Search Results - "Mollenhauer, Brit"

Levodopa Equivalent Dose Conversion Factors: An Updated Proposal Including Opicapone and Safinamide by Schade, Sebastian, Mollenhauer, Brit, Trenkwalder, Claudia

Get full text

Prodromal Parkinson disease — time is brain by Weber, Sandrina, Mollenhauer, Brit

“…Biomarkers that predict conversion from isolated REM sleep behaviour disorder to Parkinson disease are urgently needed. A new study finds that detection of…”
Get full text

Prediagnostic presentation of Parkinson's disease in primary care: A case-control study by Mollenhauer, Brit

Get full text

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder by Heintz‐Buschart, Anna, Pandey, Urvashi, Wicke, Tamara, Sixel‐Döring, Friederike, Janzen, Annette, Sittig‐Wiegand, Elisabeth, Trenkwalder, Claudia, Oertel, Wolfgang H., Mollenhauer, Brit, Wilmes, Paul

“…ABSTRACT Background Increasing evidence connects the gut microbiota and the onset and/or phenotype of Parkinson's disease (PD). Differences in the abundances…”
Get full text

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity by Cantuti-Castelvetri, Ludovico, Ojha, Ravi, Pedro, Liliana D, Djannatian, Minou, Franz, Jonas, Kuivanen, Suvi, van der Meer, Franziska, Kallio, Katri, Kaya, Tuğberk, Anastasina, Maria, Smura, Teemu, Levanov, Lev, Szirovicza, Leonora, Tobi, Allan, Kallio-Kokko, Hannimari, Österlund, Pamela, Joensuu, Merja, Meunier, Frédéric A, Butcher, Sarah J, Winkler, Martin Sebastian, Mollenhauer, Brit, Helenius, Ari, Gokce, Ozgun, Teesalu, Tambet, Hepojoki, Jussi, Vapalahti, Olli, Stadelmann, Christine, Balistreri, Giuseppe, Simons, Mikael

“…The causative agent of coronavirus disease 2019 (COVID-19) is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For many viruses, tissue…”
Get full text

Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa) by Mollenhauer, Brit, Zimmermann, Johannes, Sixel‐Döring, Friederike, Focke, Niels K., Wicke, Tamara, Ebentheuer, Jens, Schaumburg, Martina, Lang, Elisabeth, Friede, Tim, Trenkwalder, Claudia

“…Objectives The objectives of this study were to investigate (1) the annual rate of progression of motor and cognitive symptoms and (2) baseline predictors of…”
Get full text

Evidence for immune system alterations in peripheral biological fluids in Parkinson's disease by Bartl, Michael, Xylaki, Mary, Bähr, Mathias, Weber, Sandrina, Trenkwalder, Claudia, Mollenhauer, Brit

“…Immune-related alterations in Parkinson's disease (PD) can be monitored by assessing peripheral biological fluids that show that specific inflammatory pathways…”
Get full text

Associated factors for REM sleep behavior disorder in Parkinson disease by SIXEL-DÖRING, Friederike, TRAUTMANN, Ellen, MOLLENHAUER, Brit, TRENKWALDER, Claudia

“…To investigate the frequency, phenomenology, and associated risk factors of REM sleep behavior disorder (RBD) in Parkinson disease (PD). An unselected cohort…”
Get full text

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates by Arotcarena, Marie-Laure, Dovero, Sandra, Prigent, Alice, Bourdenx, Mathieu, Camus, Sandrine, Porras, Gregory, Thiolat, Marie-Laure, Tasselli, Maddalena, Aubert, Philippe, Kruse, Niels, Mollenhauer, Brit, Trigo Damas, Ines, Estrada, Cristina, Garcia-Carrillo, Nuria, Vaikath, Nishant N, El-Agnaf, Omar M A, Herrero, Maria Trinidad, Vila, Miquel, Obeso, Jose A, Derkinderen, Pascal, Dehay, Benjamin, Bezard, Erwan

“…In Parkinson's disease, synucleinopathy is hypothesized to spread from the enteric nervous system, via the vagus nerve, to the CNS. Here, we compare, in baboon…”
Get full text

A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol by Gerdes, Christoph, Waal, Natalia, Offner, Thomas, Fornasiero, Eugenio F., Wender, Nora, Verbarg, Hannes, Manzini, Ivan, Trenkwalder, Claudia, Mollenhauer, Brit, Strohäker, Timo, Zweckstetter, Markus, Becker, Stefan, Rizzoli, Silvio O., Basmanav, Fitnat Buket, Opazo, Felipe

“…Aggregation and spreading of α-Synuclein (αSyn) are hallmarks of several neurodegenerative diseases, thus monitoring human αSyn (hαSyn) in animal models or…”
Get full text

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study by Mollenhauer, Brit, Dr, Locascio, Joseph J, PhD, Schulz-Schaeffer, Walter, MD, Sixel-Döring, Friederike, MD, Trenkwalder, Claudia, MD, Schlossmacher, Michael G, Dr

