Search Results - "Molek, Peter"

Peptide phage display as a tool for drug discovery: targeting membrane receptors by Molek, Peter, Strukelj, Borut, Bratkovic, Tomaz

“…Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein…”
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Epitope Mapping of Mono- and Polyclonal Antibodies by Screening Phage-displayed Random Peptide Libraries by Molek, Peter, Bratkovič, Tomaž

“…Detailed knowledge of antigenic determinants is crucial when characterizing therapeutic and diagnostic antibodies, assessing vaccine effectiveness and…”
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Aggregation of Recombinant Monoclonal Antibodies and Its Role in Potential Immunogenicity by Ignjatovic, Janko, Svajger, Urban, Ravnikar, Matjaz, Molek, Peter, Zadravec, Darko, Paris, Alenka, Strukelj, Borut

“…Development of new recombinant biotechnology products has greatly expanded in the field of modern pharmacy and medicine. Since biological recombinant molecules…”
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Peptide modulators of alpha-glucosidase by Roskar, Irena, Molek, Peter, Vodnik, Miha, Stempelj, Mateja, Strukelj, Borut, Lunder, Mojca

“…Aims/Introduction Acute glucose fluctuations during the postprandial period pose great risk for cardiovascular complications and thus represent an important…”
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Development and Characterization of Peptide Ligands of Immunoglobulin G Fc Region by Kruljec, Nika, Molek, Peter, Hodnik, Vesna, Anderluh, Gregor, Bratkovič, Tomaž

“…Affinity chromatography based on bacterial immunoglobulin (Ig)-binding proteins represents the cornerstone of therapeutic antibody downstream processing…”
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Bacteriophages as Scaffolds for Bipartite Display: Designing Swiss Army Knives on a Nanoscale by Molek, Peter, Bratkovič, Tomaž

“…Bacteriophages have been exploited as cloning vectors and display vehicles for decades owing to their genetic and structural simplicity. In bipartite display…”
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Fluorescent labeling of major honeybee allergens Api m 1 and Api m 2 with quantum dots and the development of a multiplex basophil activation test by Koren, Ana, Lunder, Mojca, Molek, Peter, Kopač, Peter, Zahirović, Abida, Gattinger, Pia, Mittermann, Irene, Valenta, Rudolf, Korošec, Peter

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Ligand Selection for Affinity Chromatography Using Phage Display by Bozovičar, Krištof, Molek, Peter, Bizjan, Barbara Jenko, Bratkovič, Tomaž

“…Phage display coupled with in vitro affinity selection to mimic evolutionary principles has propelled the discovery of specific binding peptides and proteins…”
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Kinetic mechanism of Enterococcus faeciumd-aspartate ligase by Škedelj, Veronika, Fonović, Urša Pečar, Molek, Peter, Magnet, Sophie, Mainardi, Jean-Luc, Blanot, Didier, Gobec, Stanislav, Stojan, Jure, Zega, Anamarija

“…Enterococcus faeciumd-aspartate ligase (Aslfm) is a peptide bond-forming enzyme that is involved in the peptidoglycan assembly pathway. It catalyzes the…”
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Bee Venom Immunotherapy: Current Status and Future Directions by Zahirović, Abida, Luzar, Jernej, Molek, Peter, Kruljec, Nika, Lunder, Mojca

“…Bee venom immunotherapy is the main treatment option for bee sting allergy. Its major limitations are the high percentage of allergic side effects and long…”
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Kinetic mechanism of Enterococcus faecium d-aspartate ligase by Škedelj, Veronika, Fonović, Urša Pečar, Molek, Peter, Magnet, Sophie, Mainardi, Jean-Luc, Blanot, Didier, Gobec, Stanislav, Stojan, Jure, Zega, Anamarija

“…Enterococcus faecium D-aspartate ligase (Aslfm) is a peptide bond-forming enzyme that is involved in the peptidoglycan assembly pathway. It catalyzes the…”
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Screening of synthetic phage display scFv libraries yields competitive ligands of human leptin receptor by Molek, Peter, Vodnik, Miha, Štrukelj, Borut, Bratkovič, Tomaž

“…•scFvs targeting human leptin receptor were isolated from phage display libraries.•Four unique scFvs competed with leptin for binding leptin receptor.•All…”
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Second-generation 4,5,6,7-tetrahydrobenzo[ d ]thiazoles as novel DNA gyrase inhibitors by Lamut, Andraž, Skok, Žiga, Barančoková, Michaela, Gutierrez, Lucas J, Cruz, Cristina D, Tammela, Päivi, Draskovits, Gábor, Szili, Petra Éva, Nyerges, Ákos, Pál, Csaba, Molek, Peter, Bratkovič, Tomaž, Ilaš, Janez, Zidar, Nace, Zega, Anamarija, Enriz, Ricardo D, Kikelj, Danijel, Tomašič, Tihomir

“…DNA gyrase and topoisomerase IV are essential bacterial enzymes, and in the fight against bacterial resistance, they are important targets for the development…”
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Identification and characterization of major cat allergen Fel d 1 mimotopes on filamentous phage carriers by Luzar, Jernej, Molek, Peter, Šilar, Mira, Korošec, Peter, Košnik, Mitja, Štrukelj, Borut, Lunder, Mojca

“…•Peptide mimotopes of cat allergen Fel d 1 were identified through immunoscreening.•Phage carriers with multiple copies of an individual mimotope were…”
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