Search Results - "Molina Cerrillo, Javier"
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1
Tumor‐associated macrophages: “Good cop‐bad cop”
Published in Cancer (01-06-2019)Get full text
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Clinical features and response to immune combinations in patients with renal cell carcinoma and sarcomatoid de-differentiation (ARON-1 study)
Published in International journal of cancer (01-12-2024)“…Metastatic renal cell carcinoma (mRCC) carrying sarcomatoid features (sRCC) has aggressive biology and poor prognosis. First-line immunotherapy (IO)-based…”
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The PALBONET Trial: A Phase II Study of Palbociclib in Metastatic Grade 1 and 2 Pancreatic Neuroendocrine Tumors (GETNE‐1407)
Published in The oncologist (Dayton, Ohio) (01-09-2020)“…Lessons Learned Palbociclib demonstrated no detectable activity in molecularly unselected and heavily pretreated patients with advanced grade 1/2 pancreatic…”
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Inhibition of Serotonin Synthesis May Have Antitumor Activity? Long‐Term Efficacy in a Patient with Gastrointestinal Neuroendocrine Tumor
Published in The oncologist (Dayton, Ohio) (01-07-2019)“…In this article, we propose, based on a clinical case, the potential antitumor effect related to the inhibition of serotonin in neuroendocrine tumors (NETs)…”
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Targeting Tyrosine kinases in Renal Cell Carcinoma: "New Bullets against Old Guys"
Published in International journal of molecular sciences (17-04-2019)“…Clear cell renal cell carcinoma (ccRCC) is the seventh most frequently diagnosed tumor in adults in Europe and represents approximately 2.5% of cancer deaths…”
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Tyrosine Kinase Receptors in Oncology
Published in International journal of molecular sciences (12-11-2020)“…Tyrosine kinase receptors (TKR) comprise more than 60 molecules that play an essential role in the molecular pathways, leading to cell survival and…”
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Sunitinib and Evofosfamide (TH‐302) in Systemic Treatment‐Naïve Patients with Grade 1/2 Metastatic Pancreatic Neuroendocrine Tumors: The GETNE‐1408 Trial
Published in The oncologist (Dayton, Ohio) (01-11-2021)“…Background Sunitinib (SUN)‐induced hypoxia within the tumor could promote the activation of the prodrug evofosfamide (EVO), locally releasing the cytotoxic DNA…”
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Targeting Angiogenesis in Pancreatic Neuroendocrine Tumors: Resistance Mechanisms
Published in International journal of molecular sciences (08-10-2019)“…Despite being infrequent tumors, the incidence and prevalence of pancreatic neuroendocrine tumors (P-NETs) has been rising over the past few decades. In recent…”
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Limited T cell response to SARS-CoV-2 mRNA vaccine among patients with cancer receiving different cancer treatments
Published in European journal of cancer (1990) (01-05-2022)“…Patients with cancer (PC) are at high risk of acquiring COVID-19 and can develop more serious complications. Deeper understanding of vaccines immunogenicity in…”
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Inhibition of Peripheral Synthesis of Serotonin as a New Target in Neuroendocrine Tumors
Published in The oncologist (Dayton, Ohio) (01-06-2016)“…The carcinoid syndrome represents a set of signs and symptoms associated with neuroendocrine tumors (NETs) that occur primarily when metastases are developed…”
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Novel Tyrosine Kinase Targets in Urothelial Carcinoma
Published in International journal of molecular sciences (13-01-2021)“…Urothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the…”
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Current and Future Role of Tyrosine Kinases Inhibition in Thyroid Cancer: From Biology to Therapy
Published in International journal of molecular sciences (13-07-2020)“…Thyroid cancer represents a heterogenous disease whose incidence has increased in the last decades. Although three main different subtypes have been described,…”
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Immunotherapy in Adrenocortical Carcinoma: Predictors of Response, Efficacy, Safety, and Mechanisms of Resistance
Published in Biomedicines (16-03-2021)“…Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with limited treatment options in the advanced stages. Immunotherapy offers hope for altering the…”
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Novel Molecular Characterization of Colorectal Primary Tumors Based on miRNAs
Published in Cancers (11-03-2019)“…microRNAs (miRNA) expression in colorectal (CR) primary tumours can facilitate a more precise molecular characterization. We identified and validated a miRNA…”
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May Ibrutinib Have Activity in Respiratory Complications by SARS-CoV-2? Clinical Experience in a Patient with Chronic Lymphocytic Leukemia
Published in Healthcare (Basel) (01-01-2021)“…COVID-19 is affecting many countries all around the world. Unfortunately, no treatment has already been approved for the management of patients infected by…”
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The effect of medical and urologic disorders on the survival of patients with metastatic castration resistant prostate cancer treated with abiraterone or enzalutamide
Published in Therapeutic advances in urology (2021)“…Introduction: Androgenic deprivation therapies have been linked to the development of metabolic syndrome (MS) and cardiovascular diseases, which may lead to a…”
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Primary Neuroendocrine Tumor of the Parotid Gland: A Case Report and a Comprehensive Review of a Rare Entity
Published in Case reports in otolaryngology (01-01-2016)“…Neuroendocrine tumors (NETs) comprise a heterogeneous group of malignancies from cells derived from the neural crest with neuroendocrine differentiation…”
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Complete remissions following immunotherapy or immuno-oncology combinations in cancer patients: the MOUSEION-03 meta-analysis
Published in Cancer Immunology, Immunotherapy (01-06-2023)“…Background Immunotherapy has determined unprecedented long-term responses in several hematological and solid tumors. In the MOUSEION-03 study, we conducted a…”
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Targeting HIF-2 α in clear cell renal cell carcinoma: A promising therapeutic strategy
Published in Critical reviews in oncology/hematology (01-03-2017)“…Highlights • Antiangiogenic therapies are key therapeutic agents in ccRCC. • The evidence suggests that HIF-2α subunit has a central role in ccRCC over HIF-1α…”
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