Search Results - "Mokoala, Kgomotso M. G"

Imaging Molecular Targets and Metabolic Pathways in Breast Cancer for Improved Clinical Management: Current Practice and Future Perspectives by Ndlovu, Honest, Lawal, Ismaheel O, Mokoala, Kgomotso M G, Sathekge, Mike M

“…Breast cancer is the most frequently diagnosed cancer and leading cause of cancer-related deaths worldwide. Timely decision-making that enables implementation…”
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Immune Checkpoints, Inhibitors and Radionuclides in Prostate Cancer: Promising Combinatorial Therapy Approach by Kgatle, Mankgopo M, Boshomane, Tebatso M G, Lawal, Ismaheel O, Mokoala, Kgomotso M G, Mokgoro, Neo P, Lourens, Nico, Kairemo, Kalevo, Zeevaart, Jan Rijn, Vorster, Mariza, Sathekge, Mike M

“…Emerging research demonstrates that co-inhibitory immune checkpoints (ICs) remain the most promising immunotherapy targets in various malignancies…”
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Principal Component Analysis Applied to Radiomics Data: Added Value for Separating Benign from Malignant Solitary Pulmonary Nodules by Bomhals, Birte, Cossement, Lara, Maes, Alex, Sathekge, Mike, Mokoala, Kgomotso M G, Sathekge, Chabi, Ghysen, Katrien, Van de Wiele, Christophe

“…Here, we report on the added value of principal component analysis applied to a dataset of texture features derived from 39 solitary pulmonary lung nodule…”
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68Ga-PSMA-11 PET/CT Initial Staging in Black and White South African Males with ISUP Grade Group 1 and 2 Prostate Adenocarcinoma by Maserumule, Letjie C., Mokoala, Kgomotso M. G., van de Wiele, Christophe, Popoola, Gbenga, Hlongwa, Khanyisile N., Ndlovu, Honest, Maes, Alex, Vorster, Mariza, Sathekge, Mike M.

“…Prostate adenocarcinoma (PCa) is a leading cause of mortality. Black males with high-risk PCa have a poorer prognosis compared to white males. Patients with…”
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The Use of 18F-FDG PET/CT Metabolic Parameters in Predicting Overall Survival in Patients Undergoing Restaging for Malignant Melanoma by Hlongwa, Khanyisile N., Mokoala, Kgomotso M. G., Matsena-Zingoni, Zvifadzo, Vorster, Mariza, Sathekge, Mike M.

“…Malignant melanoma is one of the more aggressive cancers in the skin, with an increasing incidence every year. Melanoma has a better prognosis if diagnosed…”
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Radionuclide Imaging of Invasive Fungal Disease in Immunocompromised Hosts by Lawal, Ismaheel O., Mokoala, Kgomotso M. G., Kgatle, Mankgopo M., Dierckx, Rudi A. J. O., Glaudemans, Andor W. J. M., Sathekge, Mike M., Ankrah, Alfred O.

“…Invasive fungal disease (IFD) leads to increased mortality, morbidity, and costs of treatment in patients with immunosuppressive conditions. The definitive…”
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Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act): a multicentre, retrospective study by Sathekge, Mike M, Lawal, Ismaheel O, Bal, Chandrasekhar, Bruchertseifer, Frank, Ballal, Sajana, Cardaci, Giuseppe, Davis, Cindy, Eiber, Mathias, Hekimsoy, Türkay, Knoesen, Otto, Kratochwil, Clemens, Lenzo, Nat P, Mahapane, Johncy, Maserumule, Letjie C, Mdlophane, Amanda H, Mokoala, Kgomotso M G, Ndlovu, Honest, Pant, Vineet, Rathke, Hendrik, Reed, Janet, Sen, Ishita B, Singh, Aviral, Sood, Ashwani, Tauber, Robert, Thakral, Parul, Yadav, Madhav Prasad, Morgenstern, Alfred

“…Actinium-225 (225Ac) prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) is a novel therapy for metastatic castration-resistant prostate cancer…”
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Hematologic toxicity profile and efficacy of [225Ac]Ac-PSMA-617 α-radioligand therapy of patients with extensive skeletal metastases of castration-resistant prostate cancer by Lawal, Ismaheel O., Morgenstern, Alfred, Vorster, Mariza, Knoesen, Otto, Mahapane, Johncy, Hlongwa, Khanyisile N., Maserumule, Letjie C., Ndlovu, Honest, Reed, Janet D., Popoola, Gbenga O., Mokoala, Kgomotso M. G., Mdlophane, Amanda, Bruchertseifer, Frank, Sathekge, Mike M.

“…Purpose Actinium-225-labeled prostate-specific membrane antigen ([ 225 Ac]Ac-PSMA-617) is safe and effective in the treatment of metastatic…”
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Immune reconstitution inflammatory syndrome‐associated Graves disease in HIV‐infected patients: clinical characteristics and response to radioactive iodine therapy by Lawal, Ismaheel O., Orunmuyi, Akintunde T., Popoola, Gbenga O., Mokoala, Kgomotso M. G., Lengana, TThabo, Sathekge, Mike M.

