Search Results - "Molema, G."

Measurement of functional and morphodynamic neutrophil phenotypes in systemic inflammation and sepsis by Zonneveld, Rens, Molema, G, Plötz, Frans B

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Hypoxia-inducible factor-1 as regulator of angiogenesis in rheumatoid arthritis - therapeutic implications by Westra, Johanna, Molema, Grietje, Kallenberg, C G M

“…Angiogenesis plays an important role in the pathogenesis of inflammatory diseases, including rheumatoid arthritis (RA). The site and extent of inflammation and…”
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MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation by Asgeirsdóttir, S A, van Solingen, C, Kurniati, N F, Zwiers, P J, Heeringa, P, van Meurs, M, Satchell, S C, Saleem, M A, Mathieson, P W, Banas, B, Kamps, J A A M, Rabelink, T J, van Zonneveld, A J, Molema, G

“…Endothelial cells in different microvascular segments of the kidney have diverse functions and exhibit differential responsiveness to disease stimuli. The…”
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Antiviral activities of lactoferrin by van der Strate, B.W.A, Beljaars, L, Molema, G, Harmsen, M.C, Meijer, D.K.F

“…Lactoferrin (LF) is an iron binding glycoprotein that is present in several mucosal secretions. Many biological functions have been ascribed to LF. One of the…”
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In vivo characteristics of cationic liposomes as delivery vectors for gene therapy by AUDOUY, Sandrine A. L, DE LEIJ, Lou F. M. H, HOEKSTRA, Dick, MOLEMA, Grietje

“…After a decade of clinical trials, gene therapy seems to have found its place between excessive ambitions and feasible aims, with encouraging results obtained…”
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Liposome‐encapsulated dexamethasone attenuates ventilator‐induced lung inflammation by Hegeman, MA, Cobelens, PM, Kamps, JAAM, Hennus, MP, Jansen, NJG, Schultz, MJ, van Vught, AJ, Molema, G, Heijnen, CJ

“…BACKGROUND AND PURPOSE Systemic glucocorticoid therapy may effectively attenuate lung inflammation but also induce severe side‐effects. Delivery of…”
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Higher expression levels of angiogenic molecules in adjacent liver parenchyma of colorectal liver metastases treated with bevacizumab in combination with chemotherapy by van der Wal, G.E, Gouw, A.S.H, Hospers, G.A, Havenga, K, Molema, G, de Jong, K.P

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Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo by van der Veen, Betty S, Chen, Min, Müller, Ralf, van Timmeren, Mirjan M, Petersen, Arjen H, Lee, Patrice A, Satchell, Simon C, Mathieson, Peter W, Saleem, Moin A, Stegeman, Coen A, Zwerina, Jochen, Molema, Grietje, Heeringa, Peter

“…To determine whether inhibition of p38 mitogen-activated protein kinase (p38MAPK) reduces the pathogenicity of anti-neutrophil cytoplasmic autoantibodies…”
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Local Medial Microenvironment Directs Phenotypic Modulation of Smooth Muscle Cells After Experimental Renal Transplantation by Boersema, M., Katta, K., Rienstra, H., Molema, G., Nguyen, T. Q., Goldschmeding, R., Navis, G., van den Born, J., Popa, E. R., Hillebrands, J. L.

“…Smooth muscle cells (SMCs) play a key role in the pathogenesis of occlusive vascular diseases, including transplant vasculopathy. Neointimal SMCs in…”
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Generating hypotheses by discovering implicit associations in the literature: a case report of a search for new potential therapeutic uses for thalidomide by Weeber, Marc, Vos, Rein, Klein, Henny, De Jong-Van Den Berg, Lolkje T W, Aronson, Alan R, Molema, Grietje

“…The availability of scientific bibliographies through online databases provides a rich source of information for scientists to support their research. However,…”
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Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo by Kułdo, J.M., Ásgeirsdóttir, S.A., Zwiers, P.J., Bellu, A.R., Rots, M.G., Schalk, J.A.C., Ogawara, K.I., Trautwein, C., Banas, B., Haisma, H.J., Molema, G., Kamps, J.A.A.M.

