Search Results - "Mojzych, Mariusz"

Focus on UV-Induced DNA Damage and Repair-Disease Relevance and Protective Strategies by Kciuk, Mateusz, Marciniak, Beata, Mojzych, Mariusz, Kontek, Renata

“…The protective ozone layer is continually depleting due to the release of deteriorating environmental pollutants. The diminished ozone layer contributes to…”
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CD200:CD200R Interactions and Their Importance in Immunoregulation by Kotwica-Mojzych, Katarzyna, Jodłowska-Jędrych, Barbara, Mojzych, Mariusz

“…The molecule CD200, described many years ago as a naturally occurring immunomodulatory agent, capable of regulating inflammation and transplant rejection, has…”
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Metastasis and MAPK Pathways by Kciuk, Mateusz, Gielecińska, Adrianna, Budzinska, Adrianna, Mojzych, Mariusz, Kontek, Renata

“…Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is limited due to the metastasis of cells to distant locations of the…”
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Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives by Tahir, Tehreem, Ashfaq, Muhammad, Saleem, Muhammad, Rafiq, Muhammad, Shahzad, Mirza Imran, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have…”
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Targeting carbonic anhydrase IX and XII isoforms with small molecule inhibitors and monoclonal antibodies by Kciuk, Mateusz, Gielecińska, Adrianna, Mujwar, Somdutt, Mojzych, Mariusz, Marciniak, Beata, Drozda, Rafał, Kontek, Renata

“…Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins that catalyze a very basic but crucial physiological reaction: the…”
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Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto-1,2,4-triazole by Shahzadi, Irum, Zahoor, Ameer Fawad, Tüzün, Burak, Mansha, Asim, Anjum, Muhammad Naveed, Rasul, Azhar, Irfan, Ali, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been synthesized and evaluated against human liver cancer cell line (Hep G2)…”
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Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as Novel Potential Anticancer Agents: Cytotoxic and Genotoxic Activities In Vitro by Bukowski, Karol, Marciniak, Beata, Kciuk, Mateusz, Mojzych, Mariusz, Kontek, Renata

“…In this paper, we present for the first time the evaluation of cytotoxicity and genotoxicity of de novo synthesized…”
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The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3- e ]tetrazolo[4,5- b ][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells by Gornowicz, Agnieszka, Szymanowska, Anna, Mojzych, Mariusz, Bielawski, Krzysztof, Bielawska, Anna

“…The discovery of cytotoxic drugs is focused on designing a compound structure that directly affects cancer cells without an impact on normal cells. The…”
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Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3- e ][1,2,4]triazine Derivatives by Bernat, Zofia, Szymanowska, Anna, Kciuk, Mateusz, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…This review focuses on the cytotoxic effect of new synthetic pyrazolo[4,3- ][1,2,4]triazine derivatives against different tumor cell lines. Some annulated…”
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The Anticancer Action of a Novel 1,2,4-Triazine Sulfonamide Derivative in Colon Cancer Cells by Gornowicz, Agnieszka, Szymanowska, Anna, Mojzych, Mariusz, Czarnomysy, Robert, Bielawski, Krzysztof, Bielawska, Anna

“…Cancer therapy is one of the most important challenges of modern medical and chemical sciences. Among the many methods of combating cancer, chemotherapy plays…”
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Mitsunobu Reaction: A Powerful Tool for the Synthesis of Natural Products: A Review by Munawar, Saba, Zahoor, Ameer Fawad, Ali, Shafaqat, Javed, Sadia, Irfan, Muhammad, Irfan, Ali, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…The Mitsunobu reaction plays a vital part in organic chemistry due to its wide synthetic applications. It is considered as a significant reaction for the…”
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An Update on Synthesis of Coumarin Sulfonamides as Enzyme Inhibitors and Anticancer Agents by Rubab, Laila, Afroz, Sumbal, Ahmad, Sajjad, Hussain, Saddam, Nawaz, Iram, Irfan, Ali, Batool, Fozia, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Coumarin is an important six-membered aromatic heterocyclic pharmacophore, widely distributed in natural products and synthetic molecules. The versatile and…”
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Cyclin-Dependent Kinase Synthetic Lethality Partners in DNA Damage Response by Kciuk, Mateusz, Gielecińska, Adrianna, Mujwar, Somdutt, Mojzych, Mariusz, Kontek, Renata

