Search Results - "Mokhosoev, Innokenty M."
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Metabolic Heterogeneity of Cancer Cells: An Interplay between HIF-1, GLUTs, and AMPK
Published in Cancers (02-04-2020)“…It has been long recognized that cancer cells reprogram their metabolism under hypoxia conditions due to a shift from oxidative phosphorylation (OXPHOS) to…”
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Oxidative Stress and Advanced Lipoxidation and Glycation End Products (ALEs and AGEs) in Aging and Age-Related Diseases
Published in Oxidative medicine and cellular longevity (2019)“…Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living organisms and is denoted as a persistent condition of an imbalance…”
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Proteomic Profiling and Artificial Intelligence for Hepatocellular Carcinoma Translational Medicine
Published in Biomedicines (06-02-2021)“…Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver with high morbidity and mortality rates worldwide. Since 1963, when…”
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Short Linear Motifs Orchestrate Functioning of Human Proteins during Embryonic Development, Redox Regulation, and Cancer
Published in Metabolites (21-05-2022)“…Short linear motifs (SLiMs) are evolutionarily conserved functional modules of proteins that represent amino acid stretches composed of 3 to 10 residues. The…”
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Pregnancy-Specific β1-Glycoproteins: Combined Biomarker Roles, Structure/Function Relationships and Implications for Drug Design
Published in Current medicinal chemistry (01-01-2017)“…Pregnancy specific β1-glycoproteins (PSGs) have long been recognized as trophoblast quality and embryo viability markers. However, biological roles of PSGs…”
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Cytochrome P450 monooxygenase systems: Diversity and plasticity for adaptive stress response
Published in Progress in biophysics and molecular biology (01-11-2024)“…Superfamily of cytochromes P450 (CYPs) is composed of heme-thiolate-containing monooxygenase enzymes, which play crucial roles in the biosynthesis,…”
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Predictive biomarkers for systemic therapy of hepatocellular carcinoma
Published in Expert review of molecular diagnostics (02-11-2021)“…Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third cancer-related cause of death worldwide. In recent years, several systemic…”
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Human EGF-derived direct and reverse short linear motifs: conformational dynamics insight into the receptor-binding residues
Published in Journal of biomolecular structure & dynamics (04-04-2018)“…Short linear motifs (SLiMs) have been recognized to perform diverse functions in a variety of regulatory proteins through the involvement in protein-protein…”
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