Search Results - "Molgó, J."

Regulation of autophagy by the inositol trisphosphate receptor by Criollo, A, Maiuri, M C, Tasdemir, E, Vitale, I, Fiebig, A A, Andrews, D, Molgó, J, Díaz, J, Lavandero, S, Harper, F, Pierron, G, di Stefano, D, Rizzuto, R, Szabadkai, G, Kroemer, G

“…The reduction of intracellular 1,4,5-inositol trisphosphate (IP(3)) levels stimulates autophagy, whereas the enhancement of IP(3) levels inhibits autophagy…”
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IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2 by Akl, H, Monaco, G, La Rovere, R, Welkenhuyzen, K, Kiviluoto, S, Vervliet, T, Molgó, J, Distelhorst, C W, Missiaen, L, Mikoshiba, K, Parys, J B, De Smedt, H, Bultynck, G

“…Disrupting inositol 1,4,5-trisphosphate (IP 3 ) receptor (IP 3 R)/B-cell lymphoma 2 (Bcl-2) complexes using a cell-permeable peptide (stabilized TAT-fused IP 3…”
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Outcome of acetylcholinesterase deficiency for neuromuscular functioning by Mouisel, E., Blondet, B., Escourrou, P., Chatonnet, A., Molgó, J., Ferry, A.

“…Acetylcholinesterase (AChE) plays an essential role in neuromuscular transmission, therefore it is surprising that AChE knockout (KO) mice could live to the…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α 1A ‐adrenoceptor by Quinton, L, Girard, E, Maiga, A, Rekik, M, Lluel, P, Masuyer, G, Larregola, M, Marquer, C, Ciolek, J, Magnin, T, Wagner, R, Molgó, J, Thai, R, Fruchart‐Gaillard, C, Mourier, G, Chamot‐Rooke, J, Ménez, A, Palea, S, Servent, D, Gilles, N

“…Background and purpose:  Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G‐protein coupled…”
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The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 by Vicencio, J M, Ortiz, C, Criollo, A, Jones, A W E, Kepp, O, Galluzzi, L, Joza, N, Vitale, I, Morselli, E, Tailler, M, Castedo, M, Maiuri, M C, Molgó, J, Szabadkai, G, Lavandero, S, Kroemer, G

“…The inositol 1,4,5-trisphosphate receptor (IP 3 R) is a major regulator of apoptotic signaling. Through interactions with members of the Bcl-2 family of…”
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Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress by Chiong, M, Parra, V, Eisner, V, Ibarra, C, Maldonado, C, Criollo, A, Bravo, R, Quiroga, C, Contreras, A, Vicencio, J M, Cea, P, Bucarey, J L, Molgó, J, Jaimovich, E, Hidalgo, C, Kroemer, G, Lavandero, S

“…Hyperosmotic stress promotes rapid and pronounced apoptosis in cultured cardiomyocytes. Here, we investigated if Ca(2+) signals contribute to this response…”
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Glycerotoxin stimulates neurotransmitter release from N‐type Ca2+ channel expressing neurons by Schenning, Mitja, Proctor, Dustin T., Ragnarsson, Lotten, Barbier, Julien, Lavidis, Nickolas A., Molgó, Jordi J., Zamponi, Gerald W., Schiavo, Giampietro, Meunier, Frederic A.

“…Glycerotoxin (GLTx) is capable of stimulating neurotransmitter release at the frog neuromuscular junction by directly interacting with N‐type Ca2+ (Cav2.2)…”
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A New ω-Conotoxin That Targets N-Type Voltage-Sensitive Calcium Channels with Unusual Specificity by Favreau, Philippe, Gilles, Nicolas, Lamthanh, Hung, Bournaud, Roland, Shimahara, Takeshi, Bouet, Françoise, Laboute, Pierre, Letourneux, Yves, Ménez, André, Molgó, Jordi, Le Gall, Frédéric

“…A new specific voltage-sensitive calcium channel (VSCC) blocker has been isolated from the venom of the fish-hunting cone snail Conus consors. This peptide,…”
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Mechanisms of action of botulinum toxins and neurotoxins by Poulain, B, Lonchamp, E, Jover, E, Popoff, M R, Molgó, J

“…Several bacteria of the Clostridium genus (C. botulinum) produce 150 kDa di-chainal protein toxins referred as botulinum neurotoxins or BoNTs. They associate…”
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A reminder of the structure and function of the skeletal neuromuscular junction by Molgó, J, Colasante, C, Benoit, E, Poulain, B

“…The skeletal neuromuscular junction has been considered as a model of chemical synapses due to its relatively simple organization. It is made up of three…”
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The young open cluster NGC 7067 using Strömgren photometry by Monguió, M., Negueruela, I., Marco, A., González-Fernández, C., Alonso-Santiago, J., Costado, M. T., Casamiquela, L., López-Corredoira, M., Molgó, J., Vilardell, F., Alfaro, E. J., Antoja, T., Figueras, F., Garcia, M., Jordi, C., Romero-Gómez, M.

