Search Results - "Mok, T. C."

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives by Huang, Bei, Chau, Steven W. H., Liu, Yaping, Chan, Joey W. Y., Wang, Jing, Ma, Suk Ling, Zhang, Jihui, Chan, Paul K. S., Yeoh, Yun Kit, Chen, Zigui, Zhou, Li, Wong, Sunny Hei, Mok, Vincent C. T., To, Ka Fai, Lai, Hei Ming, Ng, Simon, Trenkwalder, Claudia, Chan, Francis K. L., Wing, Yun Kwok

“…The microbiota-gut-brain axis has been suggested to play an important role in Parkinson’s disease (PD). Here we performed a cross-sectional study to profile…”
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Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain by Zhao, Lei, Li, Zhongqi, Vong, Joaquim S. L., Chen, Xinyi, Lai, Hei-Ming, Yan, Leo Y. C., Huang, Junzhe, Sy, Samuel K. H., Tian, Xiaoyu, Huang, Yu, Chan, Ho Yin Edwin, So, Hon-Cheong, Ng, Wai-Lung, Tang, Yamei, Lin, Wei-Jye, Mok, Vincent C. T., Ko, Ho

“…The molecular signatures of cells in the brain have been revealed in unprecedented detail, yet the ageing-associated genome-wide expression changes that may…”
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LC–MS-Based Urinary Metabolite Signatures in Idiopathic Parkinson’s Disease by Luan, Hemi, Liu, Liang-Feng, Meng, Nan, Tang, Zhi, Chua, Ka-Kit, Chen, Lei-Lei, Song, Ju-Xian, Mok, Vincent C. T, Xie, Li-Xia, Li, Min, Cai, Zongwei

“…Increasing evidence has shown that abnormal metabolic phenotypes in body fluids reflect the pathogenesis and pathophysiology of Parkinson’s disease (PD). These…”
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Anomalous Light Scattering by Topological PT-symmetric Particle Arrays by Ling, C. W., Choi, Ka Hei, Mok, T. C., Zhang, Zhao-Qing, Fung, Kin Hung

“…Robust topological edge modes may evolve into complex-frequency modes when a physical system becomes non-Hermitian. We show that, while having negligible…”
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Construction of brain atlases based on a multi-center MRI dataset of 2020 Chinese adults by Liang, Peipeng, Shi, Lin, Chen, Nan, Luo, Yishan, Wang, Xing, Liu, Kai, Mok, Vincent CT, Chu, Winnie CW, Wang, Defeng, Li, Kuncheng

“…Despite the known morphological differences (e.g., brain shape and size) in the brains of populations of different origins (e.g., age and race), the Chinese…”
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Author Correction: An optofluidic platform for interrogating chemosensory behavior and brainwide neural representation in larval zebrafish by Sy, Samuel K. H., Chan, Danny C. W., Chan, Roy C. H., Lyu, Jing, Li, Zhongqi, Wong, Kenneth K. Y., Choi, Chung Hang Jonathan, Mok, Vincent C. T., Lai, Hei-Ming, Randlett, Owen, Hu, Yu, Ko, Ho

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An optofluidic platform for interrogating chemosensory behavior and brainwide neural representation in larval zebrafish by Sy, Samuel K. H., Chan, Danny C. W., Chan, Roy C. H., Lyu, Jing, Li, Zhongqi, Wong, Kenneth K. Y., Choi, Chung Hang Jonathan, Mok, Vincent C. T., Lai, Hei-Ming, Randlett, Owen, Hu, Yu, Ko, Ho

“…Studying chemosensory processing desires precise chemical cue presentation, behavioral response monitoring, and large-scale neuronal activity recording. Here…”
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Automatic Segmentation of Acute Ischemic Stroke From DWI Using 3-D Fully Convolutional DenseNets by Zhang, Rongzhao, Zhao, Lei, Lou, Wutao, Abrigo, Jill M., Mok, Vincent C. T., Chu, Winnie C. W., Wang, Defeng, Shi, Lin

“…Acute ischemic stroke is recognized as a common cerebral vascular disease in aging people. Accurate diagnosis and timely treatment can effectively improve the…”
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Effects of functional tasks exercise on cognitive functions of older adults with mild cognitive impairment: a randomized controlled pilot trial by Law, Lawla L F, Mok, Vincent C T, Yau, Matthew M K

“…Dementia has been presenting an imminent public health challenge worldwide. Studies have shown a combination of cognitive and physical trainings may have…”
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An MRI-based strategy for differentiation of frontotemporal dementia and Alzheimer's disease by Yu, Qun, Mai, Yingren, Ruan, Yuting, Luo, Yishan, Zhao, Lei, Fang, Wenli, Cao, Zhiyu, Li, Yi, Liao, Wang, Xiao, Songhua, Mok, Vincent C T, Shi, Lin, Liu, Jun

“…The differential diagnosis of frontotemporal dementia (FTD) and Alzheimer's disease (AD) is difficult due to the overlaps of clinical symptoms. Structural…”
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Evaluation of oropharyngeal deglutitive pressure dynamics in patients with Parkinson's disease by Szczesniak, Michal M, Omari, Taher I, Lam, Thomas Y, Wong, Marc, Mok, Vincent C T, Wu, Justin C Y, Chiu, Philip W Y, Yuen, Margaret T Y, Tsang, Raymond K, Cock, Charles, Sung, Joseph J, Wu, Peter

“…In Parkinson's disease (PD), oropharyngeal dysphagia is common and clinically relevant. The neurophysiology of dysphagia in PD is complex and incompletely…”
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Evolution of intracranial atherosclerotic disease under modern medical therapy by Leung, Thomas W., Wang, Lily, Soo, Yannie O. Y., Ip, Vincent H. L., Chan, Anne Y. Y., Au, Lisa W. C., Fan, Florence S. Y., Lau, Alex Y. L., Leung, Howan, Abrigo, Jill, Wong, Adrian, Mok, Vincent C. T., Ng, Ping Wing, Tsoi, Tak Hong, Li, Siu Hung, Man, Celeste B. L., Fong, Wing Chi, Wong, Ka Sing, Yu, Simon C. H.

