Search Results - "Molokie, Robert"

COVID‐19 infection in patients with sickle cell disease by Hussain, Faiz A., Njoku, Franklin U., Saraf, Santosh L., Molokie, Robert E., Gordeuk, Victor R., Han, Jin

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Improved health care utilization and costs in transplanted versus non-transplanted adults with sickle cell disease by Saraf, Santosh L, Ghimire, Krishna, Patel, Pritesh, Sweiss, Karen, Gowhari, Michel, Molokie, Robert E, Gordeuk, Victor R, Rondelli, Damiano

“…Patients with sickle cell disease (SCD) have access to fewer health care resources and therapies compared to other diseases, which contributes to increased…”
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Differential Detection of Tumor Cells Using a Combination of Cell Rolling, Multivalent Binding, and Multiple Antibodies by Myung, Ja Hye, Gajjar, Khyati A, Chen, Jihua, Molokie, Robert E, Hong, Seungpyo

“…Effective quantification and in situ identification of circulating tumor cells (CTCs) in blood are still elusive because of the extreme rarity and…”
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S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort by Jhun, Ellie H, Sadhu, Nilanjana, He, Ying, Yao, Yingwei, Wilkie, Diana J, Molokie, Robert E, Wang, Zaijie Jim

“…Pain in sickle cell disease (SCD) is severe and multifaceted resulting in significant differences in its frequency and intensity among individuals. In this…”
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Voxelotor and albuminuria in adults with sickle cell anaemia by Han, Jin, Molokie, Robert E., Hussain, Faiz, Njoku, Franklin, Gordeuk, Victor R., Saraf, Santosh L.

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A new target for fetal hemoglobin reactivation by Rivers, Angela, Molokie, Robert, Lavelle, Donald

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GLP‐1 agonists and SGLT‐2 inhibitors in adults with sickle cell disease by Sun, Ryan, Srivastava, Anand, Derebail, Vimal K., Han, Jin, Molokie, Robert E., Gordeuk, Victor, Saraf, Santosh L.

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Reticulocyte mitochondrial retention increases reactive oxygen species and oxygen consumption in mouse models of sickle cell disease and phlebotomy-induced anemia by Gallivan, Anne, Alejandro, Mikail, Kanu, Amarachi, Zekaryas, Nebeyat, Horneman, Hart, Hong, Lenny K., Vinchinsky, Elliott, Lavelle, Don, Diamond, Alan M., Molokie, Robert E., Ramasamy, Jagadeesh, Rivers, Angela

“…•Reticulocytes and erythrocytes containing mitochondria in sickle cell disease mice exhibit elevated levels of reactive oxygen species (ROS) and increased…”
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COVID‐19 vaccination status and disease burden in patients with sickle cell disease by Han, Jin, Zhang, Xu, Molokie, Robert E., Njoku, Franklin U., Hussain, Faiz A., Farooqui, Marwah, Rizvi, Insia, Saraf, Santosh L., Gordeuk, Victor R.

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An alcohol dehydrogenase 7 gene polymorphism associates with both acute and chronic pain in sickle cell disease by Kashyap, Yavnika, He, Ying, Sadhu, Nilanjana, Yao, Yingwei, Wilkie, Diana J, Molokie, Robert E, Wang, Zaijie Jim

“…As the most distressing complication of sickle cell disease (SCD), pain is marked by considerable heterogenicity. In this study we explored the potential…”
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Vasopressin SNP pain factors and stress in sickle cell disease by Powell-Roach, Keesha L, Yao, Yingwei, Jhun, Ellie H, He, Ying, Suarez, Marie L, Ezenwa, Miriam O, Molokie, Robert E, Wang, Zaijie Jim, Wilkie, Diana J

“…Frequencies of single nucleotide polymorphisms (SNPs) from pain related candidate genes are available for individuals with sickle cell disease (SCD). One of…”
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Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study by Molokie, Robert, Lavelle, Donald, Gowhari, Michel, Pacini, Michael, Krauz, Lani, Hassan, Johara, Ibanez, Vinzon, Ruiz, Maria A, Ng, Kwok Peng, Woost, Philip, Radivoyevitch, Tomas, Pacelli, Daisy, Fada, Sherry, Rump, Matthew, Hsieh, Matthew, Tisdale, John F, Jacobberger, James, Phelps, Mitch, Engel, James Douglas, Saraf, Santhosh, Hsu, Lewis L, Gordeuk, Victor, DeSimone, Joseph, Saunthararajah, Yogen

