Search Results - "Mold, David E."
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Regulation of Zebrafish Zona Pellucida Gene Activity in Developing Oocytes
Published in Biology of reproduction (01-07-2009)“…The two major zona pellucida proteins of the zebrafish chorion, Zp2 and Zp3, are encoded by multicopy genes arranged in tandem arrays on chromosomes 20 and 2,…”
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Systemic Treatment with Tetra-O-Methyl Nordihydroguaiaretic Acid Suppresses the Growth of Human Xenograft Tumors
Published in Clinical cancer research (15-06-2005)“…Purpose: We have previously shown that the transcriptional inhibitor tetra- O -methyl nordihydroguaiaretic acid (M 4 N) induces growth arrest in tumor cells…”
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3
In vivo amelioration of endogenous antitumor autoantibodies via low-dose P₄N through the LTA4H/activin A/BAFF pathway
Published in Proceedings of the National Academy of Sciences - PNAS (29-11-2016)“…Cancer progression is associated with the development of antitumor autoantibodies in patients’ sera. Although passive treatment with antitumor antibodies has…”
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Cluster of genes encoding the major egg envelope protein of zebrafish
Published in Molecular reproduction and development (01-01-2001)“…The proteins of fish egg envelopes are encoded by genes that are closely related to the genes for human zona pellucida proteins. A cluster of three genes…”
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Hepatocellular Carcinoma Targeting Agents: Conjugates of Nitroimidazoles with Trimethyl Nordihydroguaiaretic Acid
Published in ChemMedChem (01-05-2014)“…Cancer has been a primary global health issue for decades, with hepatocellular carcinoma (HCC) resulting in more than half a million new cases annually. With…”
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6
Regulation of Zebrafish Zona Pellucida Gene Activity in Developing Oocytes1
Published in Biology of reproduction (01-07-2009)“…The two major zona pellucida proteins of the zebrafish chorion, Zp2 and Zp3, are encoded by multicopy genes arranged in tandem arrays on chromosomes 20 and 2,…”
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Reversal of multidrug resistance by two nordihydroguaiaretic acid derivatives, M4N and maltose-M3N, and their use in combination with doxorubicin or paclitaxel
Published in Cancer chemotherapy and pharmacology (01-11-2006)“…Multidrug resistance (MDR) continues to be a major obstacle for successful anticancer therapy. One of the principal factors implicated in MDR is the over…”
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Inhibition of HSV-1 replication and reactivation by the mutation-insensitive transcription inhibitor tetra- O-glycyl-nordihydroguaiaretic acid
Published in Antiviral research (01-03-2003)“…Methylated derivatives of nordihydroguaiaretic acid (NDGA)were previously shown to be potent mutation-resistant inhibitors of herpes simplex virus type 1…”
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Antiviral Activities of Methylated Nordihydroguaiaretic Acids. 2. Targeting Herpes Simplex Virus Replication by the Mutation Insensitive Transcription Inhibitor Tetra-O-methyl-NDGA
Published in Journal of medicinal chemistry (30-07-1998)“…We had previously reported that tetramethyl-O-NGDA (M4N), a synthetic derivative of the naturally occurring nordihydroguaiaretic acid (NDGA), is able to…”
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10
In vivo amelioration of endogenous antitumor autoantibodies via low-dose P 4 N through the LTA4H/activin A/BAFF pathway
Published in Proceedings of the National Academy of Sciences - PNAS (29-11-2016)“…This study finds that a small-molecule drug (P 4 N) is able to inhibit tumor growth by augmentation of endogenous antitumor autoantibodies (EAAs). We show that…”
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The Mouse Intracisternal A Particle-Promoted Placental Gene Retrotransposition is Mouse-Strain-Specific
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1993)“…Insertion of a single long terminal repeat (LTR) of an intracisternal A particle (IAP) gene into a placenta-expressed cellular gene (mouse IAP-promoted…”
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A Chinese hamster ovary cell histone deacetylase that is associated with a unique class of mononucleosomes
Published in Biochemistry (Easton) (15-12-1987)“…The chromatin-bound histone deacetylase of Chinese hamster ovary cells has been studied by using as a substrate an acetylated amino-terminal peptide of histone…”
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Identification of a novel murine IAP-promoted placenta-expressed gene
Published in Nucleic acids research (11-07-1991)“…We have cloned and characterized a novel cellular gene that is promoted by an intracisternal A-particle (IAP) LTR and expressed in the mouse placenta (mouse…”
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Cell lineage-specific expression of the MIPP gene
Published in Biochemical and biophysical research communications (28-06-1991)“…The expression of the mouse IAP promoted placental (MIPP) gene was examined in the tissues of the 13.5 day mouse conceptus by Northern hybridization analysis…”
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Silver staining of histones in Triton-acid-urea gels
Published in Analytical biochemistry (01-11-1983)“…A reliable method for silver staining histones in Triton-acid-urea gels was developed. Optimum staining is achieved by treating the gels either with amido…”
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