Search Results - "Molugu, Sudheer K."

Structural insights on TRPV5 gating by endogenous modulators by Hughes, Taylor E. T., Pumroy, Ruth A., Yazici, Aysenur Torun, Kasimova, Marina A., Fluck, Edwin C., Huynh, Kevin W., Samanta, Amrita, Molugu, Sudheer K., Zhou, Z. Hong, Carnevale, Vincenzo, Rohacs, Tibor, Moiseenkova-Bell, Vera Y.

“…TRPV5 is a transient receptor potential channel involved in calcium reabsorption. Here we investigate the interaction of two endogenous modulators with TRPV5…”
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Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis by Calton, Christine M, Bronnimann, Matthew P, Manson, Ariana R, Li, Shuaizhi, Chapman, Janice A, Suarez-Berumen, Marcela, Williamson, Tatum R, Molugu, Sudheer K, Bernal, Ricardo A, Campos, Samuel K

“…The human papillomavirus type 16 (HPV16) L2 protein acts as a chaperone to ensure that the viral genome (vDNA) traffics from endosomes to the trans-Golgi…”
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The human mitochondrial Hsp60 in the APO conformation forms a stable tetradecameric complex by Enriquez, Adrian S, Rojo, Humberto M, Bhatt, Jay M, Molugu, Sudheer K, Hildenbrand, Zacariah L, Bernal, Ricardo A

“…The human mitochondrial chaperonin is a macromolecular machine that catalyzes the proper folding of mitochondrial proteins and is of vital importance to all…”
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Structural and Functional Insights into the Evolution and Stress Adaptation of Type II Chaperonins by Chaston, Jessica J., Smits, Callum, Aragão, David, Wong, Andrew S.W., Ahsan, Bilal, Sandin, Sara, Molugu, Sudheer K., Molugu, Sanjay K., Bernal, Ricardo A., Stock, Daniela, Stewart, Alastair G.

“…Chaperonins are essential biological complexes assisting protein folding in all kingdoms of life. Whereas homooligomeric bacterial GroEL binds hydrophobic…”
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Ring Separation Highlights the Protein-Folding Mechanism Used by the Phage EL-Encoded Chaperonin by Molugu, Sudheer K., Hildenbrand, Zacariah L., Morgan, David Gene, Sherman, Michael B., He, Lilin, Georgopoulos, Costa, Sernova, Natalia V., Kurochkina, Lidia P., Mesyanzhinov, Vadim V., Miroshnikov, Konstantin A., Bernal, Ricardo A.

“…Chaperonins are ubiquitous, ATP-dependent protein-folding molecular machines that are essential for all forms of life. Bacteriophage φEL encodes its own…”
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The C-H peripheral stalk base: a novel component in V1-ATPase assembly by Hildenbrand, Zacariah L, Molugu, Sudheer K, Stock, Daniela, Bernal, Ricardo A

“…Vacuolar ATPases (V-ATPases) are molecular machines responsible for creating electrochemical gradients and preserving pH-dependent cellular compartments by way…”
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Droplet Core Intermolecular Interactions and Block Copolymer Composition Heavily Influence Oil-In-Water Nanoemulsion Stability by Barres, Alexa R, Molugu, Sudheer K, Stewart, Phoebe L, Mecozzi, Sandro

“…Colloidal oil-in-water nanoemulsions are gaining increasing interest as a nanoparticle delivery system because of their large oil droplet core that can carry a…”
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High-yield expression and purification of the Hsp90-associated p23, FKBP52, HOP and SGTα proteins by Hildenbrand, Zacariah L., Molugu, Sudheer K., Paul, Atanu, Avila, Gustavo A., Herrera, Nadia, Xiao, Chuan, Cox, Marc B., Bernal, Ricardo A.

“…Hsp90 is a ubiquitous molecular chaperone that plays a key role in the malignant development of hormone-dependent pathologies such as cancer. An important role…”
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Debulking different Corona (SARS-CoV-2 delta, omicron, OC43) and Influenza (H1N1, H3N2) virus strains by plant viral trap proteins in chewing gums to decrease infection and transmission by Daniell, Henry, Nair, Smruti K., Guan, Hancheng, Guo, Yuwei, Kulchar, Rachel J., Torres, Marcelo D.T., Shahed-Al-Mahmud, Md, Wakade, Geetanjali, Liu, Yo-Min, Marques, Andrew D., Graham-Wooten, Jevon, Zhou, Wan, Wang, Ping, Molugu, Sudheer K., de Araujo, William R., de la Fuente-Nunez, Cesar, Ma, Che, Short, William R., Tebas, Pablo, Margulies, Kenneth B., Bushman, Frederic D., Mante, Francis K., Ricciardi, Robert P., Collman, Ronald G., Wolff, Mark S.

