Search Results - "Mokhonova, Ekaterina I"

The Development of Robust Antibodies to Sarcospan, a Dystrophin- and Integrin-Associated Protein, for Basic and Translational Research by Mokhonova, Ekaterina I, Malik, Ravinder, Mamsa, Hafsa, Walker, Jackson, Gibbs, Elizabeth M, Crosbie, Rachelle H

“…Sarcospan (SSPN) is a 25-kDa transmembrane protein that is broadly expressed at the cell surface of many tissues, including, but not limited to, the myofibers…”
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Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy by Kendall, Genevieve C, Mokhonova, Ekaterina I, Moran, Miriana, Sejbuk, Natalia E, Wang, Derek W, Silva, Oscar, Wang, Richard T, Martinez, Leonel, Lu, Qi L, Damoiseaux, Robert, Spencer, Melissa J, Nelson, Stanley F, Miceli, M Carrie

“…Duchenne muscular dystrophy (DMD) causes profound and progressive muscle weakness and loss, resulting in early death. DMD is usually caused by frameshifting…”
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Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue by Scripture-Adams, Deirdre D., Chesmore, Kevin N., Barthélémy, Florian, Wang, Richard T., Nieves-Rodriguez, Shirley, Wang, Derek W., Mokhonova, Ekaterina I., Douine, Emilie D., Wan, Jijun, Little, Isaiah, Rabichow, Laura N., Nelson, Stanley F., Miceli, M. Carrie

“…In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage, dysregulation of repair, fibro-fatty replacement, and weakness. We develop…”
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Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse by Wang, Derek W., Mokhonova, Ekaterina I., Kendall, Genevieve C., Becerra, Diana, Naeini, Yalda B., Cantor, Rita M., Spencer, Melissa J., Nelson, Stanley F., Miceli, M. Carrie

“…Duchenne muscular dystrophy (DMD) is caused by mutations in DMD, resulting in loss of dystrophin, which is essential to muscle health. DMD “exon skipping” uses…”
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Role of the membrane fusion protein in the assembly of resistance-nodulation-cell division multidrug efflux pump in Pseudomonas aeruginosa by Mokhonov, Vladislav V., Mokhonova, Ekaterina I., Akama, Hiroyuki, Nakae, Taiji

“…The tripartite xenobiotic–antibiotic transporter of Pseudomonas aeruginosa consists of the inner membrane transporter (e.g., MexB, MexY), the periplasmic…”
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The E3 ubiquitin ligase TRIM32 regulates myoblast proliferation by controlling turnover of NDRG2 by Mokhonova, Ekaterina I, Avliyakulov, Nuraly K, Kramerova, Irina, Kudryashova, Elena, Haykinson, Michael J, Spencer, Melissa J

“…Limb girdle muscular dystrophy 2H is caused by mutations in the gene encoding the E3 ubiquitin ligase, TRIM32. Previously, we generated and characterized a…”
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Kunjin replicon-based simian immunodeficiency virus gag vaccines by Anraku, Itaru, Mokhonov, Vladislav V, Rattanasena, Paweena, Mokhonova, Ekaterina I, Leung, Jason, Pijlman, Gorben, Cara, Andrea, Schroder, Wayne A, Khromykh, Alexander A, Suhrbier, Andreas

“…Abstract An RNA-based, non-cytopathic replicon vector system, based on the flavivirus Kunjin, has shown considerable promise as a new vaccine delivery system…”
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Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques by Kent, Stephen J, De Rose, Robert, Mokhonov, Vlad V, Mokhonova, Ekaterina I, Fernandez, Caroline S, Alcantara, Sheilajen, Rollman, Erik, Mason, Rosemarie D, Loh, Liyen, Peut, Viv, Reece, Jeanette C, Wang, Xiang Ju, Wilson, Kim M, Suhrbier, Andreas, Khromykh, Alexander

“…Abstract Persistent gag-specific T cell immunity would be a useful component of an effective HIV vaccine. The Flavivirus Kunjin replicon was previously…”
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Forceful large-scale expression of “problematic” membrane proteins by Mokhonova, Ekaterina I., Mokhonov, Vladislav V., Akama, Hiroyuki, Nakae, Taiji

“…We developed an Escherichia coli expression system for overproduction of a highly toxic membrane protein that is impossible to overexpress by traditionally…”
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Kunjin replicon-based simian immunodeficiency virusgagvaccines by Anraku, Itaru, Mokhonov, Vladislav V, Rattanasena, Paweena, Mokhonova, Ekaterina I, Leung, Jason, Pijlman, Gorben, Cara, Andrea, Schroder, Wayne A, Khromykh, Alexander A, Suhrbier, Andreas

“…An RNA-based, non-cytopathic replicon vector system, based on the flavivirus Kunjin, has shown considerable promise as a new vaccine delivery system. Here we…”
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