Search Results - "Molotkovsky, J."

Elastic Membrane Deformations Govern Interleaflet Coupling of Lipid-Ordered Domains by Galimzyanov, Timur R, Molotkovsky, Rodion J, Bozdaganyan, Marine E, Cohen, Fredric S, Pohl, Peter, Akimov, Sergey A

“…The mechanism responsible for domain registration in two membrane leaflets has thus far remained enigmatic. Using continuum elasticity theory, we show that…”
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Continuum Models of Membrane Fusion: Evolution of the Theory by Akimov, Sergey A, Molotkovsky, Rodion J, Kuzmin, Peter I, Galimzyanov, Timur R, Batishchev, Oleg V

“…Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission, and sometimes morbid events of carcinogenesis and viral…”
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Heterogeneity in Lateral Distribution of Polycations at the Surface of Lipid Membrane: From the Experimental Data to the Theoretical Model by Molotkovsky, Rodion J., Galimzyanov, Timur R., Ermakov, Yury A.

“…Natural and synthetic polycations of different kinds attract substantial attention due to an increasing number of their applications in the biomedical industry…”
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A Model of Lipid Monolayer–Bilayer Fusion of Lipid Droplets and Peroxisomes by Kalutsky, Maksim A, Galimzyanov, Timur R, Molotkovsky, Rodion J

“…Lipid droplets are unique organelles that store neutral lipids encapsulated by the lipid monolayer. In some processes of cellular metabolism, lipid droplets…”
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Lateral Membrane Heterogeneity Regulates Viral-Induced Membrane Fusion during HIV Entry by Molotkovsky, Rodion J, Alexandrova, Veronika V, Galimzyanov, Timur R, Jiménez-Munguía, Irene, Pavlov, Konstantin V, Batishchev, Oleg V, Akimov, Sergey A

“…Sphingomyelin- and cholesterol- enriched membrane domains, commonly referred to as "rafts" play a crucial role in a large number of intra- and intercellular…”
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Switching between Successful and Dead-End Intermediates in Membrane Fusion by Molotkovsky, Rodion J, Galimzyanov, Timur R, Jiménez-Munguía, Irene, Pavlov, Konstantin V, Batishchev, Oleg V, Akimov, Sergey A

“…Fusion of cellular membranes during normal biological processes, including proliferation, or synaptic transmission, is mediated and controlled by sophisticated…”
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Membrane-Mediated Lateral Interactions Regulate the Lifetime of Gramicidin Channels by Kondrashov, Oleg V, Galimzyanov, Timur R, Molotkovsky, Rodion J, Batishchev, Oleg V, Akimov, Sergey A

“…The lipid matrix of cellular membranes is an elastic liquid crystalline medium. Its deformations regulate the functionality and interactions of membrane…”
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Heterodimeric V. nikolskii phospholipases A2 induce aggregation of the lipid bilayer by Alekseeva, A.S., Tretiakova, D.S., Chernikov, V.P., Utkin, Yu.N., Molotkovsky, J.G., Vodovozova, E.L., Boldyrev, I.A.

“…We report that the action of the heterodimeric phospholipases A2 (PLA2s) from Vipera nikolskii, which comprises enzymatically active basic subunit and inactive…”
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Energy Barrier of a Monolayer Stalk Formation during Lipid Droplet Fusion by Molotkovsky, R. J.

“…Lipid droplets are organelles responsible for the accumulation and breakdown of neutral fats in the human body. Lipid droplets have a monolayer shell of…”
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Behavior of Doxorubicin Lipophilic Conjugates in Liposomal Lipid Bilayers by Alekseeva, A. S., Chugunov, A. O., Volynsky, P. E., Onishchenko, N. R., Molotkovsky, J. G., Efremov, R. G., Boldyrev, I. A., Vodovozova, E. L.

“…Preparation of liposomal formulations containing water-soluble drugs in the form of lipophilic prodrugs in their lipid bilayer is of considerable interest…”
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Liposomes loaded with lipophilic prodrugs of methotrexate and melphalan as convenient drug delivery vehicles by Kuznetsova, N., Kandyba, A., Vostrov, I., Kadykov, V., Gaenko, G., Molotkovsky, J., Vodovozova, E.

“…Liposomal formulations prepared by extrusion from natural phospholipids and 1,2-dioleoylglycerol conjugates of methotrexate and melphalan (egg…”
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An expedient synthesis of fluorescent labeled ceramide-1-phosphate analogues by Boldyrev, I. A., Brown, R. E., Molotkovsky, J. G.

“…A synthesis for fluorescent analogs of ceramide-1-phosphate bearing 9-anthrylvinyl or 4,4-difluoro-3a,4a-diaza- s -indacene-8-yl (Me 4 -BODIPY) fluorophore at…”
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Fusion of Peroxisome and Lipid Droplet Membranes: Expansion of a π-Shaped Structure by Molotkovsky, R. J., Kuzmin, P. I.

“…Classical theory of fusion considers the fusion of bilayer membranes as a unification of the material of the membranes themselves and the water volumes…”
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New 4,4-difluoro-3a,4a-diaza-s-indacene (BODIPY)-labeled sphingolipids for membrane studies by Boldyrev, I. A, Molotkovsky, J. G

“…The synthesis of a series of new fluorescently labeled sphingolipids containing a 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl…”
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Inhomogeneity of polylysine adsorption layers on lipid membranes revealed by theoretical analysis of electrokinetic data and molecular dynamics simulations by Molotkovsky, Rodion J., Galimzyanov, Timur R., Khomich, Daria A., Nesterenko, Alexey M., Ermakov, Yury A.

“…[Display omitted] •Polylysine binding to anionic membrane leads to a very heterogeneous adsorption layer.•The adsorption layer's heterogeneity is registered in…”
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Antitumour activity of cytotoxic liposomes equipped with selectin ligand SiaLe(X), in a mouse mammary adenocarcinoma model by Vodovozova, E L, Moiseeva, E V, Grechko, G K, Gayenko, G P, Nifant'ev, N E, Bovin, N V, Molotkovsky, J G

“…The overexpression of lectins by malignant cells compared with normal ones can be used for the targeting of drug-loaded liposomes to tumours with the help of…”
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Galimzyanov et al. Reply by Galimzyanov, Timur R, Molotkovsky, Rodion J, Cohen, Fredric S, Pohl, Peter, Akimov, Sergey A

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The Effect of Transmembrane Protein Shape on Surrounding Lipid Domain Formation by Wetting by Molotkovsky, Rodion J, Galimzyanov, Timur R, Batishchev, Oleg V, Akimov, Sergey A

“…Signal transduction through cellular membranes requires the highly specific and coordinated work of specialized proteins. Proper functioning of these proteins…”
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Polypeptides on the Surface of Lipid Membranes. Theoretical Analysis of Electrokinetic Data by Molotkovsky, R. J., Galimzyanov, T. R., Ermakov, Yu. A.

“…A theoretical model describing experimental data on the electrophoretic mobility of liposomes, which are formed from mixtures of charged (cardiolipin) and…”
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Scanning electron microscopy study of neutrophil membrane tubulovesicular extensions (cytonemes) and their role in anchoring, aggregation and phagocytosis. The effect of nitric oxide by Galkina, Svetlana I., Molotkovsky, Julian G., Ullrich, Volker, Sud'ina, Galina F.

“…We have shown that human neutrophils develop dynamic thin and very long tubulovesicular extensions (cytonemes) upon adhesion to fibronectin, if cell spreading…”
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