Biological activities of the extracts from the Andaman Sea sponges, Thailand

Thirty six organic extracts were prepared from eighteen marine sponges collected from theAndaman Sea, Thailand. The extracts were examined for anti-malaria, anti-Microbacteriumtuberculosis, anti-herpes simplex virus, antimicrobial, anti-acetylcholinesterase enzyme andcytotoxic activities. Four extra...

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Bibliographic Details
Published in:	Eurasian journal of biosciences Vol. 2010; no. 4; pp. 63 - 69
Main Authors:	Pedpradab, Patchara, Molex, Wanlapa, Nukoolkarn, Veena, Darumas, Udomsak
Format:	Journal Article
Language:	English
Published:	EurAsian Journal of BioSciences 2010
Subjects:	Coğrafya İzmir Türkiye antimicrobial anti-malaria biological activity Andaman Sea marine sponges
Online Access:	Get full text
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Summary:	Thirty six organic extracts were prepared from eighteen marine sponges collected from theAndaman Sea, Thailand. The extracts were examined for anti-malaria, anti-Microbacteriumtuberculosis, anti-herpes simplex virus, antimicrobial, anti-acetylcholinesterase enzyme andcytotoxic activities. Four extracts showed anti-M. tuberculosis, one anti-malarial, twenty fourantimicrobial and one extract exhibited cytotoxic activity. However, anti-acetylcholinesteraseenzyme and anti-herpes simplex virus type 1 (HSV-1) activities were not recorded.Dichloromethane extracts prepared from Axinyssa sp., Halichondria sp. and Chondrosiareticulata exhibited potential anti-M. tuberculosis at MIC 50, 100 and 200 mg/mL,respectively. The Hexane part of Phakellia ventilabrum extract showed anti-malarial activity(MIC= 2.8 mg/mL) while the dichloromethane extract showed anti-M. tuberculosis andcytotoxic activity with MIC 200 and IC50 7.1 mg/mL, respectively. Antimicrobial activity wasfound in both the hexane and dichloromethane parts of extracts.
Bibliography:	TTAR
ISSN:	1307-9867 1307-9867
DOI:	10.5053/ejobios.2010.4.0.8