Search Results - "Molinaro, Mariadelfina"

Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology by Bergan, Stein, Brunet, Mercè, Hesselink, Dennis A., Johnson-Davis, Kamisha L., Kunicki, Paweł K., Lemaitre, Florian, Marquet, Pierre, Molinaro, Mariadelfina, Noceti, Ofelia, Pattanaik, Smita, Pawinski, Tomasz, Seger, Christoph, Shipkova, Maria, Swen, Jesse J., van Gelder, Teun, Venkataramanan, Raman, Wieland, Eberhard, Woillard, Jean-Baptiste, Zwart, Tom C., Barten, Markus J., Budde, Klemens, Dieterlen, Maja-Theresa, Elens, Laure, Haufroid, Vincent, Masuda, Satohiro, Millan, Olga, Mizuno, Tomoyuki, Moes, Dirk J. A. R., Oellerich, Michael, Picard, Nicolas, Salzmann, Linda, Tönshoff, Burkhard, van Schaik, Ron H. N., Vethe, Nils Tore, Vinks, Alexander A., Wallemacq, Pierre, Åsberg, Anders, Langman, Loralie J.

“…When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy, fixed doses were recommended by the manufacturer. Awareness of the…”
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Optimal Practice for Vancomycin Therapeutic Drug Monitoring: Position Statement From the Anti-infectives Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology by Reuter, Stephanie E., Stocker, Sophie L., Alffenaar, Jan-Willem C., Baldelli, Sara, Cattaneo, Dario, Jones, Graham, Koch, Birgit C. P., Kocic, Danijela, Mathew, Sumith K., Molinaro, Mariadelfina, Neely, Michael, Sandaradura, Indy, Marriott, Deborah J. E.

“…Individualization of vancomycin dosing based on therapeutic drug monitoring (TDM) data is known to improve patient outcomes compared with fixed or empirical…”
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Genetic Screening of Anderson-Fabry Disease in Probands Referred From Multispecialty Clinics by Favalli, Valentina, PhD, Disabella, Eliana, BD, Molinaro, Mariadelfina, BD, Tagliani, Marilena, BD, Scarabotto, Anna, BD, Serio, Alessandra, MD, Grasso, Maurizia, PhD, Narula, Nupoor, MD, Giorgianni, Carmela, BS, Caspani, Clelia, BD, Concardi, Monica, BS, Agozzino, Manuela, MD, Giordano, Calogero, BD, Smirnova, Alexandra, BD, Kodama, Takahide, MD, Giuliani, Lorenzo, BS, Antoniazzi, Elena, MD, Borroni, Riccardo G., MD, Vassallo, Camilla, MD, Mangione, Filippo, MD, Scelsi, Laura, MD, Ghio, Stefano, MD, Pellegrini, Carlo, MD, Zedde, Marialuisa, MD, Fancellu, Laura, MD, Sechi, GianPietro, MD, Ganau, Antonello, MD, Piga, Stefania, MD, Colucci, Annarita, MD, Concolino, Daniela, MD, Di Mascio, Maria Teresa, MD, Toni, Danilo, MD, Diomedi, Marina, MD, Rapezzi, Claudio, MD, Biagini, Elena, MD, Marini, Massimiliano, MD, Rasura, Maurizia, MD, Melis, Maurizio, MD, Nucera, Antonia, MD, Guidetti, Donata, MD, Mancuso, Michelangelo, MD, Scoditti, Umberto, MD, Cassini, Pamela, BD, Narula, Jagat, MD, Tavazzi, Luigi, MD, Arbustini, Eloisa, MD

“…Abstract Background Anderson-Fabry disease (AFD) is a rare X-linked lysosomal storage disease, caused by defects of the alpha-galactosidase A ( GLA ) gene. AFD…”
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Monitoring of Inosine Monophosphate Dehydrogenase Activity and Expression during the Early Period of Mycophenolate Mofetil Therapy in De Novo Renal Transplant Patients by Molinaro, Mariadelfina, Chiarelli, Laurent R., Biancone, Luigi, Castagneto, Marco, Boschiero, Luigi, Pisani, Francesco, Sabbatini, Massimo, Sandrini, Silvio, Arbustini, Eloisa, Tinelli, Carmine, Regazzi, Mario, Schena, Francesco P., Segoloni, Giuseppe P.

