Search Results - "Molina, Thierry J."

Frequent engagement of RelB activation is critical for cell survival in multiple myeloma by Cormier, Françoise, Monjanel, Hélène, Fabre, Claire, Billot, Katy, Sapharikas, Elène, Chereau, Fanny, Bordereaux, Didier, Molina, Thierry J, Avet-Loiseau, Hervé, Baud, Véronique

“…The NF-κB family of transcription factors has emerged as a key player in the pathogenesis of multiple myeloma (MM). NF-κB is activated by at least two major…”
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Immuno–Fluorescence In Situ Hybridization Index Predicts Survival in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP: A GELA Study by COPIE-BERGMAN, Christiane, GAULARD, Philippe, EMILE, Jean-François, BANHAM, Alison H, MOUNIER, Nicolas, GISSELBRECHT, Christian, FEUGIER, Pierre, COIFFIER, Bernand, MOLINA, Thierry J, LEROY, Karen, BRIERE, Josette, BAIA, Maryse, JAIS, Jean-Philippe, SALLES, Gilles A, BERGER, Françoise, HAIOUN, Corinne, TILLY, Herve

“…To evaluate the prognostic value of cell of origin immunohistochemical markers and BCL2, BCL6, and c-MYC translocations in a homogeneous cohort of patients…”
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c-Rel Is the Pivotal NF-κB Subunit in Germinal Center Diffuse Large B-Cell Lymphoma: A LYSA Study by Faumont, Nathalie, Taoui, Oussama, Collares, Davi, Jais, Jean-Philippe, Leroy, Karen, Prévaud, Léa, Jardin, Fabrice, Molina, Thierry J, Copie-Bergman, Christiane, Petit, Barbara, Gourin, Marie-Pierre, Bordessoule, Dominique, Troutaud, Danielle, Baud, Véronique, Feuillard, Jean

“…Relationships between c-Rel and GCB-DLBCLs remain unclear. We found that strong c-Rel DNA-binding activity was mostly found in GCBs on two independent series…”
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Gene expression profiling of gray zone lymphoma by Sarkozy, Clémentine, Chong, Lauren, Takata, Katsuyoshi, Chavez, Elizabeth A., Miyata-Takata, Tomoko, Duns, Gerben, Telenius, Adèle, Boyle, Merrill, Slack, Graham W., Laurent, Camille, Farinha, Pedro, Molina, Thierry J., Copie-Bergman, Christiane, Damotte, Diane, Salles, Gilles A., Mottok, Anja, Savage, Kerry J., Scott, David W., Traverse-Glehen, Alexandra, Steidl, Christian

“…Gray zone lymphoma (GZL), a B-cell lymphoma with features intermediate between large B-cell lymphoma (LBCL) and classic Hodgkin lymphoma (cHL), is a rare and…”
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A specific molecular signature in SARS-CoV-2-infected kidney biopsies by Isnard, Pierre, Vergnaud, Paul, Garbay, Serge, Jamme, Matthieu, Eloudzeri, Maeva, Karras, Alexandre, Anglicheau, Dany, Galantine, Valérie, Jalal Eddine, Arwa, Gosset, Clément, Pourcine, Franck, Zarhrate, Mohammed, Gibier, Jean-Baptiste, Rensen, Elena, Pietropaoli, Stefano, Barba-Spaeth, Giovanna, Duong-Van-Huyen, Jean-Paul, Molina, Thierry J, Mueller, Florian, Zimmer, Christophe, Pontoglio, Marco, Terzi, Fabiola, Rabant, Marion

“…Acute kidney injury is one of the most important complications in patients with COVID-19 and is considered a negative prognostic factor with respect to patient…”
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Critical role of monocytes to support normal B cell and diffuse large B cell lymphoma survival and proliferation by Mueller, Chris G., Boix, Charlotte, Kwan, Wing‐Hong, Daussy, Cécile, Fournier, Emilie, Fridman, Wolf H., Molina, Thierry J.