“…In chronic inflammatory diseases the endothelium expresses mediators responsible for harmful leukocyte infiltration. We investigated whether targeted delivery…”
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Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis by van der Veen, B.S, Petersen, A.H, Belperio, J.A, Satchell, S.C, Mathieson, P.W, Molema, G, Heeringa, P

“…Myeloperoxidase (MPO)-anti-neutrophil cytoplasmic autoantibody (ANCA)-associated necrotizing crescentic glomerulonephritis (NCGN) is characterized by abundant…”
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Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells by Sikkema, A. H., de Bont, E. S. J. M., Molema, G., Dimberg, A., Zwiers, P. J., Diks, S. H., Hoving, E. W., Kamps, W. A., Peppelenbosch, M. P., den Dunnen, W. F. A.

“…A. H. Sikkema, E. S. J. M. de Bont, G. Molema, A. Dimberg, P. J. Zwiers, S. H. Diks, E. W. Hoving, W. A. Kamps, M. P. Peppelenbosch and W. F. A. den Dunnen…”
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Peptide-targeted PEG-liposomes in anti-angiogenic therapy by Janssen, A.P.C.A, Schiffelers, R.M, ten Hagen, T.L.M, Koning, G.A, Schraa, A.J, Kok, R.J, Storm, G, Molema, G

“…Peptides with the RGD amino acid sequence show affinity for the alpha(v)beta(3) integrin, an integrin which is over-expressed on angiogenic endothelium and…”
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Donor brain death reduces survival after transplantation in rat livers preserved for 20 HR by VAN DER HOEVEN, J. A. B, LINDELL, S, VAN SCHILFGAARDE, R, MOLEMA, G, TER HORST, G. J, SOUTHARD, J. H, PLOEG, R. J

“…Eighty percent of donor organs come from donors who have suffered brain trauma (brain-dead donors). This unphysiological state alters the hemodynamic and…”
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Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo by Beljaars, Leonie, van der Strate, Barry W.A., Bakker, Hester I., Reker-Smit, Catharina, van Loenen-Weemaes, Anne-miek, Wiegmans, Frouwke C., Harmsen, Martin C., Molema, Grietje, Meijer, Dirk K.F.

“…Lactoferrin is an antimicrobial agent, that, amongst other viruses, inhibits cytomegalovirus (CMV). In this study, we addressed the mechanism(s) by which…”
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Selective Intracellular Delivery of Dexamethasone into Activated Endothelial Cells Using an E-Selectin-Directed Immunoconjugate by Everts, Maaike, Kok, Robbert J, Asgeirsdottir, Sigridur A, Melgert, Barbro N, Moolenaar, Tom J. M, Koning, Gerben A, van Luyn, Marja J. A, Meijer, Dirk K. F, Molema, Grietje

“…In chronic inflammatory diseases, the endothelium is an attractive target for pharmacological intervention because it plays an important role in leukocyte…”
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The effect of surgical wounding on tumour development by Hofer, S.O.P., Molema, G., Hermens, R.A.E.C., Wanebo, H.J., Reichner, J.S., Hoekstra, H.J.

“…For more than a century, a role for wound healing in the outgrowth of tumours has been implied based on observations in both experimental and clinical studies…”
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Dissemination of Rat Cytomegalovirus through Infected Granulocytes and Monocytes In Vitro and In Vivo by van der Strate, B W A, Hillebrands, J L, Lycklama à Nijeholt, S S, Beljaars, L, Bruggeman, C A, Van Luyn, M J A, Rozing, J, The, T H, Meijer, D K F, Molema, G, Harmsen, M C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeting of the VEGF-kinase inhibitor PTK787 to angiogenic vasculature using RGD-equipped albumin carrier molecules by Temming, K., Lacombe, M., Moorlag, H.E., Asgeirsdottir, S.A., Orfi, L., Kéri, G., Poelstra, K., Molema, G., Kok, R.J.

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