“…Abstract NGC 7067 is a young open cluster located in the direction between the first and the second Galactic quadrants and close to the Perseus spiral arm…”
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Ionic mechanisms implicated in ciguatoxin-induced membrane hyperexcitability and cell swelling by Mattei, C., Molgó, J., Benoit, E.

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Functional Repair of Motor Endplates after Botulinum Neurotoxin Type A Poisoning: Biphasic Switch of Synaptic Activity between Nerve Sprouts and their Parent Terminals by de Paiva, Anton, Meunier, Frédéric A., Molgó, Jordi, Aoki, K. Roger, Dolly, J. Oliver

“…Blockade of acetylcholine release by botulinum neurotoxin type A at the neuromuscular junction induces the formation of an extensive network of nerve-terminal…”
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Hyperosmolar d-mannitol reverses the increased membrane excitability and the nodal swelling caused by Caribbean ciguatoxin-1 in single frog myelinated axons by Mattei, César, Molgó, Jordi, Marquais, Michel, Vernoux, Jean-Paul, Benoit, Evelyne

“…The effects of hyperosmolar d-mannitol were studied on single frog myelinated nerve fibres previously poisoned with Caribbean ciguatoxin-1 (C-CTX-1), a new…”
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Recycling and refilling of transmitter quanta at the frog neuromuscular junction by Kloot, William, Cesare Colasante, Cameron, Roger, Molgó, Jordi

“…Fluorescent dyes have been used at the frog neuromuscular junction to label synaptic vesicular membrane. Retrieved membrane is reformed into vesicles, which…”
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Parallel activation of Ca²⁺-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress by Chiong, M, Parra, V, Eisner, V, Ibarra, C, Maldonado, C, Criollo, A, Bravo, R, Quiroga, C, Contreras, A, Vicencio, J. M, Cea, P, Bucarey, J. L, Molgó, J, Jaimovich, E, Hidalgo, C, Kroemer, G, Lavandero, S

“…Hyperosmotic stress promotes rapid and pronounced apoptosis in cultured cardiomyocytes. Here, we investigated if Ca²⁺ signals contribute to this response…”
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A new conotoxin isolated from Conus consors venom acting selectively on axons and motor nerve terminals through a Na+-dependent mechanism by Le Gall, Frédéric, Favreau, Philippe, Benoit, Evelyne, Mattei, César, Bouet, Françoise, Menou, Jean-Louis, Ménez, André, Letourneux, Yves, Molgó, Jordi

“…A novel conotoxin was isolated and characterized from the venom of the fish‐hunting marine snail Conus consors. The peptide was identified by screening…”
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Trachynilysin mediates SNARE-dependent release of catecholamines from chromaffin cells via external and stored Ca2 by Meunier, F A, Mattei, C, Chameau, P, Lawrence, G, Colasante, C, Kreger, A S, Dolly, J O, Molgó, J

“…Trachynilysin, a 159 kDa dimeric protein purified from stonefish (Synanceia trachynis) venom, dramatically increases spontaneous quantal transmitter release at…”
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A mouse model for congenital myasthenic syndrome due to MuSK mutations reveals defects in structure and function of neuromuscular junctions by Chevessier, Frédéric, Girard, Emmanuelle, Molgó, Jordi, Bartling, Sönke, Koenig, Jeanine, Hantaï, Daniel, Witzemann, Veit

“…In the muscle-specific tyrosine kinase receptor gene MUSK, a heteroallelic missense and a null mutation were identified in a patient suffering from a…”
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The strategy used by some piscivorous cone snails to capture their prey: the effects of their venoms on vertebrates and on isolated neuromuscular preparations by Le Gall, Frédéric, Favreau, Philippe, Richard, Georges, Yves Letourneux, Molgó, Jordi

“…Three piscivorous Conus species, C. ermineus, C. consor and C. catus were acclimatized in aquaria. The study of their strategy to capture the prey and details…”
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