“…Large B cell lymphomas can comprise numerous CD14+ cells in the tumor stroma, which raises the question of whether monocytes can support B cell survival and…”
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Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations by Jeremiah, Nadia, Neven, Bénédicte, Gentili, Matteo, Callebaut, Isabelle, Maschalidi, Sophia, Stolzenberg, Marie-Claude, Goudin, Nicolas, Frémond, Marie-Louis, Nitschke, Patrick, Molina, Thierry J, Blanche, Stéphane, Picard, Capucine, Rice, Gillian I, Crow, Yanick J, Manel, Nicolas, Fischer, Alain, Bader-Meunier, Brigitte, Rieux-Laucat, Frédéric

“…Innate immunity to viral infection involves induction of the type I IFN response; however, dysfunctional regulation of this pathway leads to inappropriate…”
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Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study by Dubois, Sydney, Viailly, Pierre-Julien, Mareschal, Sylvain, Bohers, Elodie, Bertrand, Philippe, Ruminy, Philippe, Maingonnat, Catherine, Jais, Jean-Philippe, Peyrouze, Pauline, Figeac, Martin, Molina, Thierry J, Desmots, Fabienne, Fest, Thierry, Haioun, Corinne, Lamy, Thierry, Copie-Bergman, Christiane, Brière, Josette, Petrella, Tony, Canioni, Danielle, Fabiani, Bettina, Coiffier, Bertrand, Delarue, Richard, Peyrade, Frédéric, Bosly, André, André, Marc, Ketterer, Nicolas, Salles, Gilles, Tilly, Hervé, Leroy, Karen, Jardin, Fabrice

“…Next-generation sequencing (NGS) has detailed the genomic characterization of diffuse large B-cell lymphoma (DLBCL) by identifying recurrent somatic mutations…”
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Diagnosis-to-Treatment Interval Is an Important Clinical Factor in Newly Diagnosed Diffuse Large B-Cell Lymphoma and Has Implication for Bias in Clinical Trials by Maurer, Matthew J, Ghesquières, Hervé, Link, Brian K, Jais, Jean-Philippe, Habermann, Thomas M, Thompson, Carrie A, Haioun, Corinne, Allmer, Cristine, Johnston, Patrick B, Delarue, Richard, Micallef, Ivana N, Peyrade, Frederic, Inwards, David J, Ketterer, Nicolas, Farooq, Umar, Fitoussi, Olivier, Macon, William R, Molina, Thierry J, Syrbu, Sergei, Feldman, Andrew L, Slager, Susan L, Weiner, George J, Ansell, Stephen M, Cerhan, James R, Salles, Gilles A, Witzig, Thomas E, Tilly, Hervé, Nowakowski, Grzegorz S

“…Purpose Selection bias in clinical trials has consequences for scientific validity and applicability of study results to the general population. There is…”
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Resistance of B-Cell Lymphomas to CAR T-Cell Therapy Is Associated With Genomic Tumor Changes Which Can Result in Transdifferentiation by Laurent, Camille, Syrykh, Charlotte, Hamon, Maxime, Adélaïde, José, Guille, Arnaud, Escudié, Frederic, Jalowicki, Gael, Fina, Frederic, Bardet, Alexandre, Mescam, Lenaïg, Molina, Thierry J., Dartigues, Peggy, Parrens, Marie, Sujobert, Pierre, Besson, Caroline, Birnbaum, Daniel, Xerri, Luc

“…Despite the impressive efficacy of chimeric antigen receptor (CAR) T-cell therapy (CART) in B-cell non-Hodgkin lymphomas, durable responses are uncommon. The…”
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Composite mantle cell and follicular lymphoma. A case report by Ilgenfritz, Raquel B., MD, Le Tourneau, Agnès, MD, Arborio, Michel, MD, Molina, Thierry J., MD, PhD, Diebold, Jacques, MD, Damotte, Diane, MD, PhD, Audouin, Josée, MD

“…Summary We describe the association of 2 types of small B-cell lymphomas with different morphologic and immunophenotype patterns inside the same lymph node…”
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Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P-Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases by Dubois, Sydney, Viailly, Pierre-Julien, Bohers, Elodie, Bertrand, Philippe, Ruminy, Philippe, Marchand, Vinciane, Maingonnat, Catherine, Mareschal, Sylvain, Picquenot, Jean-Michel, Penther, Dominique, Jais, Jean-Philippe, Tesson, Bruno, Peyrouze, Pauline, Figeac, Martin, Desmots, Fabienne, Fest, Thierry, Haioun, Corinne, Lamy, Thierry, Copie-Bergman, Christiane, Fabiani, Bettina, Delarue, Richard, Peyrade, Frédéric, André, Marc, Ketterer, Nicolas, Leroy, Karen, Salles, Gilles, Molina, Thierry J, Tilly, Hervé, Jardin, Fabrice