“…Objective Understanding how symptomatic intracranial atherosclerotic disease (ICAD) evolves with current medical therapy may inform secondary stroke…”
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Neuropsychiatric Symptom Clusters in Stroke and Transient Ischemic Attack by Cognitive Status and Stroke Subtype: Frequency and Relationships with Vascular Lesions, Brain Atrophy and Amyloid by Wong, Adrian, Lau, Alexander Y L, Yang, Jie, Wang, Zhaolu, Liu, Wenyan, Lam, Bonnie Y K, Au, Lisa, Shi, Lin, Wang, Defeng, Chu, Winnie C W, Xiong, Yun-Yun, Lo, Eugene S K, Law, Lorraine S N, Leung, Thomas W H, Lam, Linda C W, Chan, Anne Y Y, Soo, Yannie O Y, Leung, Eric Y L, Wong, Lawrence K S, Mok, Vincent C T

“…The objectives of this study are 1) to examine the frequencies of neuropsychiatric symptom clusters in patients with stroke or transient ischemic attack (TIA)…”
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Hemodynamics and stroke risk in intracranial atherosclerotic disease by Leng, Xinyi, Lan, Linfang, Ip, Hing Lung, Abrigo, Jill, Scalzo, Fabien, Liu, Haipeng, Feng, Xueyan, Chan, Ka Lung, Fan, Florence S. Y., Ma, Sze Ho, Fang, Hui, Xu, Yuming, Li, Jingwei, Zhang, Bing, Xu, Yun, Soo, Yannie O. Y., Mok, Vincent C. T., Yu, Simon C. H., Liebeskind, David S., Wong, Ka Sing, Leung, Thomas W.

“…Objective To investigate whether hemodynamic features of symptomatic intracranial atherosclerotic stenosis (sICAS) might correlate with the risk of stroke…”
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Relations between Recent Past Leisure Activities with Risks of Dementia and Cognitive Functions after Stroke by Wong, Adrian, Lau, Alexander Y L, Lo, Eugene, Tang, Michael, Wang, Zhaolu, Liu, Wenyan, Tanner, Nicole, Chau, Natalie, Law, Lorraine, Shi, Lin, Chu, Winnie C W, Yang, Jie, Xiong, Yun-Yun, Lam, Bonnie Y K, Au, Lisa, Chan, Anne Y Y, Soo, Yannie, Leung, Thomas W H, Wong, Lawrence K S, Lam, Linda C W, Mok, Vincent C T

“…Leisure activity participation has been shown to lower risks of cognitive decline in non-stroke populations. However, effects of leisure activities…”
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The validity, reliability and clinical utility of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease by Wong, Adrian, Xiong, Yun Y, Kwan, Pauline W L, Chan, Anne Y Y, Lam, Wynnie W M, Wang, Ki, Chu, Winnie C W, Nyenhuis, David L, Nasreddine, Ziad, Wong, Lawrence K S, Mok, Vincent C T

“…To evaluate the psychometric properties of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease (SVD). 40 SVD…”
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Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner by Li, Zhongqi, Chen, Xinyi, Vong, Joaquim S. L., Zhao, Lei, Huang, Junzhe, Yan, Leo Y. C., Ip, Bonaventure, Wing, Yun Kwok, Lai, Hei-Ming, Mok, Vincent C. T., Ko, Ho

“…Pharmacological reversal of brain aging is a long-sought yet challenging strategy for the prevention and treatment of age-related neurodegeneration, due to the…”
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The prognosis of acute symptomatic seizures after ischaemic stroke by Leung, Thomas, Leung, Howan, Soo, Yannie O Y, Mok, Vincent C T, Wong, K S

“…ObjectiveAcute symptomatic seizure (AS) after ischaemic stroke is defined as a seizure occurring ≤7 days of the stroke. There remains a lack of information on…”
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A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study by Cheung, Carol Y, Ran, An Ran, Wang, Shujun, Chan, Victor T T, Sham, Kaiser, Hilal, Saima, Venketasubramanian, Narayanaswamy, Cheng, Ching-Yu, Sabanayagam, Charumathi, Tham, Yih Chung, Schmetterer, Leopold, McKay, Gareth J, Williams, Michael A, Wong, Adrian, Au, Lisa W C, Lu, Zhihui, Yam, Jason C, Tham, Clement C, Chen, John J, Dumitrascu, Oana M, Heng, Pheng-Ann, Kwok, Timothy C Y, Mok, Vincent C T, Milea, Dan, Chen, Christopher Li-Hsian, Wong, Tien Yin

“…There is no simple model to screen for Alzheimer's disease, partly because the diagnosis of Alzheimer's disease itself is complex-typically involving expensive…”
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Histogram-based normalization technique on human brain magnetic resonance images from different acquisitions by Sun, Xiaofei, Shi, Lin, Luo, Yishan, Yang, Wei, Li, Hongpeng, Liang, Peipeng, Li, Kuncheng, Mok, Vincent C T, Chu, Winnie C W, Wang, Defeng

“…Intensity normalization is an important preprocessing step in brain magnetic resonance image (MRI) analysis. During MR image acquisition, different scanners or…”
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