Search Results - "Mojica, María F"

Microbiological and Clinical Aspects of Raoultella spp by Appel, Tobias M., Quijano-Martínez, Natalia, De La Cadena, Elsa, Mojica, María F., Villegas, María Virginia

“…The genus Raoultella was established in 2001. Species of Raoultella and Klebsiella share many ecological, biochemical, clinical, and microbiological features…”
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Molecular correlates of the spread of KPC-producing Enterobacteriaceae in Colombia by Mojica, María F, Correa, Adriana, Vargas, Deninson A, Maya, Juan J, Montealegre, María C, Rojas, Laura J, Ruiz, Sory J, Quinn, John P, Villegas, María V

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B1-Metallo-β-Lactamases: Where Do We Stand? by Mojica, Maria F, Bonomo, Robert A, Fast, Walter

“…Metallo-β-Lactamases (MBLs) are class Bβ-lactamases that hydrolyze almost all clinically-availableβ-lactam antibiotics. MBLs feature the distinctive αβ/βα…”
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Genetic Basis for In Vivo Daptomycin Resistance in Enterococci by Arias, Cesar A, Panesso, Diana, McGrath, Danielle M, Qin, Xiang, Mojica, Maria F, Miller, Corwin, Diaz, Lorena, Tran, Truc T, Rincon, Sandra, Barbu, E. Magda, Reyes, Jinnethe, Roh, Jung H, Lobos, Elizabeth, Sodergren, Erica, Pasqualini, Renata, Arap, Wadih, Quinn, John P, Shamoo, Yousif, Murray, Barbara E, Weinstock, George M

“…Daptomycin is a novel antimicrobial agent with activity against vancomycin-resistant enterococci. In this report, the authors elucidate the mechanism of…”
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Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics by Galdadas, Ioannis, Qu, Shen, Oliveira, Ana Sofia F, Olehnovics, Edgar, Mack, Andrew R, Mojica, Maria F, Agarwal, Pratul K, Tooke, Catherine L, Gervasio, Francesco Luigi, Spencer, James, Bonomo, Robert A, Mulholland, Adrian J, Haider, Shozeb

“…Understanding allostery in enzymes and tools to identify it offer promising alternative strategies to inhibitor development. Through a combination of…”
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Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States by Mojica, Maria F, Rutter, Joseph D, Taracila, Magdalena, Abriata, Luciano A, Fouts, Derrick E, Papp-Wallace, Krisztina M, Walsh, Thomas J, LiPuma, John J, Vila, Alejandro J, Bonomo, Robert A

“…is a Gram-negative, nonfermenting, environmental bacillus that is an important cause of nosocomial infections, primarily associated with the respiratory tract…”
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The Reaction Mechanism of Metallo-β-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop by Palacios, Antonela R, Mojica, María F, Giannini, Estefanía, Taracila, Magdalena A, Bethel, Christopher R, Alzari, Pedro M, Otero, Lisandro H, Klinke, Sebastián, Llarrull, Leticia I, Bonomo, Robert A, Vila, Alejandro J

“…Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant…”
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Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses by Alsenani, Tahani A, Rodríguez, María Margarita, Ghiglione, Barbara, Taracila, Magdalena A, Mojica, Maria F, Rojas, Laura J, Hujer, Andrea M, Gutkind, Gabriel, Bethel, Christopher R, Rather, Philip N, Introvigne, Maria Luisa, Prati, Fabio, Caselli, Emilia, Power, Pablo, van den Akker, Focco, Bonomo, Robert A

“…Design of novel β-lactamase inhibitors (BLIs) is one of the currently accepted strategies to combat the threat of cephalosporin and carbapenem resistance in…”
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Molecular mechanisms leading to ceftolozane/tazobactam resistance in clinical isolates of Pseudomonas aeruginosa from five Latin American countries by Mojica, María F., De La Cadena, Elsa, Ríos, Rafael, García-Betancur, Juan Carlos, Díaz, Lorena, Reyes, Jinnethe, Hernández-Gómez, Cristhian, Radice, Marcela, Gales, Ana C., Castañeda Méndez, Paulo, Munita, José M., Pallares, Christian José, Martínez, José R. W., Villegas, María Virginia

“…Objectives Identify molecular mechanisms responsible for the in vitro non-susceptibility to ceftolozane/tazobactam (TOL) in a group of 158 clinical isolates of…”
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Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase by Zhao, Zhuoran, Shen, Xiayu, Chen, Shuang, Gu, Jing, Wang, Haun, Mojica, Maria F, Samanta, Moumita, Bhowmik, Debsindhu, Vila, Alejandro J, Bonomo, Robert A, Haider, Shozeb

“…β-Lactam antibiotics are the most important and widely used antibacterial agents across the world. However, the widespread dissemination of β-lactamases among…”
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Cefepime-taniborbactam demonstrates potent in vitro activity vs Enterobacterales with blaOXA-48 by Mojica, Maria F., Zeiser, Elise T., Becka, Scott A., Six, David A., Moeck, Greg, Papp-Wallace, Krisztina M.

