Search Results - "Molecular imaging and biology"

Initial Evaluation of [18F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer by Szabo, Zsolt, Mena, Esther, Rowe, Steven P., Plyku, Donika, Nidal, Rosa, Eisenberger, Mario A., Antonarakis, Emmanuel S., Fan, Hong, Dannals, Robert F., Chen, Ying, Mease, Ronnie C., Vranesic, Melin, Bhatnagar, Akrita, Sgouros, George, Cho, Steve Y., Pomper, Martin G.

“…Purpose Prostate-specific membrane antigen (PSMA) is a recognized target for imaging prostate cancer. Here we present initial safety, biodistribution, and…”
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Repeatability of Radiomic Features in Non-Small-Cell Lung Cancer [18F]FDG-PET/CT Studies: Impact of Reconstruction and Delineation by van Velden, Floris H. P., Kramer, Gerbrand M., Frings, Virginie, Nissen, Ida A., Mulder, Emma R., de Langen, Adrianus J., Hoekstra, Otto S., Smit, Egbert F., Boellaard, Ronald

“…Purpose To assess (1) the repeatability and (2) the impact of reconstruction methods and delineation on the repeatability of 105 radiomic features in…”
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Comparison of [18F]DCFPyL and [68Ga]Ga-PSMA-HBED-CC for PSMA-PET Imaging in Patients with Relapsed Prostate Cancer by Dietlein, Markus, Kobe, Carsten, Kuhnert, Georg, Stockter, Simone, Fischer, Thomas, Schomäcker, Klaus, Schmidt, Matthias, Dietlein, Felix, Zlatopolskiy, Boris D., Krapf, Philipp, Richarz, Raphael, Neubauer, Stephan, Drzezga, Alexander, Neumaier, Bernd

“…Purpose Gallium-68 (Ga-68)-labeled tracers for imaging expression of the prostate-specific membrane antigen (PSMA) such as the [ 68 Ga]Ga-PSMA-HBED-CC have…”
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Next-Generation Radiogenomics Sequencing for Prediction of EGFR and KRAS Mutation Status in NSCLC Patients Using Multimodal Imaging and Machine Learning Algorithms by Shiri, Isaac, Maleki, Hasan, Hajianfar, Ghasem, Abdollahi, Hamid, Ashrafinia, Saeed, Hatt, Mathieu, Zaidi, Habib, Oveisi, Mehrdad, Rahmim, Arman

“…Purpose Considerable progress has been made in the assessment and management of non-small cell lung cancer (NSCLC) patients based on mutation status in the…”
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Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues by Porta Siegel, Tiffany, Hamm, Gregory, Bunch, Josephine, Cappell, Jo, Fletcher, John S., Schwamborn, Kristina

“…Over the last two decades, mass spectrometry imaging (MSI) has been increasingly employed to investigate the spatial distribution of a wide variety of…”
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PSMA-Based [18F]DCFPyL PET/CT Is Superior to Conventional Imaging for Lesion Detection in Patients with Metastatic Prostate Cancer by Rowe, Steven P., Macura, Katarzyna J., Mena, Esther, Blackford, Amanda L., Nadal, Rosa, Antonarakis, Emmanuel S., Eisenberger, Mario, Carducci, Michael, Fan, Hong, Dannals, Robert F., Chen, Ying, Mease, Ronnie C., Szabo, Zsolt, Pomper, Martin G., Cho, Steve Y.

“…Purpose Current standard of care conventional imaging modalities (CIM) such as X-ray computed tomography (CT) and bone scan can be limited for detection of…”
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Recent Trends in Diagnostic Biomarkers of Tumor Microenvironment by Siminzar, Paniz, Tohidkia, Mohammad Reza, Eppard, Elisabeth, Vahidfar, Nasim, Tarighatnia, Ali, Aghanejad, Ayuob

“…The tumor microenvironment (TME) play critical roles in tumor survival, progression, and metastasis and can be considered potential targets for molecular…”
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The Evolving Role of FDG-PET/CT in the Diagnosis, Staging, and Treatment of Breast Cancer by Paydary, Koosha, Seraj, Siavash Mehdizadeh, Zadeh, Mahdi Zirakchian, Emamzadehfard, Sahra, Shamchi, Sara Pourhassan, Gholami, Saeid, Werner, Thomas J., Alavi, Abass

“…The applications of 2-deoxy-2-[ 18 F]fluoro- d -glucose positron emission tomography/X-ray computed tomography (PET/CT) in the management of patients with…”
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Magnetic Resonance Imaging of Hard Tissues and Hard Tissue Engineered Bio-substitutes by Mastrogiacomo, Simone, Dou, Weiqiang, Jansen, John A., Walboomers, X. Frank

“…Magnetic resonance imaging (MRI) is a non-invasive diagnostic imaging tool based on the detection of protons into the tissues. This imaging technique is…”
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Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages by Xavier, Catarina, Blykers, Anneleen, Laoui, Damya, Bolli, Evangelia, Vaneyken, Ilse, Bridoux, Jessica, Baudhuin, Henri, Raes, Geert, Everaert, Hendrik, Movahedi, Kiavash, Van Ginderachter, Jo A., Devoogdt, Nick, Caveliers, Vicky, Lahoutte, Tony, Keyaerts, Marleen

