Search Results - "Moll, G.N."

LP2, a cyclic angiotensin-(1−7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice by Namsolleck, P., de Vries, L., Moll, G.N.

“…LP2 is a 4, 7 D, L lanthionine-stabilized analog of angiotensin-(1−7), with an N-terminal D-lysine, resistant to breakdown by peptidases. It is a specific…”
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To protect peptide pharmaceuticals against peptidases by Rink, R., Arkema-Meter, A., Baudoin, I., Post, E., Kuipers, A., Nelemans, S.A., Akanbi, M. Haas Jimoh, Moll, G.N.

“…Introduction: The major hurdle in the application and delivery of peptide pharmaceuticals is their rapid in vivo breakdown. Methods: We here combined two…”
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GRPR-selective PET imaging of prostate cancer using [18F]-lanthionine-bombesin analogs by Carlucci, G., Kuipers, A., Ananias, H.J.K., de Paula Faria, D., Dierckx, R.A.J.O., Helfrich, W., Rink, R., Moll, G.N., de Jong, I.J., Elsinga, P.H.

“…•The GRP receptor is overexpressed in several human cancer, including prostate cancer.•Full-length lanthionine-BBN analogs were used as PET agents for GRPR…”
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A biological stabilization technology for peptide drugs: enzymatic introduction of thioether-bridges by Moll, G.N., Kuipers, A., de Vries, L., Bosma, T., Rink, R.

“…The main limitation in the application of therapeutic peptides is their rapid degradation by proteolytic enzymes. Thioether-bridges in peptides confer strong…”
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Complementary and overlapping selectivity of the two-peptide bacteriocins plantaricin EF and JK by Moll, G.N, Akker, E. van den, Hauge, H.H, Nissen-Meyer, J, Nes, I.F, Konings, W.N, Driessen, A.J.M

“…Plantaricin EF and JK are both two-peptide bacteriocins produced by Lactobacillus plantarum C11. The mechanism of plantaricin EF and JK action was studied on…”
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Plantaricin A Is an Amphiphilic α-Helical Bacteriocin-like Pheromone Which Exerts Antimicrobial and Pheromone Activities through Different Mechanisms by Hauge, Håvard Hildeng, Mantzilas, Dimitris, Moll, Gert N, Konings, Wil N, Driessen, Arnold J. M, Eijsink, Vincent G. H, Nissen-Meyer, Jon

“…Production of bacteriocins by lactic acid bacteria is in some cases regulated by a quorum sensing mechanism that involves a secreted bacteriocin-like peptide…”
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Role of transmembrane pH gradient and membrane binding in nisin pore formation by Moll, G N, Clark, J, Chan, W C, Bycroft, B W, Roberts, G C, Konings, W N, Driessen, A J

“…Nisin is a cationic antimicrobial peptide that belongs to the group of lantibiotics. It is thought to form oligomeric pores in the target membrane by a…”
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lantibiotic nisin induces transmembrane movement of a fluorescent phospholipid by Moll, G.N, Konings, W.N, Driessen, A.J.M

“…Nisin is a pore-forming antimicrobial peptide. The capacity of nisin to induce transmembrane movement of a fluorescent phospholipid in lipid vesicles was…”
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Indirect introduction of long-chain pyrene-phosphatidylcholine into living cells by Moll, G N, el Yandouzi, E H, Zlatkine, P, Le Grimellec, C

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Selective internalization of choline-phospholipids in Plasmodium falciparum parasitized human erythrocytes by Simões, A P, Moll, G N, Slotboom, A J, Roelofsen, B, Op den Kamp, J A

“…We have incubated control and Plasmodium falciparum parasitized human erythrocytes with lipid vesicles containing radiolabeled long-chain phosphatidylcholine…”
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Plasmodium knowlesi induces alterations in phosphatidylcholine and phosphatidylethanolamine molecular species composition of parasitized monkey erythrocytes by Simões, A P, Moll, G N, Beaumelle, B, Vial, H J, Roelofsen, B, Op den Kamp, J A

“…Using high performance liquid chromatography and gas-liquid chromatography, we have characterized the phosphatidylcholine and phosphatidylethanolamine…”
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Phospholipid uptake by Plasmodium knowlesi infected erythrocytes by Moll, G.N., Vial, H.J., Ancelin, M.L., Op den Kamp, J.A.F., Roelofsen, B., van Deenen, L.L.M.

“…The uptake of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylserine (PS) in Plasmodium knowlesi infected erythrocytes has been…”
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