“…mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of activated B-cell like (ABC) diffuse large B-cell lymphoma…”
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International reproducibility study of thymic epithelial tumors staging: pT stage is an issue. proposals for improvement. A RYTHMIC/ITMIG study by Molina, Thierry J., Roden, Anja C., Szolkowska, Malgorzata, Shimizu, Shigeki, Moreira, Andre L., Chalabreysse, Lara, Besse, Benjamin, de Montpréville, Vincent, Marom, Edith M., Detterbeck, Frank, Girard, Nicolas, Nicholson, Andrew G., Marx, Alexander

“…•Reproducibility between expert pathologists to evaluate pT of thymomas is problematic.•Thymomas may grow with their “capsule” adhering to rather than invading…”
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CD14 and CD169 expression in human lymph nodes and spleen: specific expansion of CD14 +CD169 − monocyte-derived cells in diffuse large B-cell lymphomas by Marmey, Béatrice, Boix, Charlotte, Barbaroux, Jean-Baptiste, Dieu-Nosjean, Marie-Caroline, Diebold, Jacques, Audouin, Josée, Fridman, Wolf-Herman, Mueller, Chris G.F., Molina, Thierry J.

“…The mononuclear phagocyte system of human lymphoid tissue comprises macrophages and dendritic cells (DCs). The heterogeneity of the non-DC mononuclear…”
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Impact of expert pathologic review of thymic epithelial tumours on diagnosis and management in a real-life setting: A RYTHMIC study by Molina, Thierry J., Bluthgen, Maria V., Chalabreysse, Lara, de Montpréville, Vincent T., de Muret, Anne, Dubois, Romain, Hofman, Véronique, Lantuejoul, Sylvie, le Naoures, Cécile, Mansuet-Lupo, Audrey, Parrens, Marie, Piton, Nicolas, Rouquette, Isabelle, Secq, Véronique, Girard, Nicolas, Marx, Alexander, Besse, Benjamin

“…Classification of thymic epithelial tumours (TETs) is known to be challenging; however, the level of discordances at a nationwide level between initial and…”
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Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans by Le, Thuy-Linh, Galmiche, Louise, Levy, Jonathan, Suwannarat, Pim, Hellebrekers, Debby Mei, Morarach, Khomgrit, Boismoreau, Franck, Theunissen, Tom Ej, Lefebvre, Mathilde, Pelet, Anna, Martinovic, Jelena, Gelot, Antoinette, Guimiot, Fabien, Calleroz, Amanda, Gitiaux, Cyril, Hully, Marie, Goulet, Olivier, Chardot, Christophe, Drunat, Severine, Capri, Yline, Bole-Feysot, Christine, Nitschké, Patrick, Whalen, Sandra, Mouthon, Linda, Babcock, Holly E, Hofstra, Robert, de Coo, Irenaeus Fm, Tabet, Anne-Claude, Molina, Thierry J, Keren, Boris, Brooks, Alice, Smeets, Hubert Jm, Marklund, Ulrika, Gordon, Christopher T, Lyonnet, Stanislas, Amiel, Jeanne, Bondurand, Nadège

“…Hirschsprung disease (HSCR) is the most frequent developmental anomaly of the enteric nervous system, with an incidence of 1 in 5000 live births. Chronic…”
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Marginal Zone Lymphomas With Plasmacytic Differentiation and Related Disorders by MOLINA, Thierry J, PEI LIN, SWERDLOW, Steven H, COOK, James R

“…Marginal zone lymphomas of all types (nodal, splenic, and extranodal mucosa-associated lymphoid tissue [MALT]) may show plasmacytic differentiation…”
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Immune signatures distinguish frequent from non‐frequent exacerbators among children with severe asthma by Adel‐Patient, Karine, Grauso, Marta, Abou‐Taam, Rola, Guillon, Blanche, Dietrich, Céline, Machavoine, François, Garcelon, Nicolas, Briard, Mélanie, Faour, Hassan, Neuraz, Antoine, Delacourt, Christophe, Molina, Thierry J., Leite‐de‐Moraes, Maria, Lezmi, Guillaume

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Through the Glass Ceiling by Tilly, Hervé, Salles, Gilles, Molina, Thierry J, Casasnovas, René-Olivier, Morschhauser, Franck, Coiffier, Bertrand

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Lymphoplasmacytic Lymphoma and Other Non-Marginal Zone Lymphomas With Plasmacytic Differentiation by PEI LIN, MOLINA, Thierry J, COOK, James R, SWERDLOW, Steven H

“…Small B-cell lymphomas with plasmacytic differentiation frequently present diagnostic challenges. Session 3 of the 2009 Society for Hematopathology/European…”
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