Search Results - "Molica, Carmen"
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Optimizing the risk stratification of astrocytic tumors by applying the cIMPACT-NOW Update 3 signature: real-word single center experience
Published in Scientific reports (16-11-2023)“…Our work reports implementation of a useful genetic diagnosis for the clinical managment of patients with astrocytic tumors. We investigated 313 prospectively…”
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Corrigendum: A novel BRCA1 splicing variant detected in an early onset triple-negative breast cancer patient additionally carrying a pathogenic variant in ATM: a case report
Published in Frontiers in oncology (23-10-2023)“…[This corrects the article DOI: 10.3389/fonc.2023.1102184.]…”
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A novel BRCA1 splicing variant detected in an early onset triple-negative breast cancer patient additionally carrying a pathogenic variant in ATM : A case report
Published in Frontiers in oncology (21-03-2023)“…The widespread adoption of gene panel testing for cancer predisposition is leading to the identification of an increasing number of individuals with clinically…”
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New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma
Published in Acta neuropathologica communications (25-08-2020)“…Abstract The catalytic activity of human Telomerase Reverse Transcriptase (TERT) compensates for the loss of telomere length, eroded during each cell cycle, to…”
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Sensitivity to Immune Checkpoint Blockade in Advanced Non-Small Cell Lung Cancer Patients with EGFR Exon 20 Insertion Mutations
Published in Genes (30-04-2021)“…Besides platinum-based chemotherapy, no established treatment option exists for advanced non-small-cell lung cancer (NSCLC) patients with exon 20 (Ex20ins)…”
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Prevalence and Spectrum of BRCA Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study
Published in Genes (12-08-2020)“…Hereditary breast and ovarian cancers are mainly linked to variants in /2 genes. Recently, data has shown that identification of variants has an immediate…”
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KRAS mutational status and sensitivity to a reversible epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) in EGFR wild type (WT) advanced non-small cell lung cancer (NSCLC) patients (pts)
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e18023 Background: Treatment with a reversible EGFR-TKI may benefit pts with EGFR WT advanced NSCLC, though to a much lesser extent than pts…”
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Response to afatinib in patients with advanced NSCLC previously treated with reversible EGFR inhibitors in a mono-institutional experience
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e18101 Background: All mutated non-small cell lung cancer (NSCLC) patients (pts) previously treated with an EGFR reversibile inhibitor, develop,…”
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A novel BRCA1 splicing variant detected in an early onset triple-negative breast cancer patient additionally carrying a pathogenic variant in ATM: A case report
Published in Frontiers in oncology (01-01-2023)“…The widespread adoption of gene panel testing for cancer predisposition is leading to the identification of an increasing number of individuals with clinically…”
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