“…Measurement of inosine-monophosphate dehydrogenase (IMPDH) activity or gene expression was used as a further approach in pharmacokinetics (PK)/pharmacodynamic…”
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Inosine monophosphate dehydrogenase variability in renal transplant patients on long‐term mycophenolate mofetil therapy by Chiarelli, Laurent R., Molinaro, Mariadelfina, Libetta, Carmelo, Tinelli, Carmine, Cosmai, Laura, Valentini, Giovanna, Canton, Antonio Dal, Regazzi, Mario

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Mycophenolic acid (MPA) is a potent, selective and reversible inhibitor of inosine 5′‐monophosphate dehydrogenase…”
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Monoclonal Antibody Monitoring: Clinically Relevant Aspects, A Systematic Critical Review by Regazzi, Mario, Golay, Joseè, Molinaro, Mariadelfina

“…Monoclonal antibody (mAb) therapy does not usually lead to a clinical response in all patients and resistance may increase over time after repeated mAb…”
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Development and validation of a combined enzymatic-digestion/mass spectrometry assay for Tacrolimus quantitation in cardiac biopsies by Molinaro, Mariadelfina, Pellegrini, Carlo, Cattadori, Barbara, De Gregori, Simona

“…•A validated LC MS/MS assay for the quantitation of Tacrolimus in cardiac biopsies.•Optimization of samples preparation.•Method validation results in swine…”
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Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions by Elens, Laure, Langman, Loralie J., Hesselink, Dennis A., Bergan, Stein, Moes, Dirk Jan A.R., Molinaro, Mariadelfina, Venkataramanan, Raman, Lemaitre, Florian

“…COVID-19 is a novel infectious disease caused by the severe acute respiratory distress (SARS)-coronavirus-2 (SARS-CoV-2). Several therapeutic options are…”
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Posaconazole oral dose and plasma levels in pediatric hematology‐oncology patients by Vicenzi, Edoardo Bruno, Calore, Elisabetta, Decembrino, Nunzia, Berger, Massimo, Perruccio, Katia, Carraro, Francesca, Rossin, Sara, Putti, Maria Caterina, Molinaro, Mariadelfina, Tridello, Gloria, Cesaro, Simone

“…Background Posaconazole is a triazole with limited pharmacokinetic information in children. This study assessed the correlation between posaconazole oral…”
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Human Genetic Variability Contributes to Postoperative Morphine Consumption by De Gregori, Manuela, Diatchenko, Luda, Ingelmo, Pablo M, Napolioni, Valerio, Klepstad, Pal, Belfer, Inna, Molinaro, Valeria, Garbin, Giulia, Ranzani, Guglielmina N, Alberio, Giovanni, Normanno, Marco, Lovisari, Federica, Somaini, Marta, Govoni, Stefano, Mura, Elisa, Bugada, Dario, Niebel, Thekla, Zorzetto, Michele, De Gregori, Simona, Molinaro, Mariadelfina, Fanelli, Guido, Allegri, Massimo

“…High interindividual variability in postoperative opioid consumption is related to genetic and environmental factors. We tested the association between…”
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Optimal Practice for Vancomycin Therapeutic Drug Monitoring: Position Statement from the Anti-Infectives Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) by Reuter, Stephanie E, Stocker, Sophie L, Alffenaar, Jan-Willem C, Baldelli, Sara, Cattaneo, Dario, Jones, Graham, Koch, Birgit CP, Kocic, Danijela, Mathew, Sumith K, Molinaro, Mariadelfina, Neely, Michael, Sandaradura, Indy, Marriott, Deborah JE

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High Performance Liquid Chromatography–Tandem Mass Spectrometry Method for Simultaneous Quantification of Caspofungin, Anidulafungin and Micafungin in Human Plasma for Feasible Applications in Pediatric Haematology/Oncology by Ventura, Marianna, Michelini, Roberta, Decembrino, Nunzia, Molinaro, Mariadelfina, Zecca, Marco, De Gregori, Simona

