Search Results - "Moldow, C F"

Mechanism of tissue factor activation on HL-60 cells by BACH, R. R, MOLDOW, C. F

“…Tissue factor (TF) procoagulant activity (PCA) on the surface of intact HL-60 cells is encrypted. This latent TF PCA was activated by exposing the cells to…”
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Apoptosis is associated with increased cell surface tissue factor procoagulant activity by Greeno, E W, Bach, R R, Moldow, C F

“…Tissue factor (TF), the physiologic initiator of coagulation, is present on the surface of cells but is not fully active unless the cell is lysed. This…”
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Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium by GREENO, E. W, MANTYH, P, VERCELLOTTI, G. M, MOLDOW, C. F

“…Substance P (SP), a neurotachykinin, is important in a number of inflammatory processes in which the endothelial cell also plays a critical role. SP receptors…”
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Magnesium Sulfate: Rationale for Its Use in Preeclampsia by Watson, Kathleen V., Moldow, Charles F., Ogburn, Paul L., Jacob, Harry S.

“…Preeclampsia is a disorder of pregnancy characterized clinically by hypertension, proteinuria, and edema and characterized pathologically in its late stages by…”
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Infection of Vascular Endothelial Cells with Herpes Simplex Virus Enhances Tissue Factor Activity and Reduces Thrombomodulin Expression by Key, Nigel S., Vercellotti, Gregory M., Winkelmann, John C., Moldow, Charles F., Goodman, Jesse L., Esmon, Naomi L., Esmon, Charles T., Jacob, Harry S.

“…Latent infection of vascular cells with herpes-viruses may play a pathogenic role in the development of human atherosclerosis. In a previous study, we found…”
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Induction of endothelial tissue factor by endotoxin and its precursors by Moldow, C F, Bach, R R, Staskus, K, Rick, P D

“…The structural determinants of lipopolysaccharide required for the induction of tissue factor in human umbilical vein endothelial cells were studied. Intact…”
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Herpes simplex virus type I does not require productive infection to induce tissue factor in human umbilical vein endothelial cells by Key, N S, Bach, R R, Vercellotti, G M, Moldow, C F

“…Herpes simplex virus (HSV)-infected endothelium is a model for vascular injury and possibly the development of atherosclerosis. In vitro infection of human…”
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Endothelial cell heterogeneity: antioxidant profiles determine vulnerability to oxidant injury by Vercellotti, G M, Dobson, M, Schorer, A E, Moldow, C F

“…Human umbilical vein endothelial cells were more sensitive to hydrogen peroxide lysis than cow pulmonary artery endothelial cells. Conversely, activated…”
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Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage by Sacks, T, Moldow, C F, Craddock, P R, Bowers, T K, Jacob, H S

“…During hemodialysis, alternative pathway complement activation leads to pulmonary sequestration of granulocytes, with loss of pulmonary vascular endothelial…”
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Protection against Lethal Hyperoxia by Tracheal Insufflation of Erythrocytes: Role of Red Cell Glutathione by Van Asbeck, B. Sweder, Hoidal, John, Vercellotti, Gregory M., Schwartz, Bruce A., Moldow, Charles F., Jacob, Harry S.

“…Intact erythrocytes placed into the tracheobronchial tree of hyperoxic rats dramatically improved their chances for survival. Over 70 percent of the animals so…”
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Interleukin 1 stimulates endothelial cell tissue factor production and expression by a prostaglandin-independent mechanism by Schorer, A E, Kaplan, M E, Rao, G H, Moldow, C F

“…Activation of coagulation occurs at inflammatory sites following the ingress of mononuclear cells, and may result from alterations in the vessel wall. Since…”
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Enhancement of Granulocyte--Endothelial Cell Adherence and Granulocyte-Induced Cytotoxicity by Platelet Release Products by Boogaerts, Marc A., Yamada, Osamu, Jacob, Harry S., Moldow, Charles F.

“…Complement-stimulated granulocytes adhere to and induce significant51Cr release from endothelial cells in vitro. Platelets were stimulated to undergo release,…”
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Enkephalins modify granulocyte-endothelial interactions by stimulating prostacyclin production by Boogaerts, M A, Vermylen, J, Deckmyn, H, Roelant, C, Verwilghen, R L, Jacob, H S, Moldow, C F

“…Granulocyte (PMN)-endothelial interactions have been implicated in the primary events of vascular injury and atherogenesis. We now present data which show that…”
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Soluble CD14 promotes LPS activation of CD14-deficient PNH monocytes and endothelial cells by Golenbock, D T, Bach, R R, Lichenstein, H, Juan, T S, Tadavarthy, A, Moldow, C F

“…Bacterial lipopolysaccharide (LPS) initiates the cascade of inflammatory events that, in infected patients, often result in a lethal systemic inflammatory…”
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Hydrogen peroxide alters signal transduction in human endothelial cells by Vercellotti, G M, Severson, S P, Duane, P, Moldow, C F

“…Lytic H2O2-induced injury to human umbilical vein endothelial cells provides a model for endothelial cell damage in diverse states including acute respiratory…”
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Plasma exchange in the treatment of immune disease by Branda, R F, Moldow, C F, McCullough, J J, Jacob, H S

“…Plasma exchange was investigated as an alternative to the use of toxic drugs to remove unwanted antibody. Studies in rabbits immunized with bovine serum…”
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Measurement of intracellular calcium concentration in intact monolayers of human endothelial cells by Wickham, N W, Vercellotti, G M, Moldow, C F, Visser, M R, Jacob, H S

“…Intracellular calcium ([Ca++]i) plays an important role in signal transduction and cell activation. The measurement of [Ca++]i in intact monolayers of human…”
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Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease by Hebbel, R P, Yamada, O, Moldow, C F, Jacob, H S, White, J G, Eaton, J W

“…The abnormal shape and poor deformability of the sickled erythrocyte (RBC) have generally been held responsible for the microvascular occlusions of sickle cell…”
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Structural features of endotoxin required for stimulation of endothelial cell tissue factor production; exposure of preformed tissue factor after oxidant-mediated endothelial cell injury by Schorer, A E, Rick, P D, Swaim, W R, Moldow, C F

“…Cultured human umbilical vein endothelial cells synthesize the procoagulant, tissue factor, after exposure to bacterial endotoxin. Wild-type lipopolysaccharide…”
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Solubilization of initial attachment site activity for avian tumor viruses with lithium diiodosalicylate by Moldow, C F, McGrath, M, Peterson, C

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