“…Because oral transmission of SARS-CoV-2 is 3–5 orders of magnitude higher than nasal transmission, we investigated debulking of oral viruses using viral trap…”
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Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle–Polymer Conjugates by Lee, Parker W, Isarov, Sergey A, Wallat, Jaqueline D, Molugu, Sudheer K, Shukla, Sourabh, Sun, Jessie E. P, Zhang, Jun, Zheng, Yi, Lucius Dougherty, Melissa, Konkolewicz, Dominik, Stewart, Phoebe L, Steinmetz, Nicole F, Hore, Michael J. A, Pokorski, Jonathan K

“…Covalent conjugation of water-soluble polymers to proteins is critical for evading immune surveillance in the field of biopharmaceuticals. The most common and…”
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Separation of E. coli chaperonin groEL from β-galactosidase without denaturation by Molugu, Sudheer K., Li, Jihui, Bernal, Ricardo A.

“…•Separation of β-galactosidase from groEL preparations.•β-Galactosidase in groEL preparations is tracked with the addition of ONPG.•GroEL purification to…”
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Single-Ring Intermediates Are Essential for Some Chaperonins by Bhatt, Jay M, Enriquez, Adrian S, Wang, Jinliang, Rojo, Humberto M, Molugu, Sudheer K, Hildenbrand, Zacariah L, Bernal, Ricardo A

“…Chaperonins are macromolecular complexes found throughout all kingdoms of life that assist unfolded proteins reach a biologically active state. Historically,…”
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Hsp90 can accommodate the simultaneous binding of the FKBP52 and HOP proteins by Hildenbrand, Zacariah L, Molugu, Sudheer K, Herrera, Nadia, Ramirez, Citlally, Xiao, Chuan, Bernal, Ricardo A

“…The regulation of steroidogenic hormone receptor-mediated activity plays an important role in the development of hormone-dependent cancers. For example, during…”
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Anchoring and scaffolding: V1-ATPase interactions with widespread implications by Hildenbrand, Zacariah L., Molugu, Sudheer K., Bernal, Ricardo A.

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Enzymatic characterization of a lysin encoded by bacteriophage EL by Tafoya, Diana A, Hildenbrand, Zacariah L, Herrera, Nadia, Molugu, Sudheer K, Mesyanzhinov, Vadim V, Miroshnikov, Konstantin A, Bernal, Ricardo A

“…The bacteriophage EL is a virus that specifically attacks the human pathogen . This phage carries a large genome that encodes for its own chaperonin which…”
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Photon Management through Virus‐Programmed Supramolecular Arrays by Veliz, Frank A., Ma, Yingfang, Molugu, Sudheer K., Tiu, Brylee David B., Stewart, Phoebe L., French, Roger H., Steinmetz, Nicole F.

“…Photon extraction and capture efficiency is a complex function of the material's composition, its molecular structure at the nanoscale, and the overall…”
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Anchoring and scaffolding: V 1 -ATPase interactions with widespread implications by Hildenbrand, Zacariah L., Molugu, Sudheer K., Bernal, Ricardo A.

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Ring Separation Highlights the Protein-Folding Mechanism Used by the Phage EL-Encoded Chaperonin by Molugu, Sudheer  K., Hildenbrand, Zacariah L., Morgan, David Gene, Sherman, Michael B., He, Lilin, Georgopoulos, Costa, Sernova, Natalia V., Kurochkina, Lidia P., Mesyanzhinov, Vadim V., Miroshnikov, Konstantin A., Bernal, Ricardo A.

“…Chaperonins are ubiquitous, ATP-dependent protein-folding molecular machines that are essential for all forms of life. Bacteriophage φEL encodes its own…”
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The C-H Peripheral Stalk Base: A Novel Component in V.sub.1-ATPase Assembly by Hildenbrand, Zacariah L, Molugu, Sudheer K, Stock, Daniela, Bernal, Ricardo A

“…Vacuolar ATPases (V-ATPases) are molecular machines responsible for creating electrochemical gradients and preserving pH-dependent cellular compartments by way…”
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Anchoring and scaffolding: V(1)-ATPase interactions with widespread implications by Hildenbrand, Zacariah L, Molugu, Sudheer K, Bernal, Ricardo A

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