“…Taniborbactam (formerly VNRX-5133) is a novel, investigational boronic acid β-lactamase inhibitor. The combination of cefepime (FEP) with taniborbactam is…”
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Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM‑1 Carbapenemase by González, Mariano M, Kosmopoulou, Magda, Mojica, Maria F, Castillo, Valerie, Hinchliffe, Philip, Pettinati, Ilaria, Brem, Jürgen, Schofield, Christopher J, Mahler, Graciela, Bonomo, Robert A, Llarrull, Leticia I, Spencer, James, Vila, Alejandro J

“…Pathogenic Gram-negative bacteria resistant to almost all β-lactam antibiotics are a major public health threat. Zn­(II)-dependent or metallo-β-lactamases…”
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Comparative In Vitro Activity of Ceftolozane/Tazobactam against Clinical Isolates of Pseudomonas aeruginosa and Enterobacterales from Five Latin American Countries by García-Betancur, Juan Carlos, De La Cadena, Elsa, Mojica, María F., Hernández-Gómez, Cristhian, Correa, Adriana, Radice, Marcela A., Castañeda-Méndez, Paulo, Jaime-Villalon, Diego A., Gales, Ana C., Munita, José M., Villegas, María Virginia

“…Background: Ceftolozane/tazobactam (C/T) is a combination of an antipseudomonal oxyiminoaminothiazolyl cephalosporin with potent in vitro activity against…”
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Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients by Papp-Wallace, Krisztina M, Becka, Scott A, Zeiser, Elise T, Ohuchi, Nozomi, Mojica, Maria F, Gatta, Julian A, Falleni, Monica, Tosi, Delfina, Borghi, Elisa, Winkler, Marisa L, Wilson, Brigid M, LiPuma, John J, Nukaga, Michiyoshi, Bonomo, Robert A

“…Burkholderia multivorans is a significant health threat to persons with cystic fibrosis (CF). Infections are difficult to treat as this pathogen is inherently…”
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The urgent need for metallo-β-lactamase inhibitors: an unattended global threat by Mojica, Maria F, Rossi, Maria-Agustina, Vila, Alejandro J, Bonomo, Robert A

“…Due to their superior tolerability and efficacy, β-lactams are the most potent and prescribed class of antibiotics in the clinic. The emergence of resistance…”
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Carbapenem-resistant Enterobacter cloacae isolates producing KPC-3, North Dakota, USA by Kiedrowski, Lee M, Guerrero, Dubert M, Perez, Federico, Viau, Roberto A, Rojas, Laura J, Mojica, Maria F, Rudin, Susan D, Hujer, Andrea M, Marshall, Steven H, Bonomo, Robert A

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Association of COVID-19 coinfection with increased mortality among patients with Pseudomonas aeruginosa bloodstream infection in the Veterans Health Administration system by Hojat, Leila S, Wilson, Brigid M, Perez, Federico, Mojica, Maria F, Singer, Mendel E, Bonomo, Robert A, Epstein, Lauren H

“…bloodstream infection (PA-BSI) and COVID-19 are independently associated with high mortality. We sought to demonstrate the impact of COVID-19 coinfection on…”
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First Identification of OXA-72 Carbapenemase from Acinetobacter pittii in Colombia by CAMILA MONTEALEGRE, Maria, JOSE MAYA, Juan, CORREA, Adriana, ESPINAL, Paula, MOJICA, Maria F, RUIZ, Sory J, ROSSO, Fernando, VILA, Jordi, QUINN, John P, VIRGINIA VILLEGAS, Maria

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The hylEfm gene in pHylEfm of Enterococcus faecium is not required in pathogenesis of murine peritonitis by Panesso, Diana, Montealegre, Maria C, Rincón, Sandra, Mojica, Maria F, Rice, Louis B, Singh, Kavindra V, Murray, Barbara E, Arias, Cesar A

“…Plasmids containing hylEfm (pHylEfm) were previously shown to increase gastrointestinal colonization and lethality of Enterococcus faecium in experimental…”
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Treatment approaches for severe Stenotrophomonas maltophilia infections by Mojica, Maria F., Bonomo, Robert A., van Duin, David

“…Purpose of review Stenotrophomonas maltophilia is an emerged opportunistic pathogen. Intrinsic multidrug resistance makes treating infections caused by S…”
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