Search Results - "Mokuda, Sho"

Wwp2 maintains cartilage homeostasis through regulation of Adamts5 by Mokuda, Sho, Nakamichi, Ryo, Matsuzaki, Tokio, Ito, Yoshiaki, Sato, Tempei, Miyata, Kohei, Inui, Masafumi, Olmer, Merissa, Sugiyama, Eiji, Lotz, Martin, Asahara, Hiroshi

“…The WW domain-containing protein 2 ( Wwp2 ) gene, the host gene of miR-140, codes for the Wwp2 protein, which is an HECT-type E3 ubiquitin ligases abundantly…”
Get full text

Angiotensin-converting Enzyme 2, a SARS-CoV-2 Receptor, Is Upregulated by Interleukin 6 through STAT3 Signaling in Synovial Tissues by Mokuda, Sho, Tokunaga, Tadahiro, Masumoto, Junya, Sugiyama, Eiji

Get full text

FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis by Matsuzaki, Tokio, Alvarez-Garcia, Oscar, Mokuda, Sho, Nagira, Keita, Olmer, Merissa, Gamini, Ramya, Miyata, Kohei, Akasaki, Yukio, Su, Andrew I, Asahara, Hiroshi, Lotz, Martin K

“…Aging is a main risk factor for osteoarthritis (OA). FoxO transcription factors protect against cellular and organismal aging, and FoxO expression in cartilage…”
Get more information

Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis by Ito, Yoshiaki, Matsuzaki, Tokio, Ayabe, Fumiaki, Mokuda, Sho, Kurimoto, Ryota, Matsushima, Takahide, Tabata, Yusuke, Inotsume, Maiko, Tsutsumi, Hiroki, Liu, Lin, Shinohara, Masahiro, Tanaka, Yoko, Nakamichi, Ryo, Nishida, Keiichiro, Lotz, Martin K., Asahara, Hiroshi

“…Osteoarthritis (OA), the most common aging-related joint disease, is caused by an imbalance between extracellular matrix synthesis and degradation. Here, we…”
Get full text

Dissecting the roles of miR-140 and its host gene by Inui, Masafumi, Mokuda, Sho, Sato, Tempei, Tamano, Moe, Takada, Shuji, Asahara, Hiroshi

Get full text

Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s by Kong, Weng Sheng, Tsuyama, Naohiro, Inoue, Hiroko, Guo, Yun, Mokuda, Sho, Nobukiyo, Asako, Nakatani, Nobuhiro, Yamaide, Fumiya, Nakano, Taiji, Kohno, Yoichi, Ikeda, Kazutaka, Nakanishi, Yumiko, Ohno, Hiroshi, Arita, Makoto, Shimojo, Naoki, Kanno, Masamoto

“…Breastfeeding influences the immune system development in infants and may even affect various immunological responses later in life. Breast milk provides a…”
Get full text

Safe Introduction of Hydroxychloroquine Focusing on Early Intolerance Due to Adverse Drug Reactions in Patients with Systemic Lupus Erythematosus by Yoshida, Yusuke, Oka, Naoya, Yorishima, Ai, Masuda, Sho, Ishitoku, Michinori, Araki, Kei, Kohno, Hiroki, Watanabe, Hirofumi, Sugimoto, Tomohiro, Mokuda, Sho, Hirata, Shintaro

“…Objective This study explored the predictors of hydroxychloroquine intolerance and propose appropriate methods to initiate hydroxychloroquine in patients with…”
Get full text

Cryoglobulinemic Vasculitis Associated with Monoclonal Gammopathy of Undetermined Significance Developed after Sustained Virologic Response of Hepatitis C by Ishitoku, Michinori, Yoshida, Yusuke, Matsubara, Toshiki, Fujii, Kenji, Yorishima, Ai, Oka, Naoya, Masuda, Sho, Sugimoto, Tomohiro, Mokuda, Sho, Masaki, Takao, Hirata, Shintaro

“…A 72-year-old woman had a history of chronic hepatitis C virus (HCV) infection previously treated with interferon to achieve a sustained virologic response…”
Get full text

Comment on: Nailfold capillaries and myositis-specific antibodies in anti-melanoma differentiation-associated gene 5 antibody-positive DM. Reply by Sugimoto, Tomohiro, Mokuda, Sho, Kohno, Hiroki, Ishitoku, Michinori, Araki, Kei, Watanabe, Hirofumi, Tokunaga, Tadahiro, Yoshida, Yusuke, Hirata, Shintaro, Sugiyama, Eiji

Get full text

The Efficacy of Amenamevir for the Treatment of Disseminated Herpes Zoster Complicated with Probable Varicella-zoster Pneumonia in an Immunocompromised Patient by Kobayashi, Hiroki, Yoshida, Yusuke, Komoshita, Tomoki, Suma, Harumichi, Hosokawa, Yohei, Hirose, Yoshikazu, Sugimoto, Tomohiro, Mokuda, Sho, Hirata, Shintaro, Sugiyama, Eiji

