Search Results - "Moklas, Mohamad Aris Mohd"
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Transient prenatal ruxolitinib treatment suppresses astrogenesis during development and improves learning and memory in adult mice
Published in Scientific reports (15-02-2021)“…Ruxolitinib is the first janus kinase 1 (JAK1) and JAK2 inhibitor that was approved by the United States Food and Drug Administration (FDA) agency for the…”
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Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approaches
Published in Biomedicine & pharmacotherapy (01-01-2019)“…[Display omitted] •D-galactose 60/AlCl3 200(mg/kg.bw) induced cognitive deficits in rats.•Neurodegeneration was observed in the demented rats.•Centella…”
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Anticancer Molecular Mechanism of Protocatechuic Acid Loaded on Folate Coated Functionalized Graphene Oxide Nanocomposite Delivery System in Human Hepatocellular Carcinoma
Published in Materials (09-02-2021)“…Liver cancer is listed as the fifth-ranked cancer, responsible for 9.1% of all cancer deaths globally due to its assertive nature and poor survival rate. To…”
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4
Morphological Changes and Cellular Uptake of Functionalized Graphene Oxide Loaded with Protocatechuic Acid and Folic Acid in Hepatocellular Carcinoma Cancer Cell
Published in International journal of molecular sciences (16-08-2020)“…The development of nanocomposites has swiftly changed the horizon of drug delivery systems in defining a new platform. Major understanding of the interaction…”
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5
Antioxidant Properties of Crude Extract, Partition Extract, and Fermented Medium of Dendrobium sabin Flower
Published in Evidence-based complementary and alternative medicine (01-01-2017)“…Antioxidant properties of crude extract, partition extract, and fermented medium from Dendrobium sabin (DS) flower were investigated. The oven-dried DS flower…”
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The Role of Piper sarmentosum Aqueous Extract as a Bone Protective Agent, a Histomorphometric Study
Published in International journal of molecular sciences (19-10-2020)“…Glucocorticoids are one of the causes of secondary osteoporosis. The aqueous extract of contains flavonoids that possess antioxidant effects. In this study, we…”
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Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Nootropics or smart drugs are well-known compounds or supplements that enhance the cognitive performance. They work by increasing the mental function such as…”
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Cockle Shell-Derived Calcium Carbonate (Aragonite) Nanoparticles: A Dynamite to Nanomedicine
Published in Applied sciences (01-07-2019)“…Cockle shell is an external covering of small, salt water edible clams (Anadara granosa) that dwells in coastal area. This abundant biomaterial is hard, cheap…”
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Antioxidant and anti-inflammatory properties of Erythroxylum cuneatum alkaloid leaf extract
Published in Heliyon (01-06-2020)“…Erythroxylum cuneatum (E. cuneatum) which belongs to Erythroxylaceae family is a tropical flowering plant from the genus of Erythroxylum. It is used in…”
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Regulatory role of the endocannabinoid system on glial cells toward cognitive function in Alzheimer's disease: A systematic review and meta-analysis of animal studies
Published in Frontiers in pharmacology (03-03-2023)“…Over the last decade, researchers have sought to develop novel medications against dementia. One potential agent under investigation is cannabinoids. This…”
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A Review on the Prevalence of Toxoplasma gondii in Humans and Animals Reported in Malaysia from 2008-2018
Published in International journal of environmental research and public health (03-07-2020)“…Toxoplasmosis is a disease caused by the protozoan parasite ( ). Human toxoplasmosis seroprevalence in Malaysia has increased since it was first reported in…”
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Curcumin‐loaded cockle shell‐derived calcium carbonate nanoparticles ameliorates lead‐induced neurotoxicity in rats via attenuation of oxidative stress
Published in Food science & nutrition (01-05-2023)“…A substantial global health burden is associated with neurotoxicity caused by lead (Pb) exposure and the common mechanism of this toxicity is mainly via…”
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Menhaden fish oil attenuates postpartum depression in rat model via inhibition of NLRP3-inflammasome driven inflammatory pathway
Published in Journal of Traditional and Complementary Medicine (01-09-2021)“…Background and aim: Postpartum depression (PPD) is a familiar problem which is associated with about 10-20% of women after child delivery. Fish oil (FO) has a…”
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Neuroprotective roles of flavonoid "hispidulin" in the central nervous system: A review
Published in Iranian journal of basic medical sciences (01-01-2024)“…Interest in naturally occurring phytochemicals has been on the increase, they are believed to reduce the risk of brain disorders. Hispidulin (HN) is a phenolic…”
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Toxoplasma gondii induced cognitive impairment in rats via dysregulation of dopamine receptors and indoleamine 2,3 dioxygenase
Published in Heliyon (01-03-2023)“…Toxoplasma gondii (T. gondii) is a parasite capable of residing in the brain of their host which influences behaviour changes due to alterations in the…”
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WIN55,212-2 Attenuates Cognitive Impairments in AlCl3 + d-Galactose-Induced Alzheimer’s Disease Rats by Enhancing Neurogenesis and Reversing Oxidative Stress
Published in Biomedicines (19-09-2021)“…Neurotransmission and cognitive dysfunctions have been linked to old age disorders including Alzheimer’s disease (AD). Aluminium is a known neurotoxic metal,…”
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Molecular Detection and Genetic Diversity of Toxoplasma gondii Oocysts in Cat Faeces from Klang Valley, Malaysia, Using B1 and REP Genes in 2018
Published in Pathogens (Basel) (16-07-2020)“…The major route for ( ) infection is through the ingestion of foods contaminated with oocyst from cat faeces. The microscopic detection of oocysts in cat…”
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Antidepressant-Like Properties of Fish Oil on Postpartum Depression-Like Rats Model: Involvement of Serotonergic System
Published in Brain sciences (01-10-2020)“…Pathophysiology of postpartum depression (PPD) has been associated with many factors, such as neuroendocrine, neuroinflammation and neurotransmitter changes…”
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Morphine Antidependence of Erythroxylum cuneatum (Miq.) Kurz in Neurotransmission Processes In Vitro
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Opiate abuse has been studied to cause adaptive changes observed in the presynaptic release and the mediated-synaptic plasticity proteins. The involvement of…”
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d-galactose and aluminium chloride induced rat model with cognitive impairments
Published in Biomedicine & pharmacotherapy (01-07-2018)“…[Display omitted] •Combined d-galactose 60/AlCl3 200(mg/kg.bw) alter cognitive functions in rats.•Neuronal degeneration was observed at the subfields of the…”
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