Search Results - "Molloy, Eamonn S"

PML and rheumatology: the contribution of disease and drugs by Molloy, Eamonn S

“…Progressive multifocal leukoencephalopathy (PML), a rare, typically fatal, opportunistic infection caused by the JC virus, is becoming relevant to physicians…”
Get full text

Progressive multifocal leukoencephalopathy associated with immunosuppressive therapy in rheumatic diseases: Evolving role of biologic therapies by Molloy, Eamonn S., Calabrese, Leonard H.

“…Objective To evaluate the association of progressive multifocal leukoencephalopathy (PML) with immunosuppressive therapy for autoimmune rheumatic diseases…”
Get full text

Updated pharmacological management of rheumatoid arthritis for women before, during, and after pregnancy, reflecting recent guidelines by Murray, Kieran E., Moore, Louise, O’Brien, Celine, Clohessy, Anne, Brophy, Caroline, Minnock, Patricia, FitzGerald, Oliver, Molloy, Eamonn S., Mongey, Anne-Barbara, Higgins, Shane, Higgins, Mary F., Mc Auliffe, Fionnuala M., Veale, Douglas J.

“…Background Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease which can cause significant disability, morbidity, mortality, and…”
Get full text

Ustekinumab in Giant Cell Arteritis: Comment on the Article by Matza et al by Conway, Richard, Molloy, Eamonn S.

Get full text

Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer by Doherty, Glen A, Byrne, Sinead M, Molloy, Eamonn S, Malhotra, Vikrum, Austin, Sandra C, Kay, Elaine W, Murray, Frank E, Fitzgerald, Desmond J

“…Prostaglandin E2 (PGE2) is the major product of Cyclooxygenase-2 (COX-2) in colorectal cancer (CRC). We aimed to assess PGE2 cell surface receptors (EP 1-4) to…”
Get full text

The role of toll like receptors in giant cell arteritis by O'Neill, Lorraine, Molloy, Eamonn S

“…GCA is a common primary systemic vasculitis that results in granulomatous inflammation of medium to large arteries. Both innate and adaptive immune mechanisms…”
Get full text

Ustekinumab for refractory giant cell arteritis: A prospective 52-week trial by Conway, Richard, O'Neill, Lorraine, Gallagher, Phil, McCarthy, Geraldine M., Murphy, Conor C., Veale, Douglas J., Fearon, Ursula, Molloy, Eamonn S.

“…Giant cell arteritis (GCA) is the most common form of systemic vasculitis. Glucocorticoids are an effective treatment but have significant adverse events and…”
Get full text

Successful reconstruction of an ocular defect resulting from granulomatosis with polyangiitis, following treatment with rituximab by Kenny, Grace M, Holl-Ulrich, Konstanze, Fulcher, Timothy, McElnea, Elizabeth, Kavanagh, Eoin, Moriarty, Heather, Mulligan, Niall, Molloy, Eamonn S, McCarthy, Geraldine M

“…To report a unique case of orbital inflammatory disease which was ultimately diagnosed as granulomatosis with polyangitis (GPA) and thus successfully treated…”
Get full text

Ustekinumab for the treatment of refractory giant cell arteritis by Conway, Richard, O'Neill, Lorraine, O'Flynn, Eileen, Gallagher, Phil, McCarthy, Geraldine M, Murphy, Conor C, Veale, Douglas J, Fearon, Ursula, Molloy, Eamonn S

Get more information

Response to: ustekinumab inhibits Th1 and Th17 polarisation in a giant-cell arteritis patient by Samson et al by Conway, Richard, Fearon, Ursula, Molloy, Eamonn S

Get more information

Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis by Conway, Richard, O'Neill, Lorraine, McCarthy, Geraldine M, Murphy, Conor C, Fabre, Aurelie, Kennedy, Susan, Veale, Douglas J, Wade, Sarah M, Fearon, Ursula, Molloy, Eamonn S

“…The pathogenesis of giant cell arteritis (GCA) remains unclear. T 1 and T 17 pathways are implicated, but the proximal initiators and effector cytokines are…”
Get more information

The Risk of Progressive Multifocal Leukoencephalopathy in the Biologic Era: Prevention and Management by Molloy, Eamonn S, Calabrese, Cassandra M, Calabrese, Leonard H

“…Progressive multifocal leukoencephalopathy (PML) is a rare, typically fatal, demyelinating central nervous system infection caused by reactivation of the John…”
Get full text

IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation by Smith, Siobhan, Wu, Pei Wen, Seo, Jane J, Fernando, Thilini, Jin, Mengyao, Contreras, Jorge, Montano, Erica N, Gabhann, Joan Ní, Cunningham, Kyle, Widaa, Amro, McCarthy, Eoghan M, Molloy, Eamonn S, Kearns, Grainne, Murphy, Conor C, Kong, Weiping, Björkbacka, Harry, Kornfeld, Hardy, Forbess, Lindsy, Venuturupalli, Swamy, Ishimori, Mariko, Wallace, Daniel, Weisman, Michael H, Jefferies, Caroline A

“…Severe lung inflammation and alveolar hemorrhage can be life-threatening in systemic lupus erythematosus (SLE) patients if not treated early and aggressively…”
Get full text

Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: Are patients with systemic lupus erythematosus at particular risk? by Molloy, Eamonn S, Calabrese, Leonard H

“…Abstract Progressive multifocal leukoencephalopathy (PML) is a rare, frequently fatal, infectious complication occurring in immunocompromised patients. PML has…”
Get full text

Peroneal neuropathy in giant cell arteritis by Conway, Richard, Kinsella, Justin A, Molloy, Eamonn S

Get full text

Progressive multifocal leukoencephalopathy: A national estimate of frequency in systemic lupus erythematosus and other rheumatic diseases by Molloy, Eamonn S., Calabrese, Leonard H.

“…Objective Progressive multifocal leukoencephalopathy (PML) is a rare, typically fatal, central nervous system demyelinating disease that results from…”
Get full text

Basic calcium phosphate crystals: pathways to joint degeneration by Molloy, Eamonn S, McCarthy, Geraldine M

“…PURPOSE OF REVIEWBasic calcium phosphate crystals have long been associated with rheumatic syndromes. Although an understanding of the molecular mechanisms…”
Get full text

Diagnostic Utility of Computed Tomographic Angiography in Giant-Cell Arteritis by Conway, Richard, Smyth, Anna E, Kavanagh, Richard G, O’Donohoe, Rory L, Purcell, Yvonne, Heffernan, Eric J, Molloy, Eamonn S, McNeill, Graeme, Killeen, Ronan P

“…BACKGROUND AND PURPOSE—The diagnosis of giant-cell arteritis (GCA) is challenging. Superficial temporal artery biopsy and ultrasound are positive in only 50%…”
Get full text

Performance characteristics and predictors of temporal artery ultrasound for the diagnosis of giant cell arteritis in routine clinical practice in a prospective cohort by Conway, Richard, O'Neill, Lorraine, McCarthy, Geraldine M, Murphy, Conor C, Veale, Douglas J, Fearon, Ursula, Killeen, Ronan P, Heffernan, Eric J, Molloy, Eamonn S

“…The diagnosis of giant cell arteritis (GCA) is primarily a clinical one. Temporal artery (TA) ultrasound (US) has been proposed as a new diagnostic tool. We…”
Get full text

Targeted but not trouble-free: efalizumab and PML by Molloy, Eamonn S., Calabrese, Leonard H.

“…In April 2009, efalizumab was withdrawn from the market for the treatment of psoriasis after reports emerged of an association between long-term therapy and…”
Get full text