“…A liquid chromatography–tandem mass spectrometry method was validated for the simultaneous quantification of anidulafungin (ANF), caspofungin (CSF) and…”
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Hydroxychloroquine Blood Concentrations Can Be Clinically Relevant Also After Drug Discontinuation by De Gregori, Simona, Falaschi, Francesco, Ballesio, Alessia, Fusco, Alessandra, Cremonte, Elisa, Canta, Roberta, Sabatini, Umberto, Molinaro, Mariadelfina, Soffiantini, Carlo, Nardone, Alba, Vicentini, Alessandro, De Silvestri, Annalisa, Di Sabatino, Antonio

“…Background and Objective Hydroxychloroquine was widely used during the severe acute respiratory syndrome coronavirus 2 pandemic as an antiviral drug. Most…”
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Falsely elevated whole blood cyclosporine concentrations measured by an immunoassay with automated pretreatment by Bartoli, Antonella, Molinaro, Mariadelfina, Visai, Livia

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Bioequivalence of a New Oral Levosulpiride Formulation Compared With a Standard One in Healthy Volunteers by De Gregori, Simona, Cipollina, Laura, De Silvestri, Annalisa, Ventura, Marianna, Michelini, Roberta, Morosini, Monica, Montagna, Michela, Tinelli, Carmine, Regazzi, Mario, Molinaro, Mariadelfina, Imberti, Roberto

“…A monocentric, single-dose, open-label, 2-way, crossover randomized study was conducted by the San Matteo Phase I Clinical Trial Unit and Experimental Therapy…”
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Efficacy of intraventricular amikacin treatment in pan-resistant Pseudomonas aeruginosa postsurgical meningitis by Molinaro, Mariadelfina, Morelli, Paola, De Gregori, Manuela, De Gregori, Simona, Giardini, Ilaria, Tordato, Federica, Monzillo, Vincenzina, Pocaterra, Daria, Casari, Erminia

“…We describe a case of pan-resistant postsurgical meningitis associated with the presence of an external ventricular device. We changed therapy twice; finally,…”
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In vitro and in vivo quantification of chloroprocaine release from an implantable device in a piglet postoperative pain model by De Gregori, Simona, De Gregori, Manuela, Bloise, Nora, Bugada, Dario, Molinaro, Mariadelfina, Filisetti, Claudia, Allegri, Massimo, Schatman, Michael E, Cobianchi, Lorenzo

“…The pharmacokinetic properties and clinical advantages of the local anesthetic chloroprocaine are well known. Here, we studied the pharmacokinetic profile of a…”
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Clinically significant drug interactions with cyclosporin : an update by CAMPANA, C, REGAZZI, M. B, BUGGIA, I, MOLINARO, M

“…Since its approval in 1983 for immunosuppressive therapy in patients undergoing organ and bone marrow transplants, cyclosporin has had a major impact on organ…”
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Effects of Recombinant Growth Hormone on Visceral Fat Accumulation: Pilot Study in Human Immunodeficiency Virus-Infected Adolescents by Viganò, Alessandra, Mora, Stefano, Manzoni, Paola, Schneider, Laura, Beretta, Silvia, Molinaro, Mariadelfina, di Natale, Berardo, Brambilla, Paolo

“…Context: Recombinant human GH (rhGH) reduces excess accumulation of intraabdominal adipose tissue (IAT) in lipodystrophic HIV-infected adults, whereas data in…”
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Clinical pharmacokinetics of tacrolimus in heart transplant recipients by REGAZZI, M. B, RINALDI, M, MOLINARO, M, PELLEGRINI, C, CALVI, M, ARBUSTINI, E, BELLOTTI, E, BASCAPE, V, MARTINELLI, L, VIGANO, M

“…We report pharmacokinetic data on tacrolimus in 14 heart transplant patients (2 women, 12 men). The median age and the median body weight were 55.5 years…”
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