“…We herein report the case of a 78-year-old woman who was diagnosed as having disseminated herpes zoster (DHZ) complicated with probable varicella-zoster…”
Get full text

Nailfold capillaries and myositis-specific antibodies in anti–melanoma differentiation–associated gene 5 antibody-positive dermatomyositis by Sugimoto, Tomohiro, Mokuda, Sho, Kohno, Hiroki, Ishitoku, Michinori, Araki, Kei, Watanabe, Hirofumi, Tokunaga, Tadahiro, Yoshida, Yusuke, Hirata, Shintaro, Sugiyama, Eiji

“…Abstract Objectives This study aimed to quantify nailfold capillary (NFC) abnormalities in anti–melanoma differentiation–associated gene 5 (MDA5) -positive DM…”
Get full text

N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes by Mokuda, Sho, Watanabe, Hirofumi, Kohno, Hiroki, Ishitoku, Michinori, Araki, Kei, Hirata, Shintaro, Sugiyama, Eiji

“…Studies conducted using murine arthritis models have indicated that the use of in vitro-transcribed messenger RNA (IVT mRNA) is an effective therapeutic…”
Get full text

TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression by Tokunaga, Tadahiro, Mokuda, Sho, Kohno, Hiroki, Yukawa, Kazutoshi, Kuranobu, Tatsuomi, Oi, Katsuhiro, Yoshida, Yusuke, Hirata, Shintaro, Sugiyama, Eiji

“…Osteoclasts are multinucleated giant cells responsible for bone resorption. Various mediators involved in osteoclast differentiation have been investigated as…”
Get full text

The prevalence of endoscopic gastric mucosal damage in patients with rheumatoid arthritis by Tsujimoto, Saki, Mokuda, Sho, Matoba, Kenichiro, Yamada, Akihiro, Jouyama, Kazuo, Murata, Yosuke, Ozaki, Yoshio, Ito, Tomoki, Nomura, Shosaku, Okuda, Yasuaki

“…Rheumatoid arthritis (RA) patients often take non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids as supportive drugs. In this study, we…”
Get full text

Comment on: Combination of immunosuppressive therapy and nintedanib improves capillaroscopic changes in systemic sclerosis–interstitial lung disease: a case report by Sugimoto, Tomohiro, Yoshida, Yusuke, Mokuda, Sho, Hirata, Shintaro

Get full text

Lower CH50 as a predictor for intractable or recurrent lupus enteritis: A retrospective observational study by Yoshida, Yusuke, Omoto, Takuji, Kohno, Hiroki, Tokunaga, Tadahiro, Kuranobu, Tatsuomi, Yukawa, Kazutoshi, Watanabe, Hirofumi, Oi, Katsuhiro, Sugimoto, Tomohiro, Mokuda, Sho, Nojima, Takaki, Hirata, Shintaro, Sugiyama, Eiji

“…Lupus enteritis (LE) is a rare but well-known gastrointestinal manifestation of systemic lupus erythematosus (SLE). This study was conducted to identify…”
Get full text

Tumor Necrosis Factor and Interleukin-1β Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation by Ishitoku, Michinori, Mokuda, Sho, Araki, Kei, Watanabe, Hirofumi, Kohno, Hiroki, Sugimoto, Tomohiro, Yoshida, Yusuke, Sakaguchi, Takemasa, Masumoto, Junya, Hirata, Shintaro, Sugiyama, Eiji

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), utilizes the host receptor…”
Get full text

Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling by Watanabe, Hirofumi, Mokuda, Sho, Tokunaga, Tadahiro, Kohno, Hiroki, Ishitoku, Michinori, Araki, Kei, Sugimoto, Tomohiro, Yoshida, Yusuke, Yamamoto, Toshihiro, Matsumoto, Mayuko, Masumoto, Junya, Hirata, Shintaro, Sugiyama, Eiji

“…Blood coagulation factor XIII (FXIII) promotes cross-linking between fibrin molecules at the final stage of the blood coagulation cascade. However, its…”
Get full text

Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases by Okuda, Yasuaki, Ohnishi, Makoto, Matoba, Kenichiro, Jouyama, Kazuo, Yamada, Akihiro, Sawada, Naoya, Mokuda, Sho, Murata, Yousuke, Takasugi, Kiyoshi

“…Abstract Objectives Anti-cytokine therapy is reportedly useful in amyloid A (AA) amyloidosis complicating rheumatic diseases. However, to date no studies have…”
Get full text

Tapering and discontinuation of oral glucocorticoids without deterioration of disease status in patients with rheumatoid arthritis under a stable treatment by Hirata, Shintaro, Kohno, Hiroki, Watanabe, Hirofumi, Tokunaga, Tadahiro, Yoshida, Yusuke, Sugimoto, Tomohiro, Mokuda, Sho, Oda, Keisuke, Nojima, Takaki, Sugiyama, Eiji

“…To retrospectively evaluate whether oral glucocorticoid (GC) administration can be tapered or discontinued over a 2-year observation period in patients with…”
Get full text