (VV) and ectromelia virus (ECTV)…”
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MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection by Meyer, Marten, Parpoulas, Christina, Barthélémy, Titouan, Becker, Jonas P, Charoentong, Pornpimol, Lyu, Yanhong, Börsig, Selina, Bulbuc, Nadja, Tessmer, Claudia, Weinacht, Lisa, Ibberson, David, Schmidt, Patrick, Pipkorn, Rüdiger, Eichmüller, Stefan B, Steinberger, Peter, Lindner, Katharina, Poschke, Isabel, Platten, Michael, Fröhling, Stefan, Riemer, Angelika B, Hassel, Jessica C, Roberti, Maria Paula, Jäger, Dirk, Zörnig, Inka, Momburg, Frank

“…Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and…”
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A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle by Matschulla, Tony, Berry, Richard, Gerke, Carolin, Döring, Marius, Busch, Julia, Paijo, Jennifer, Kalinke, Ulrich, Momburg, Frank, Hengel, Hartmut, Halenius, Anne

“…The transporter associated with antigen processing (TAP) translocates antigenic peptides into the endoplasmic reticulum (ER) lumen for loading onto MHC class I…”
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Activating Natural Killer Cell Receptors, Selectins, and Inhibitory Siglecs Recognize Ebolavirus Glycoprotein by Jarahian, Mostafa, Marstaller, Katharina, Banna, Nadine, Ahani, Roshanak, Etemadzadeh, Mohammad Hossein, Boller, Lea K., Azadmanesh, Kayhan, Cid-Arregui, Angel, Khezri, Abdolrahman, Berger, Martin R., Momburg, Frank, Watzl, Carsten

“…Expression of the extensively glycosylated Ebolavirus glycoprotein (EBOV-GP) induces physical alterations of surface molecules and plays a crucial role in…”
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Multiple Residues in the Transmembrane Helix and Connecting Peptide of Mouse Tapasin Stabilize the Transporter Associated with the Antigen-processing TAP2 Subunit by Papadopoulos, Martina, Momburg, Frank

“…The type I endoplasmic reticulum (ER) glycoprotein tapasin (Tpn) is essential for loading of major histocompatibility complex class I (MHC-I) molecules with an…”
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Expression analysis of the ligands for the Natural Killer cell receptors NKp30 and NKp44 by Byrd, Andreina, Hoffmann, Sabrina C, Jarahian, Mostafa, Momburg, Frank, Watzl, Carsten

“…The natural cytotoxicity receptors (NCR) are important to stimulate the activity of Natural Killer (NK) cells against transformed cells. Identification of NCR…”
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The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1 by Evnouchidou, Irini, Momburg, Frank, Papakyriakou, Athanasios, Chroni, Angeliki, Leondiadis, Leondios, Chang, Shih-Chung, Goldberg, Alfred L, Stratikos, Efstratios

“…Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims N-terminally extended antigenic peptide precursors down to mature antigenic peptides for presentation by…”
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Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription by HALENIUS, Anne, HAUKA, Sebastian, DÖLKEN, Lars, STINDT, Jan, REINHARD, Henrike, WIEK, Constanze, HANENBERG, Helmut, KOSZINOWSKI, Ulrich H, MOMBURG, Frank, HENGEL, Hartmut

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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