Search Results - "Molloy, Emer L"

Anatomy and bronchoscopy of the porcine lung. A model for translational respiratory medicine by Judge, Eoin P, Hughes, J M Lynne, Egan, Jim J, Maguire, Michael, Molloy, Emer L, O'Dea, Shirley

“…The porcine model has contributed significantly to biomedical research over many decades. The similar size and anatomy of pig and human organs make this model…”
Get full text

Vector-free intracellular delivery by reversible permeabilization by O'Dea, Shirley, Annibaldi, Valeria, Gallagher, Louise, Mulholland, Joanne, Molloy, Emer L, Breen, Conor J, Gilbert, Jennifer L, Martin, Darren S, Maguire, Michael, Curry, Fitz-Roy

“…Despite advances in intracellular delivery technologies, efficient methods are still required that are vector-free, can address a wide range of cargo types and…”
Get full text

Bone morphogenetic proteins enhance an epithelial-mesenchymal transition in normal airway epithelial cells during restitution of a disrupted epithelium by McCormack, Natasha, Molloy, Emer L, O'Dea, Shirley

“…Mechanisms of airway repair are poorly understood. It has been proposed that, following injury, progenitor populations such as club cells (Clara) become…”
Get full text

Delivery of nucleic acids to ex vivo porcine airways using electrospray by Riddell, Peter, Gilbert, Jennifer L., Molloy, Emer L., Finnegan, Shane, Egan, Jim J., O'Dea, Shirley

“…Aim of the Study: Nucleic acid-based therapies have the potential to provide clinically meaningful benefit across a wide spectrum of lung disease. However, in…”
Get full text

Bone morphogenetic protein signalling in airway epithelial cells during regeneration by Masterson, Joanne C., Molloy, Emer L., Gilbert, Jennifer L., McCormack, Natasha, Adams, Aine, O'Dea, Shirley

“…Mechanisms of lung regeneration after injury remain poorly understood. Bone morphogenetic protein 4 (BMP4) is critical for lung morphogenesis and regulates…”
Get full text

SMAD Signaling in the Airways of Healthy Rhesus Macaques versus Rhesus Macaques with Asthma Highlights a Relationship Between Inflammation and Bone Morphogenetic Proteins by Lynn, Therese M, Molloy, Emer L, Masterson, Joanne C, Glynn, Senan F, Costello, Richard W, Avdalovic, Mark V, Schelegle, Edward S, Miller, Lisa A, Hyde, Dallas M, O'Dea, Shirley

“…Bone morphogenetic protein (BMP) signaling is important for correct lung morphogenesis, and there is evidence of BMP signaling reactivation in lung diseases…”
Get full text

BMP4 induces an epithelial-mesenchymal transition-like response in adult airway epithelial cells by Molloy, Emer L., Adams, Aine, Moore, J. Bernadette, Masterson, JOANNE C., Madrigal-Estebas, Laura, Mahon, Bernard P., O'Dea, Shirley

“…Bone morphogenetic proteins (BMPs) are critical morphogens and play key roles in epithelial-mesenchymal transitions (EMTs) during embryogenesis. BMP4 is…”
Get full text

BMP2 and BMP4 differentially modulate extracellular matrix‐related gene expression in human lung epithelial cells by Moore, J. Bernadette, Adams, Aine, Molloy, Emer L., O'Dea, Shirley

“…Bone morphogenetic protein 4 (BMP4) is essential for normal lung morphogenesis although the underlying mechanisms are unknown. We are investigating whether…”
Get full text