“…Cyclin-dependent kinases (CDKs) are pivotal mediators and effectors of the DNA damage response (DDR) that regulate both the pathway components and proteins…”
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Exploring the Synergistic Anticancer Potential of Benzofuran-Oxadiazoles and Triazoles: Improved Ultrasound- and Microwave-Assisted Synthesis, Molecular Docking, Hemolytic, Thrombolytic and Anticancer Evaluation of Furan-Based Molecules by Irfan, Ali, Faiz, Sadia, Rasul, Azhar, Zafar, Rehman, Zahoor, Ameer Fawad, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Ultrasound- and microwave-assisted green synthetic strategies were applied to furnish benzofuran-oxadiazole - and benzofuran-triazole - derivatives in good to…”
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Pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine Sulfonamides as Novel Potential Anticancer Agents: Apoptosis, Oxidative Stress, and Cell Cycle Analysis by Bukowski, Karol, Marciniak, Beata, Kciuk, Mateusz, Mujwar, Somdutt, Mojzych, Mariusz, Kontek, Renata

“…The current study continues the evaluation of the anticancer potential of three de novo synthesized pyrazolo[4,3- ]tetrazolo[1,5- ][1,2,4]triazine…”
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Reactivity of heterocyclic α-aminomethylsilanes with alcohols by Pypowski, Krzysztof, Mojzych, Mariusz

“…Alkoxylation of N -substituted heterocyclic aminomethylsilyl moieties was studied using primary and tertiary alcohols. The reaction of…”
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The power of pomegranate as natural supplement remedy for sportsmen and athletes: A systematic review and meta-analysis by Bibi, Jannat, Lei, Yao, Kotwica-Mojzych, Katarzyna, Głowacka, Mariola, Mojzych, Mariusz

“…[Display omitted] •Pomegranate, has recognized health benefits but its effect on exercise performance and recovery is debated.•Results suggested pomegranate…”
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Transition Metal Catalyzed Hiyama Cross-Coupling: Recent Methodology Developments and Synthetic Applications by Noor, Rida, Zahoor, Ameer Fawad, Irfan, Muhammad, Hussain, Syed Makhdoom, Ahmad, Sajjad, Irfan, Ali, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Hiyama cross-coupling is a versatile reaction in synthetic organic chemistry for the construction of carbon–carbon bonds. It involves the coupling of…”
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Pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine Sulfonamides as an Important Scaffold for Anticancer Drug Discovery-In Vitro and In Silico Evaluation by Kciuk, Mateusz, Marciniak, Beata, Celik, Ismail, Zerroug, Enfale, Dubey, Amit, Sundaraj, Rajamanikandan, Mujwar, Somdutt, Bukowski, Karol, Mojzych, Mariusz, Kontek, Renata

“…Pyrazolo[4,3- ]tetrazolo[1,5- ][1,2,4]triazine sulfonamides ( -compounds) are a relatively new class of heterocyclic compounds that exhibit a wide variety of…”
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The activity of pyrazolo[4,3- e ][1,2,4]triazine and pyrazolo[4,3- e ]tetrazolo[1,5- b ][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures by Szymanowska, Anna, Radomska, Dominika, Czarnomysy, Robert, Mojzych, Mariusz, Kotwica-Mojzych, Katarzyna, Bielawski, Krzysztof, Bielawska, Anna

“…In the last decade, an increasing interest in compounds containing pyrazolo[4,3- ][1,2,4]triazine moiety is observed. Therefore, the aim of the research was to…”
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