“…Sickle cell disease (SCD), a congenital hemolytic anemia that exacts terrible global morbidity and mortality, is driven by polymerization of mutated sickle…”
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Dendrimer-Based Platform for Effective Capture of Tumor Cells after TGFβ1‑Induced Epithelial–Mesenchymal Transition by Myung, Ja Hye, Cha, Ashley, Tam, Kevin A, Poellmann, Michael, Borgeat, Alain, Sharifi, Roohollah, Molokie, Robert E, Votta-Velis, Gina, Hong, Seungpyo

“…Detection of circulating tumor cells (CTCs) relying on their expression of epithelial cell markers, such as epithelial cell adhesion molecule (EpCAM), has been…”
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HUMAN STUDY COMT and DRD3 haplotype-associated pain intensity and acute care utilization in adult sickle cell disease by Powell-Roach, Keesha L, Yao, Yingwei, Wallace, Margaret R, Chamala, Srikar, Cruz-Almeida, Yenisel, Jhun, Ellie, Molokie, Robert E, Wang, Zajie Jim, Wilkie, Diana J

“…A previous exploratory analysis of a COMT gene single-nucleotide polymorphism (SNP) and a DRD3 SNP by our group suggested possible contributions to…”
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Candidate gene association study suggests potential role of dopamine beta-hydroxylase in pain heterogeneity in sickle cell disease by Sadhu, Nilanjana, He, Ying, Yao, Yingwei, Wilkie, Diana J, Molokie, Robert E, Wang, Zaijie Jim

“…Pain is a lifelong companion of individuals with sickle cell disease (SCD) and has a severe impact on their quality of life. Both acute crisis pain and chronic…”
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Antimicrobial resistance is a risk factor for mortality in adults with sickle cell disease by Srisuwananukorn, Andrew, Han, Jin, Raslan, Rasha, Gowhari, Michel, Hussain, Faiz, Njoku, Franklin, Molokie, Robert E, Gordeuk, Victor R, Saraf, Santosh L

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Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease by Jagadeeswaran, Ramasamy, Vazquez, Benjamin A, Thiruppathi, Muthusamy, Ganesh, Balaji B, Ibanez, Vinzon, Cui, Shuaiying, Engel, James D, Diamond, Alan M, Molokie, Robert E, DeSimone, Joseph, Lavelle, Donald, Rivers, Angela

“…Sickle cell disease (SCD), an inherited blood disorder caused by a point mutation that renders hemoglobin susceptible to polymerization when deoxygenated,…”
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Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia by Saraf, Santosh L., Zhang, Xu, Kanias, Tamir, Lash, James P., Molokie, Robert E., Oza, Bharvi, Lai, Catherine, Rowe, Julie H., Gowhari, Michel, Hassan, Johara, DeSimone, Joseph, Machado, Roberto F., Gladwin, Mark T., Little, Jane A., Gordeuk, Victor R.

“…Summary To evaluate the association between haemoglobinuria and chronic kidney disease (CKD) in sickle cell anaemia (SCA), we analysed 356 adult haemoglobin SS…”
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APOL1, α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia by Saraf, Santosh L, Shah, Binal N, Zhang, Xu, Han, Jin, Tayo, Bamidele O, Abbasi, Taimur, Ostrower, Adam, Guzman, Elizabeth, Molokie, Robert E, Gowhari, Michel, Hassan, Johara, Jain, Shivi, Cooper, Richard S, Machado, Roberto F, Lash, James P, Gordeuk, Victor R

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CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice by He, Ying, Chen, Yan, Tian, Xuebi, Yang, Cheng, Lu, Jian, Xiao, Chun, DeSimone, Joseph, Wilkie, Diana J., Molokie, Robert E., Wang, Zaijie Jim

“…Pain is one of the most challenging and stressful conditions to patients with sickle cell disease (SCD) and their clinicians. Patients with SCD start…”
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