Search Results - "Moitra, Jaideep"

Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter by Pendyala, Srikanth, Moitra, Jaideep, Kalari, Satish, Kleeberger, Steven R., Zhao, Yutong, Reddy, Sekhar P., Garcia, Joe G.N., Natarajan, Viswanathan

“…Reactive oxygen species (ROS) generated by vascular endothelial and smooth muscle cells contribute to the development and progression of vascular diseases. We…”
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Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung by Sammani, Saad, Moreno-Vinasco, Liliana, Mirzapoiazova, Tamara, Singleton, Patrick A, Chiang, Eddie T, Evenoski, Carrie L, Wang, Ting, Mathew, Biji, Husain, Aliya, Moitra, Jaideep, Sun, Xiaoguang, Nunez, Luis, Jacobson, Jeffrey R, Dudek, Steven M, Natarajan, Viswanathan, Garcia, Joe G N

“…The therapeutic options for ameliorating the profound vascular permeability, alveolar flooding, and organ dysfunction that accompanies acute inflammatory lung…”
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Re-evaluation of Evans Blue dye as a marker of albumin clearance in murine models of acute lung injury by Moitra, Jaideep, Sammani, Saad, Garcia, Joe G.N

“…Quantifying the amount of albumin conjugated to Evans Blue dye (EBA) fluxing across organ-specific vascular barriers is a popular technique to measure…”
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Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury by Mirzapoiazova, Tamara, Moitra, Jaideep, Moreno-Vinasco, Liliana, Sammani, Saad, Turner, Jerry R, Chiang, Eddie T, Evenoski, Carrie, Wang, Ting, Singleton, Patrick A, Huang, Yong, Lussier, Yves A, Watterson, D Martin, Dudek, Steven M, Garcia, Joe G N

“…Acute lung injury (ALI) and mechanical ventilator-induced lung injury (VILI), major causes of acute respiratory failure with elevated morbidity and mortality,…”
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Essential Role of Pre-B-Cell Colony Enhancing Factor in Ventilator-induced Lung Injury by Hong, Sang-Bum, Huang, Yong, Moreno-Vinasco, Liliana, Sammani, Saad, Moitra, Jaideep, Barnard, Joseph W, Ma, Shwu-Fan, Mirzapoiazova, Tamara, Evenoski, Carrie, Reeves, Ryan R, Chiang, Eddie T, Lang, Gabriel D, Husain, Aliya N, Dudek, Steven M, Jacobson, Jeffrey R, Ye, Shui Q, Lussier, Yves A, Garcia, Joe G. N

“…We previously demonstrated pre-B-cell colony enhancing factor (PBEF) as a biomarker in sepsis and sepsis-induced acute lung injury (ALI) with genetic variants…”
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Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endothelium by Brown, Mary, Adyshev, Djanybek, Bindokas, Vytautus, Moitra, Jaideep, Garcia, Joe G.N., Dudek, Steven M.

“…Vascular barrier regulation is intimately linked to alterations in the distribution and configuration of the endothelial cell (EC) cytoskeleton in response to…”
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Life without white fat: a transgenic mouse by Moitra, J, Mason, M M, Olive, M, Krylov, D, Gavrilova, O, Marcus-Samuels, B, Feigenbaum, L, Lee, E, Aoyama, T, Eckhaus, M, Reitman, M L, Vinson, C

“…We have generated a transgenic mouse with no white fat tissue throughout life. These mice express a dominant-negative protein, termed A-ZIP/F, under the…”
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Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium by Singleton, Patrick A., Pendyala, Srikanth, Gorshkova, Irina A., Mambetsariev, Nurbek, Moitra, Jaideep, Garcia, Joe G.N., Natarajan, Viswanathan

“…Reactive oxygen species (ROS) generation, particularly by the endothelial NADPH oxidase family of proteins, plays a major role in the pathophysiology…”
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Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility by Sun, Xiaoguang, MD, PhD, Ma, Shwu-Fan, PhD, Wade, Michael S., MSc, Flores, Carlos, PhD, Pino-Yanes, Maria, MSc, Moitra, Jaideep, PhD, Ober, Carole, PhD, Kittles, Rick, PhD, Husain, Aliya N., MD, Ford, Jean G., MD, Garcia, Joe G.N., MD

“…Background The genetic mechanisms underlying asthma remain unclear. Increased permeability of the microvasculature is a feature of asthma, and the…”
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Inhibition of CREB Function in Mouse Epidermis Reduces Papilloma Formation by Rozenberg, Julian, Rishi, Vikas, Orosz, Andras, Moitra, Jaideep, Glick, Adam, Vinson, Charles

“…We used a double transgenic tetracycline system to conditionally express A-CREB, a dominant negative protein that prevents the DNA binding and function of…”
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Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations by Gao, Li, Flores, Carlos, Fan-Ma, Shwu, Miller, Edmund J, Moitra, Jaideep, Moreno, Liliana, Wadgaonkar, Raj, Simon, Brett, Brower, Roy, Sevransky, Jonathan, Tuder, Rubin M, Maloney, James P, Moss, Marc, Shanholtz, Carl, Yates, C. Ryan, Meduri, Gianfranco Umberto, Ye, Shui Q, Barnes, Kathleen C, Garcia, Joe G.N

