Search Results - "Mollgard, Lars"
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Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry
Published in Blood (2009)“…Acute myeloid leukemia (AML) is most common in the elderly, and most elderly are thought to be unfit for intensive treatment because of the risk of fatal…”
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Improved survival of men 50 to 75 years old with acute myeloid leukemia over a 20-year period
Published in Blood (31-10-2019)Get full text
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Clinical and genomic characterization of patients diagnosed with the provisional entity acute myeloid leukemia with BCR‐ABL1, a Swedish population‐based study
Published in Genes chromosomes & cancer (01-06-2021)“…Acute myeloid leukemia (AML) with t(9;22)(q34;q11), also known as AML with BCR‐ABL1, is a rare, provisional entity in the WHO 2016 classification and is…”
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Acute myeloid leukemia in very old patients
Published in Haematologica (Roma) (01-12-2018)Get full text
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NOX2‐dependent immunosuppression in chronic myelomonocytic leukemia
Published in Journal of leukocyte biology (01-08-2017)“…Human primary CMML cells produce immunosuppressive ROS that may impact on NK cell‐ and T cell‐mediated clearance of leukemic cells. Chronic myelomonocytic…”
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The prognostic impact of FLT3-ITD and NPM1 mutation in adult AML is age-dependent in the population-based setting
Published in Blood advances (24-03-2020)“…In acute myeloid leukemia (AML) FLT3 internal tandem duplication (ITD) and nucleophosmin 1 (NPM1) mutations provide prognostic information with clinical…”
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Hematopoietic Stem Cell Transplantation Rates and Long-Term Survival in Acute Myeloid and Lymphoblastic Leukemia: Real-World Population-Based Data From the Swedish Acute Leukemia Registry 1997-2006
Published in Cancer (2011)“…Allogeneic stem cell transplantation (alloSCT) reduces relapse rates in acute leukemia, but outcome is hampered by toxicity. Population-based data avoid…”
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Reduced Intensity transplantation vs chemotherapy in CR1. A prospective, pseudorandomized study in 50-70 year old AML patients
Published in Bone marrow transplantation (Basingstoke) (02-09-2024)“…The aim of this prospective, international multicenter, pseudorandomized study comparing RICT HCT to standard-of-care chemotherapy in intermediate- or…”
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Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population‐based study from the Swedish AML registry
Published in European journal of haematology (01-05-2017)“…Objectives and Methods To ascertain the incidence/clinical implications of isolated autosomal trisomies in adult acute myeloid leukemia (AML), all such cases…”
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Is there an impact of measurable residual disease as assessed by multiparameter flow cytometry on survival of AML patients treated in clinical practice? A population-based study
Published in Leukemia & lymphoma (2021)“…The Swedish national guidelines for treatment of acute myeloid leukemia (AML) recommend analysis of measurable residual disease (MRD) by multiparameter flow…”
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Prognostic significance of high hyperdiploid and triploid/tetraploid adult acute myeloid leukemia
Published in American journal of hematology (01-09-2015)“…To ascertain the clinical implications of high hyperdiploid (HH; 49–65 chromosomes) and triploid/tetraploid (TT; >65 chromosomes) adult acute myeloid leukemia…”
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Prevalence and Characteristics of Survivors from Adult Acute Myeloid Leukemia (AML) in Sweden 2014
Published in BLOOD (03-12-2015)“…The prevalence of survivors of adult AML has previously been calculated, but the prevalent population has not been characterized. We analysed all 6289 patients…”
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Poor Outcome in Secondary Acute Myeloid Leukemia (AML): A First Report From the Population-Based Swedish Acute Leukemia Registry
Published in Blood (16-11-2012)“…Abstract 130▪▪This icon denotes a clinically relevant abstract Secondary AML comprises AML patients with an antecedent hematological disorder (AHD) or previous…”
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Improved Survival of Patients with Acute Myeloid Leukemia Following Implementation of Swedish National Guidelines: Results from the AML Registry 1997-2013
Published in BLOOD (06-12-2014)“…Despite improved diagnostics and better understanding of AML biology, the basic chemotherapy has remained unchanged for decades, with no progress in outcome…”
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Secondary Acute Myeloid Leukemia and the Role of Allogeneic Stem Cell Transplantation in a Population-Based Setting
Published in Biology of blood and marrow transplantation (01-09-2019)“…•In a population-based setting, the proportion of patients with acute myeloid leukemia (AML) achieving complete remission who undergo allogeneic hematopoietic…”
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Early and Transient Microchimerism Associated with Complete Remission after Adoptively Transferred Haploidentical NK Cells Against High Risk Myelodysplastic Syndrome and Refractory Acute Myeloid Leukemia
Published in BLOOD (06-12-2014)“…Introduction: We here report from an ongoing phase I/II study of HLA-haploidentical NK cell therapy to patients with high-risk myelodysplastic syndrome (MDS)…”
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Journal Article Conference Proceeding -
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Allogeneic Transplantation in First Remission Improves Outcome in Secondary Acute Myeloid Leukemia
Published in BLOOD (2014)“…Allogeneic stem cell transplantation (SCT) is widely used as post-remission treatment in younger patients with poor or intermediate risk AML. Transplant…”
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Journal Article Conference Proceeding -
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Characterization and prognostic features of secondary acute myeloid leukemia in a population‐based setting: A report from the Swedish Acute Leukemia Registry
Published in American journal of hematology (2015)“…Patients with secondary acute myeloid leukemia (AML) often escape inclusion in clinical trials and thus, population‐based studies are crucial for its accurate…”
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