Search Results - "Molinaro, Alyssa M."

In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians by Molinaro, Alyssa M, Pearson, Bret J

“…The planarian Schmidtea mediterranea is a master regenerator with a large adult stem cell compartment. The lack of transgenic labeling techniques in this…”
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Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation by Swapna, Lakshmipuram Seshadri, Molinaro, Alyssa M, Lindsay-Mosher, Nicole, Pearson, Bret J, Parkinson, John

“…In the Lophotrochozoa/Spiralia superphylum, few organisms have as high a capacity for rapid testing of gene function and single-cell transcriptomics as the…”
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The BAF chromatin remodeling complex licenses planarian stem cells access to ectodermal and mesodermal cell fates by Wiggans, Mallory, Zhu, Shu Jun, Molinaro, Alyssa M, Pearson, Bret J

“…Abstract Background The flatworm planarian, Schmidtea mediterranea , has a large population of adult stem cells (ASCs) that replace any cell type during tissue…”
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Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain by Currie, Ko W, Molinaro, Alyssa M, Pearson, Bret J

“…The asexual freshwater planarian is a constitutive adult, whose central nervous system (CNS) is in a state of constant homeostatic neurogenesis. However, very…”
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An RNA/DNA-Based Flow Cytometry Approach for Isolating Slow-Cycling Stem Cells by Lindsay-Mosher, Nicole, Molinaro, Alyssa M, Pearson, Bret J

“…Flow cytometry methods for sorting specific populations of cells based on fluorescence or physical properties have been a widely used technique for decades…”
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Identification of TOR-responsive slow-cycling neoblasts in planarians by Molinaro, Alyssa M, Lindsay-Mosher, Nicole, Pearson, Bret J

“…Epimorphic regeneration commonly relies on the activation of reserved stem cells to drive new cell production. The planarian Schmidtea mediterranea is among…”
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FOX and ETS family transcription factors regulate the pigment cell lineage in planarians by He, Xinwen, Lindsay-Mosher, Nicole, Li, Yan, Molinaro, Alyssa M, Pellettieri, Jason, Pearson, Bret J

“…Many pigment cells acquire unique structural properties and gene expression profiles during animal development. The underlying differentiation pathways have…”
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SoxB1 Activity Regulates Sensory Neuron Regeneration, Maintenance, and Function in Planarians by Ross, Kelly G, Molinaro, Alyssa M, Romero, Celeste, Dockter, Brian, Cable, Katrina L, Gonzalez, Karla, Zhang, Siqi, Collins, Eva-Maria S, Pearson, Bret J, Zayas, Ricardo M

“…SoxB1 genes play fundamental roles in neurodevelopmental processes and maintaining stem cell multipotency, but little is known about their function in…”
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The planarian TCF/LEF factor Smed-tcf1 is required for the regeneration of dorsal-lateral neuronal subtypes by Brown, David D.R., Molinaro, Alyssa M., Pearson, Bret J.

“…The adult brain of the planarian Schmidtea mediterranea (a freshwater flatworm) is a dynamic structure with constant cell turnover as well as the ability to…”
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Myths vs. FACS: what do we know about planarian stem cell lineages? by Molinaro, Alyssa M, Pearson, Bret J

“…Historically, planarian neoblasts were thought to be a homogeneous population of pluripotent stem cells; however, recent population and single-cell level…”
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An optimized QF-binary expression system for use in zebrafish by Burgess, Jason, Burrows, Jeffrey T., Sadhak, Roshan, Chiang, Sharon, Weiss, Alex, D’Amata, Cassandra, Molinaro, Alyssa M., Zhu, Shujun, Long, Michael, Hu, Chun, Krause, Henry M., Pearson, Bret J.

“…The zebrafish model organism has been of exceptional utility for the study of vertebrate development and disease through the application of tissue-specific…”
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