A comprehensive review on frontotemporal dementia: its impact on language, speech and behavior

Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder defined by the selective deterioration of the frontal and temporal lobes of the brain. This comprehensive review explored the effect of FTD on language, speech, and behavior. Early symptoms include difficulty in word finding,...

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Bibliographic Details
Published in:Dementia & neuropsychologia Vol. 18; p. e20230072
Main Authors: Mollah, Sha Abbas, Nayak, Aditya, Barhai, Swapna, Maity, Uddip
Format: Journal Article
Language:English
Published: Brazil Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2024
Associação Neurologia Cognitiva e do Comportamento
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Summary:Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder defined by the selective deterioration of the frontal and temporal lobes of the brain. This comprehensive review explored the effect of FTD on language, speech, and behavior. Early symptoms include difficulty in word finding, reduced speech output, and comprehension deficits, often leading to aphasia. The study discussed the profound behavioral changes observed in FTD patients, including apathy, disinhibition, compulsive behaviors, and loss of empathy, the importance of an accurate and early diagnosis, and its challenges. We even reviewed the potential for targeted therapies and the essential role of multidisciplinary care in managing the language, speech, and behavioral aspects of FTD. By examining objective data and comprehensive research on the subject, this study offers valuable insights into FTD's profound effects on language, speech, and behavior, assisting in improved clinical management and potential therapeutic strategies for this devastating condition.
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Disclosure: The authors report no conflicts of interest.
ISSN:1980-5764
2764-4863
DOI:10.1590/1980-5764-DN-2023-0072