“…Purpose Macrophage mannose receptor (MMR, CD206) expressing tumor-associated macrophages (TAM) are protumorigenic and was reported to negatively impact therapy…”
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Radiomics Analysis of PET and CT Components of PET/CT Imaging Integrated with Clinical Parameters: Application to Prognosis for Nasopharyngeal Carcinoma by Lv, Wenbing, Yuan, Qingyu, Wang, Quanshi, Ma, Jianhua, Feng, Qianjin, Chen, Wufan, Rahmim, Arman, Lu, Lijun

“…Purpose To investigate the prognostic performance of radiomics features, as extracted from positron emission tomography (PET) and X-ray computed tomography…”
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Radiomic Signatures Derived from Diffusion-Weighted Imaging for the Assessment of Breast Cancer Receptor Status and Molecular Subtypes by Leithner, Doris, Bernard-Davila, Blanca, Martinez, Danny F., Horvat, Joao V., Jochelson, Maxine S., Marino, Maria Adele, Avendano, Daly, Ochoa-Albiztegui, R. Elena, Sutton, Elizabeth J., Morris, Elizabeth A., Thakur, Sunitha B., Pinker, Katja

“…Purpose To compare annotation segmentation approaches and to assess the value of radiomics analysis applied to diffusion-weighted imaging (DWI) for evaluation…”
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Development of Novel ImmunoPET Tracers to Image Human PD-1 Checkpoint Expression on Tumor-Infiltrating Lymphocytes in a Humanized Mouse Model by Natarajan, Arutselvan, Mayer, Aaron T., Reeves, Robert E., Nagamine, Claude M., Gambhir, Sanjiv Sam

“…Purpose It is well known that cancers exploit immune checkpoints (programmed death 1 receptor (PD-1) and its ligand (PD-L1)) to evade anti-tumor immune…”
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SUV of [68Ga]DOTATOC-PET/CT Predicts Response Probability of PRRT in Neuroendocrine Tumors by Kratochwil, C., Stefanova, M., Mavriopoulou, E., Holland-Letz, T., Dimitrakopoulou-Strauss, A., Afshar-Oromieh, A., Mier, W., Haberkorn, U., Giesel, F. L.

“…Purpose The goal of our study was to quantify the expression of the somatostatin receptors (SSTR2) using the maximum standardized uptake value (SUVmax) of [ 68…”
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Subregional Radiomics Analysis of PET/CT Imaging with Intratumor Partitioning: Application to Prognosis for Nasopharyngeal Carcinoma by Xu, Hui, Lv, Wenbing, Feng, Hui, Du, Dongyang, Yuan, Qingyu, Wang, Quanshi, Dai, Zhenhui, Yang, Wei, Feng, Qianjin, Ma, Jianhua, Lu, Lijun

“…Purpose This work aims to identify intratumoral habitats with distinct heterogeneity based on 2-deoxy-2-[ 18 F]fluro- d -glucose positron emission tomography…”
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Machine Learning Methods for Optimal Radiomics-Based Differentiation Between Recurrence and Inflammation: Application to Nasopharyngeal Carcinoma Post-therapy PET/CT Images by Du, Dongyang, Feng, Hui, Lv, Wenbing, Ashrafinia, Saeed, Yuan, Qingyu, Wang, Quanshi, Yang, Wei, Feng, Qianjin, Chen, Wufan, Rahmim, Arman, Lu, Lijun

“…Purpose To identify optimal machine learning methods for radiomics-based differentiation of local recurrence versus inflammation from post-treatment…”
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Imaging Nanomedicine-Based Drug Delivery: a Review of Clinical Studies by Man, Francis, Lammers, Twan, T. M. de Rosales, Rafael

“…Imaging plays a key role in the preclinical evaluation of nanomedicine-based drug delivery systems and it has provided important insights into their mechanism…”
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The Evolution of Fluorescence-Guided Surgery by Van Keulen, Stan, Hom, Marisa, White, Haley, Rosenthal, Eben L., Baik, Fred M

“…There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA…”
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Integration of PET/CT Radiomics and Semantic Features for Differentiation between Active Pulmonary Tuberculosis and Lung Cancer by Du, Dongyang, Gu, Jiamei, Chen, Xiaohui, Lv, Wenbing, Feng, Qianjin, Rahmim, Arman, Wu, Hubing, Lu, Lijun

“…Purpose We aim to accurately differentiate between active pulmonary tuberculosis (TB) and lung cancer (LC) based on radiomics and semantic features as…”
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Contrast-Enhanced Mammography and Radiomics Analysis for Noninvasive Breast Cancer Characterization: Initial Results by Marino, Maria Adele, Pinker, Katja, Leithner, Doris, Sung, Janice, Avendano, Daly, Morris, Elizabeth A., Jochelson, Maxine

“…Purpose To investigate the potential of contrast-enhanced mammography (CEM) and radiomics analysis for the noninvasive differentiation of breast cancer…”
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