“…The macrophage migration inhibitory factor (MIF), a pro-inflammatory cytokine central to the response to endotoxemia, is a putative biomarker in acute lung…”
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Suppression of the C/EBP family of transcription factors in adipose tissue causes lipodystrophy by Chatterjee, Raghunath, Bhattacharya, Paramita, Gavrilova, Oksana, Glass, Kimberly, Moitra, Jaideep, Myakishev, Max, Pack, Stephanie, Jou, William, Feigenbaum, Lionel, Eckhaus, Michael, Vinson, Charles

“…Adipose-specific inactivation of both AP-1 and CCAAT-enhancer-binding protein (C/EBP) families of B-ZIP transcription factors in transgenic mice causes severe…”
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Leucine Is the Most Stabilizing Aliphatic Amino Acid in the d Position of a Dimeric Leucine Zipper Coiled Coil by Moitra, Jaideep, Szilák, Lászlo, Krylov, Dmitry, Vinson, Charles

“…The energetic contribution of seven amino acids in the d position of a dimeric leucine zipper coiled coil structure was measured by determining the thermal…”
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CD44 Regulates Hepatocyte Growth Factor-mediated Vascular Integrity by Singleton, Patrick A., Salgia, Ravi, Moreno-Vinasco, Liliana, Moitra, Jaideep, Sammani, Saad, Mirzapoiazova, Tamara, Garcia, Joe G.N.

“…The preservation of vascular endothelial cell (EC) barrier integrity is critical to normal vessel homeostasis, with barrier dysfunction being a feature of…”
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Transgenic Mice Lacking White Fat: Models for Understanding Human Lipoatrophic Diabetes by REITMAN, MARC L., MASON, MARK M., MOITRA, JAIDEEP, GAVRILOVA, OKSANA, MARCUS-SAMUELS, BERNICE, ECKHAUS, MICHAEL, VINSON, CHARLES

“…The human disease lipoatrophic (or lipodystrophic) diabetes is a rare syndrome in which a deficiency of adipose tissue is associated with Type 2 diabetes. This…”
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Abstract 461: Antiphospholipid Antibodies In Covid-19 Convalescent Plasma by Becicka, Wyatt, Berreby, Gil, Wang, Jintao, Moitra, Jaideep, Panicker, Sumith, Tourdot, Benjamin, Norris, Philip, Kelly, Kathleen, Zouo, Yu, Dumont, Larry, Knight, Jason, Kanthi, Yogendra

“…BackgroundAlthough convalescent plasma has historically yielded significant benefits in the treatment of infectious diseases, numerous clinical trials have not…”
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Abstract 123: Genetic Deficiency Of The Ectoenzyme CD73 Increases Neutrophil Extracellular Trap Formation In Patients With ACDC by Becicka, Wyatt, Garrad, Evan, Berreby, Gil, Wang, Jintao, Nghiem, Khanh, Ramos-Benitez, Marcos, Cowling, Bretagne, Moitra, Jaideep, Huffstutler, Rebecca, Carney, Katherine, Ferrante, Elisa, Cudrici, Cornelia, Brofferio, Alessandra, Tourdot, Benjamin, Jacobson, Kenneth, Knight, Jason, Kanthi, Yogendra, Boehm, Manfred

“…Background/PurposeCD73 is a ecto-5′-nucleotidase located on the plasma membrane that generates adenosine from AMP in the extracellular space, and functions as…”
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Identification of a Nuclear Factor-I Family Protein-binding Site in the Silencer Region of the Cartilage Matrix Protein Gene by Szabó, P, Moitra, J, Rencendorj, A, Rákhely, G, Rauch, T, Kiss, I

“…Cartilage matrix protein (CMP) is synthesized by chondrocytes in a developmentally regulated manner. Here we have dissected promoter upstream elements involved…”
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CD44 Regulates Hepatocyte Growth Factor-mediated Vascular Integrity: ROLE OF c-Met, Tiam1/Rac1, DYNAMIN 2, AND CORTACTIN by Singleton, Patrick A, Salgia, Ravi, Moreno-Vinasco, Liliana, Moitra, Jaideep, Sammani, Saad, Mirzapoiazova, Tamara, Garcia, Joe G.N

“…The preservation of vascular endothelial cell (EC) barrier integrity is critical to normal vessel homeostasis, with barrier dysfunction being a feature of…”
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Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome by Sun, Xiaoguang, Ma, Shwu-Fan, Wade, Michael S, Acosta-Herrera, Marialbert, Villar, Jesús, Pino-Yanes, Maria, Zhou, Tong, Liu, Bin, Belvitch, Patrick, Moitra, Jaideep, Han, Yoo-Jeong, Machado, Roberto, Noth, Imre, Natarajan, Viswanathan, Dudek, Steven M, Jacobson, Jeffrey R, Flores, Carlos, Garcia, Joe G N

“…The genetic mechanisms underlying the susceptibility to acute respiratory distress syndrome (ARDS) are poorly understood. We previously demonstrated that…”
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