“…Objectives We aimed to describe the clinical characteristics and the response to radioactive iodine (RAI) treatment of immune reconstitution inflammatory…”
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[ 18 F]F-Poly(ADP-Ribose) Polymerase Inhibitor Radiotracers for Imaging PARP Expression and Their Potential Clinical Applications in Oncology by Ndlovu, Honest, Lawal, Ismaheel O, Mdanda, Sipho, Kgatle, Mankgopo M, Mokoala, Kgomotso M G, Al-Ibraheem, Akram, Sathekge, Mike M

“…Including poly(ADP-ribose) polymerase (PARP) inhibitors in managing patients with inoperable tumors has significantly improved outcomes. The PARP inhibitors…”
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Correlation between [ 68 Ga]Ga-FAPI-46 PET Imaging and HIF-1α Immunohistochemical Analysis in Cervical Cancer: Proof-of-Concept by Mokoala, Kgomotso M G, Lawal, Ismaheel O, Maserumule, Letjie C, Bida, Meshack, Maes, Alex, Ndlovu, Honest, Reed, Janet, Mahapane, Johncy, Davis, Cindy, Van de Wiele, Christophe, Popoola, Gbenga, Giesel, Frederik L, Vorster, Mariza, Sathekge, Mike M

“…Hypoxia leads to changes in tumor microenvironment (upregulated CAFs) with resultant aggressiveness. A key factor in the physiological response to hypoxia is…”
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A Prospective Investigation of Tumor Hypoxia Imaging with 68Ga-Nitroimidazole PET/CT in Patients with Carcinoma of the Cervix Uteri and Comparison with 18F-FDG PET/CT: Correlation with Immunohistochemistry by Mokoala, Kgomotso M. G., Lawal, Ismaheel O., Maserumule, Letjie C., Hlongwa, Khanyisile N., Ndlovu, Honest, Reed, Janet, Bida, Meshack, Maes, Alex, van de Wiele, Christophe, Mahapane, Johncy, Davis, Cindy, Jeong, Jae Min, Popoola, Gbenga, Vorster, Mariza, Sathekge, Mike M.

“…Hypoxia in cervical cancer has been associated with a poor prognosis. Over the years 68Ga labelled nitroimidazoles have been studied and have shown improved…”
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Pattern of Prostate Cancer Recurrence Assessed by 68Ga-PSMA-11 PET/CT in Men Treated with Primary Local Therapy by Lawal, Ismaheel O., Lengana, Thabo, Popoola, Gbenga O., Orunmuyi, Akintunde T., Kgatle, Mankgopo M., Mokoala, Kgomotso M. G., Sathekge, Mike M.

“…Imaging plays a vital role in detecting the recurrence of prostate cancer (PCa) to guide the choice of salvage therapy. Gallium-68 prostate-specific membrane…”
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Correlation Between CT Features of Active Tuberculosis and Residual Metabolic Activity on End-of-Treatment FDG PET/CT in Patients Treated for Pulmonary Tuberculosis by Lawal, Ismaheel O, Mokoala, Kgomotso M G, Mathebula, Matsontso, Moagi, Ingrid, Popoola, Gbenga O, Moeketsi, Nontando, Nchabeleng, Maphoshane, Hikuam, Chris, Ellner, Jerrold J, Hatherill, Mark, Fourie, Bernard P, Sathekge, Mike M

“…Patients who complete a standard course of anti-tuberculous treatment (ATT) for pulmonary tuberculosis and are declared cured according to the current standard…”
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PET/CT and SPECT/CT for Infection in Joints and Bones: An Overview and Future Directions by Mokoala, Kgomotso M G, Ndlovu, Honest, Lawal, Ismaheel, Sathekge, Mike Machaba

“…Infections of the bones and joints, if misdiagnosed, may result in serious morbidity and even mortality. A prompt diagnosis followed by appropriate management…”
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Prognostic Value of PSMA PET/CT in Prostate Cancer by Lawal, Ismaheel O, Ndlovu, Honest, Kgatle, Mankgopo, Mokoala, Kgomotso M G, Sathekge, Mike M

“…Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in the majority of prostate cancer (PCa). PSMA has an enzymatic function…”
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Nuclear Medicine Imaging of Gynecological Malignancies: The Tumor, the Tumor Microenvironment, and Beyond by Mokoala, Kgomotso M G, Sathekge, Michael M

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Prostate-specific Membrane Antigen: Alpha-labeled Radiopharmaceuticals by Ndlovu, Honest, Mokoala, Kgomotso M.G., Lawal, Ismaheel, Emmett, Louise, Sathekge, Mike M.

“…Novel prostate-specific membrane antigen (PSMA) ligands labeled with α-emitting radionuclides are sparking a growing interest in prostate cancer treatment…”
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Advances in Radioligand Theranostics in Oncology by Lawal, Ismaheel O., Abubakar, Sofiullah O., Ndlovu, Honest, Mokoala, Kgomotso M. G., More, Stuart S., Sathekge, Mike M.

“…Theranostics with radioligands (radiotheranostics) has played a pivotal role in oncology. Radiotheranostics explores the molecular targets expressed on tumor…”
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68Ga-FAPI-PET/CT in patients with various gynecological malignancies by Dendl, Katharina, Koerber, Stefan A., Finck, Rebecca, Mokoala, Kgomotso M. G., Staudinger, Fabian, Schillings, Lisa, Heger, Ulrike, Röhrich, Manuel, Kratochwil, Clemens, Sathekge, Mike, Jäger, Dirk, Debus, Jürgen, Haberkorn, Uwe, Giesel, Frederik L.

“…Purpose 68 Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective…”
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