Search Results - "Mollazadeh, Shirin"

Structural and functional aspects of P-glycoprotein and its inhibitors by Mollazadeh, Shirin, Sahebkar, Amirhossein, Hadizadeh, Farzin, Behravan, Javad, Arabzadeh, Sepideh

“…P-glycoprotein (P-gp) is a member of ATP-binding cassette (ABC) superfamily which extrudes chemotherapeutic agents out of the cell. Suppression of this efflux…”
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Docking and QSAR Studies of 1,4-Dihydropyridine Derivatives as Anti- Cancer Agent by Mollazadeh, Shirin, Shamsara, Jamal, Iman, Maryam, Hadizadeh, Farzin

“…The multidrug resistance (MDR) of cancer cells has become a great barrier to the success of chemotherapy. In this study, quantitative structure activity…”
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Nano drug delivery systems: Molecular dynamic simulation by Mollazadeh, Shirin, Sahebkar, Amirhossein, Shahlaei, Mohsen, Moradi, Sajad

“…The therapeutic efficacy of drugs, especially hydrophobic anticancer agents, can be dramatically improved using advanced nanoplatforms. Recently, there has…”
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Concentration-dependent assembly of Bovine serum albumin molecules in the doxorubicin loading process: Molecular dynamics simulation by Mollazadeh, Shirin, Babaei, Saeed, Ostadhassan, Mehdi, Yazdian-Robati, Rezvan

“…Bovine serum albumin (BSA) is one of the most investigated proteins, exhibiting high potential for drug delivery. The positively charged doxorubicin (DOX) and…”
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Recent advances in the redox-responsive drug delivery nanoplatforms: A chemical structure and physical property perspective by Mollazadeh, Shirin, Mackiewicz, Marcin, Yazdimamaghani, Mostafa

“…Poor water solubility, off-target toxicity, and small therapeutic window are among major obstacles for the development of drug products. Redox-responsive drug…”
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New insight into the structural changes of apoferritin pores in the process of doxorubicin loading at an acidic pH: Molecular dynamics simulations by Mollazadeh, Shirin, Yazdimamaghani, Mostafa, Yazdian-Robati, Rezvan, Pirhadi, Somayeh

“…Apoferritin (APO-Fr) is one of the most investigated proteins proposed as an advanced structure for drug delivery systems. Herein, molecular dynamics…”
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Theoretical studies on 1,4-dihydropyridine derivatives as P-glycoprotein allosteric inhibitors: insights on symmetry and stereochemistry by Mollazadeh, Shirin, Hadizadeh, Farzin, Ferreira, Ricardo J.

“…P-glycoprotein (P-gp) is a key efflux pump involved in cellular multidrug resistance (MDR), lowering the concentration of many anticancer drugs in tumor cells…”
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Synthesis, in silico and in vitro studies of new 1,4-dihydropiridine derivatives for antitumor and P-glycoprotein inhibitory activity by Mollazadeh, Shirin, Sahebkar, Amirhossein, Kalalinia, Fatemeh, Behravan, Javad, Hadizadeh, Farzin

“…[Display omitted] Novel synthesized DHPs:•Increased accumulation of Rhodamin123 in resistant cell.•Had low cytotoxicity effect on normal cell & high…”
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Synthesis of Novel Asymmetrical 1,4‐Dihydropyridine Derivatives by Zenouz, Adeleh Moshtaghi, Oskuie, Mina Raisossadat, Mollazadeh, Shirin

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