“…Summary Background Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy are brain disorders characterised by intracellular α-synuclein…”
Get full text

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies by Poggiolini, Ilaria, Gupta, Vandana, Lawton, Michael, Lee, Seoyun, El-Turabi, Aadil, Querejeta-Coma, Agustin, Trenkwalder, Claudia, Sixel-Döring, Friederike, Foubert-Samier, Alexandra, Pavy-Le Traon, Anne, Plazzi, Giuseppe, Biscarini, Francesco, Montplaisir, Jacques, Gagnon, Jean-François, Postuma, Ronald B, Antelmi, Elena, Meissner, Wassilios G, Mollenhauer, Brit, Ben-Shlomo, Yoav, Hu, Michele T, Parkkinen, Laura

“…Several studies have confirmed the α-synuclein real-time quaking-induced conversion (RT-QuIC) assay to have high sensitivity and specificity for Parkinson's…”
Get full text

Cerebrospinal fluid biomarker for Parkinson's disease: An overview by Maass, Fabian, Schulz, Isabel, Lingor, Paul, Mollenhauer, Brit, Bähr, Mathias

“…In Parkinson's disease (PD), there is a wide field of recent and ongoing search for useful biomarkers for early and differential diagnosis, disease monitoring…”
Get full text

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort by Simuni, Tanya, Caspell-Garcia, Chelsea, Coffey, Christopher S, Weintraub, Daniel, Mollenhauer, Brit, Lasch, Shirley, Tanner, Caroline M, Jennings, Danna, Kieburtz, Karl, Chahine, Lana M, Marek, Kenneth

“…ObjectiveTo examine the baseline prevalence and longitudinal evolution in non-motor symptoms (NMS) in a prospective cohort of, at baseline, patients with de…”
Get full text

Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease by Trezzi, Jean‐Pierre, Galozzi, Sara, Jaeger, Christian, Barkovits, Katalin, Brockmann, Kathrin, Maetzler, Walter, Berg, Daniela, Marcus, Katrin, Betsou, Fay, Hiller, Karsten, Mollenhauer, Brit

“…Objective: The purpose of this study was to profile cerebrospinal fluid (CSF) from early‐stage PD patients for disease‐related metabolic changes and to…”
Get full text

MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD-MCI by Litvan, Irene, Aarsland, Dag, Adler, Charles H., Goldman, Jennifer G., Kulisevsky, Jaime, Mollenhauer, Brit, Rodriguez-Oroz, Maria C., Tröster, Alexander I., Weintraub, Daniel

“…There is controversy regarding the definition and characteristics of mild cognitive impairment in Parkinson's disease. The Movement Disorder Society…”
Get full text

Biobanking of CSF: International standardization to optimize biomarker development by Teunissen, Charlotte E., Tumani, Hayrettin, Engelborghs, Sebastiaan, Mollenhauer, Brit

“…Cerebrospinal fluid (CSF) reflects pathophysiological aspects of neurological diseases, where neuroprotective strategies and biomarkers are urgently needed…”
Get full text

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease by Hertel, Johannes, Harms, Amy C., Heinken, Almut, Baldini, Federico, Thinnes, Cyrille C., Glaab, Enrico, Vasco, Daniel A., Pietzner, Maik, Stewart, Isobel D., Wareham, Nicholas J., Langenberg, Claudia, Trenkwalder, Claudia, Krüger, Rejko, Hankemeier, Thomas, Fleming, Ronan M.T., Mollenhauer, Brit, Thiele, Ines

“…Parkinson’s disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for the gut microbiome. Here, we integrate longitudinal…”
Get full text

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines by Litvan, Irene, Goldman, Jennifer G., Tröster, Alexander I., Schmand, Ben A., Weintraub, Daniel, Petersen, Ronald C., Mollenhauer, Brit, Adler, Charles H., Marder, Karen, Williams-Gray, Caroline H., Aarsland, Dag, Kulisevsky, Jaime, Rodriguez-Oroz, Maria C., Burn, David J., Barker, Roger A., Emre, Murat

“…Mild cognitive impairment is common in nondemented Parkinson's disease (PD) patients and may be a harbinger of dementia. In view of its importance, the…”
Get full text

Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease by Oliveira, Luis M. A., Gasser, Thomas, Edwards, Robert, Zweckstetter, Markus, Melki, Ronald, Stefanis, Leonidas, Lashuel, Hilal A., Sulzer, David, Vekrellis, Kostas, Halliday, Glenda M., Tomlinson, Julianna J., Schlossmacher, Michael, Jensen, Poul Henning, Schulze-Hentrich, Julia, Riess, Olaf, Hirst, Warren D., El-Agnaf, Omar, Mollenhauer, Brit, Lansbury, Peter, Outeiro, Tiago F.

“…With the advent of the genetic era in Parkinson’s disease (PD) research in 1997, α-synuclein was identified as an important player in a complex…”
Get full text