Search Results - "Mokry Juraj"

Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis by Mokra, Daniela, Joskova, Marta, Mokry, Juraj

“…(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea. Thanks to multiple interactions with cell surface receptors, intracellular…”
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Corticosteroids in Acute Lung Injury: The Dilemma Continues by Mokra, Daniela, Mikolka, Pavol, Kosutova, Petra, Mokry, Juraj

“…Acute lung injury (ALI) represents a serious heterogenous pulmonary disorder with high mortality. Despite improved understanding of the pathophysiology, the…”
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Phosphodiesterase Inhibitors in Acute Lung Injury: What Are the Perspectives? by Mokra, Daniela, Mokry, Juraj

“…Despite progress in understanding the pathophysiology of acute lung damage, currently approved treatment possibilities are limited to lung-protective…”
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Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG): A Time for a New Player in the Treatment of Respiratory Diseases? by Mokra, Daniela, Adamcakova, Jana, Mokry, Juraj

“…(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a wide variety of actions. EGCG acts as a strong antioxidant which…”
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Advancing tuberculosis management: the role of predictive, preventive, and personalized medicine by Dohál, Matúš, Porvazník, Igor, Solovič, Ivan, Mokrý, Juraj

“…Tuberculosis is a major global health issue, with approximately 10 million people falling ill and 1.4 million dying yearly. One of the most significant…”
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Whole genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates collected in the Czech Republic, 2005–2020 by Dohál, Matúš, Dvořáková, Věra, Šperková, Miluše, Pinková, Martina, Spitaleri, Andrea, Norman, Anders, Cabibbe, Andrea Maurizio, Rasmussen, Erik Michael, Porvazník, Igor, Škereňová, Mária, Solovič, Ivan, Cirillo, Daniela Maria, Mokrý, Juraj

“…The emergence and spread of resistant tuberculosis (TB) pose a threat to public health, so it is necessary to diagnose the drug-resistant forms in a clinically…”
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Exploring cytokine dynamics in tuberculosis: A comparative analysis of patients and controls with insights from three-week antituberculosis intervention by Krivosová, Michaela, Dohál, Matús, Mäsiarová, Simona, Prso, Kristián, Gondás, Eduard, Murín, Radovan, Franová, Sona, Porvazník, Igor, Solovic, Ivan, Mokrý, Juraj

“…Despite developing new diagnostics, drugs, and vaccines, treating tuberculosis (TB) remains challenging. Monitoring inflammatory markers can contribute to more…”
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Association of Sleep Architecture and Physiology with Depressive Disorder and Antidepressants Treatment by Hutka, Peter, Krivosova, Michaela, Muchova, Zuzana, Tonhajzerova, Ingrid, Hamrakova, Andrea, Mlyncekova, Zuzana, Mokry, Juraj, Ondrejka, Igor

“…Sleep problems are frequently associated with the principal diagnostic criteria for many mental disorders. Alterations in the sleep of depressive patients are…”
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Epidemiology of non-tuberculous mycobacterial diseases in Slovakia during the years 2016–2021 by Dohál, Matúš, Porvazník, Igor, Krivošová, Michaela, Solovič, Ivan, Mokrý, Juraj

“…Nontuberculous mycobacteria (NTM) are opportunistic human pathogens found worldwide, primarily in the environment. They predominantly affect the lungs,…”
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A high‐throughput LC–MS/MS method for simultaneous determination of isoniazid, ethambutol and pyrazinamide in human plasma by Pršo, Kristián, Žideková, Nela, Porvazník, Igor, Solovič, Ivan, Mokrý, Juraj, Kertys, Martin

“…Rationale Tuberculosis (TB) remains a challenging global infectious disease, mainly affecting the lungs. First‐line anti‐TB drugs play a crucial role in…”
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Inhibitors of phosphodiesterases in the treatment of cough by Mokry, Juraj, Urbanova, Anna, Kertys, Martin, Mokra, Daniela

“…•Xanthine derivatives inhibit PDEs non-selectively leading to bronchodilation, anti-inflammatory, and antitussive effects.•The inhibition of PDEs leads to…”
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Respiratory Cilia as a Therapeutic Target of Phosphodiesterase Inhibitors by Joskova, Marta, Mokry, Juraj, Franova, Sona

“…Mucociliary clearance is an essential airway defense mechanism dependent predominantly on the proper ciliary function and mucus rheology. The crucial role of…”
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Whole-genome sequencing and Mycobacterium tuberculosis: Challenges in sample preparation and sequencing data analysis by Dohál, Matúš, Porvazník, Igor, Pršo, Kristián, Rasmussen, Erik Michael, Solovič, Ivan, Mokrý, Juraj

“…The numbers of patients with tuberculosis (TB) caused by resistant strains are still alarming. Therefore, it is necessary to determine resistance more quickly…”
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Whole Genome Sequencing in the Management of Non-Tuberculous Mycobacterial Infections by Dohál, Matúš, Porvazník, Igor, Solovič, Ivan, Mokrý, Juraj

“…Infections caused by non-tuberculous mycobacteria (NTM) have been a public health problem in recent decades and contribute significantly to the clinical and…”
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Simultaneous determination of caffeine and its metabolites in rat plasma by UHPLC‐MS/MS by Kertys, Martin, Žideková, Nela, Pršo, Kristián, Maráková, Katarína, Kmeťová, Katarína, Mokrý, Juraj

“…Caffeine is a widely consumed psychostimulant with several mechanisms of action and various positive and negative effects on organisms. Caffeine undergoes…”
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Sex-Based Differences in Bronchial Asthma: What Are the Mechanisms behind Them? by Mokra, Daniela, Barosova, Romana, Mokry, Juraj

“…Sex-based differences in bronchial asthma can already be observed in childhood, at which time allergic atopic asthma is more frequently found in boys than in…”
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Editorial: Phosphodiesterases as Drug Targets in Airway and Inflammatory Diseases by Mokry, Juraj, Giembycz, Mark, Mokra, Daniela

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Vortioxetine’s impact on the autonomic nervous system in depressed children and adolescents: analysis of the heart rate variability by Krivosova, Michaela, Hutka, Peter, Ondrejka, Igor, Visnovcova, Zuzana, Funakova, Dana, Hrtanek, Igor, Ferencova, Nikola, Mlyncekova, Zuzana, Kovacova, Veronika, Macejova, Andrea, Kukucka, Tomas, Mokry, Juraj, Tonhajzerova, Ingrid

“…Relationship between depressive disorder and autonomic nervous system has been already discussed. Reduced emotional regulation is supposed to be associated…”
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Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis by Adamcakova, Jana, Balentova, Sona, Barosova, Romana, Hanusrichterova, Juliana, Mikolka, Pavol, Prso, Kristian, Mokry, Juraj, Tatarkova, Zuzana, Kalenska, Dagmar, Mokra, Daniela

“…Inhalation of silica particles causes inflammatory changes leading to fibrotizing silicosis. Considering a lack of effective therapy, and a growing information…”
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Advances in the Use of N-Acetylcysteine in Chronic Respiratory Diseases by Mokra, Daniela, Mokry, Juraj, Barosova, Romana, Hanusrichterova, Juliana

“…N-acetylcysteine (NAC) is widely used because of its mucolytic effects, taking part in the therapeutic protocols of cystic fibrosis. NAC is also administered…”
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