Search Results - "Moita, Luis Ferreira"

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues by Poulin, Lionel F., Reyal, Yasmin, Uronen-Hansson, Heli, Schraml, Barbara U., Sancho, David, Murphy, Kenneth M., Håkansson, Ulf K., Ferreira Moita, Luis, Agace, William W., Bonnet, Dominique, Reis e Sousa, Caetano

“…Mouse CD8α+ dendritic cells (DCs) in lymphoid organs and CD103+ CD11b− DCs in nonlymphoid tissues share phenotypic and functional similarities, as well as a…”
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Potential benefit of angiotensin II in COVID-19 patients: beyond reasonable doubt? by Tralhão, António, Moita, Luís Ferreira, Póvoa, Pedro

“…Cognizant of the dilemma of having to manage critically ill patients in the absence of disease-specific data, we must continue to rely on tangentially-related,…”
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Regulation of CD45 Alternative Splicing by Heterogeneous Ribonucleoprotein, hnRNPLL by Oberdoerffer, Shalini, Moita, Luis Ferreira, Neems, Daniel, Freitas, Rui P, Hacohen, Nir, Rao, Anjana

“…The transition from naïve to activated T cells is marked by alternative splicing of pre-mRNA encoding the transmembrane phosphatase CD45. Using a short hairpin…”
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Potent Anti-Inflammatory and Antiproliferative Effects of Gambogic Acid in a Rat Model of Antigen-Induced Arthritis by Ferreira Moita, Luis, Gupta, Vineet, Figueiredo, Nuno, Neves-Costa, Ana, Raquel, Helena, Vidal, Bruno, Cascão, R., Fonseca, Joao Eurico

“…Background. We have previously reported a continuous activation of caspase-1 and increased interleukin (IL)-1β levels in early rheumatoid arthritis (RA). These…”
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Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection by Robinson, Matthew J, Osorio, Fabiola, Rosas, Marcela, Freitas, Rui P, Schweighoffer, Edina, Gross, Olaf, Verbeek, J Sjef, Ruland, Jürgen, Tybulewicz, Victor, Brown, Gordon D, Moita, Luis Ferreira, Taylor, Philip R, Reis e Sousa, Caetano

“…Innate immune cells detect pathogens via pattern recognition receptors (PRRs), which signal for initiation of immune responses to infection. Studies with…”
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shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity by Gonçalves, Susana A, Macedo, Diana, Raquel, Helena, Simões, Pedro D, Giorgini, Flaviano, Ramalho, José S, Barral, Duarte C, Ferreira Moita, Luís, Outeiro, Tiago Fleming

“…Alpha-Synuclein (aSyn) misfolding and aggregation is common in several neurodegenerative diseases, including Parkinson's disease and dementia with Lewy bodies,…”
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Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells by Gonçalves, Vânia, Henriques, Andreia F A, Henriques, Andreia, Pereira, Joana F S, Pereira, Joana, Neves Costa, Ana, Moyer, Mary Pat, Moita, Luís Ferreira, Gama-Carvalho, Margarida, Matos, Paulo, Jordan, Peter

“…The premessenger RNA of the majority of human genes can generate various transcripts through alternative splicing, and different tissues or disease states show…”
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Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate by Gerber, Pehuén Pereyra, Cabrini, Mercedes, Jancic, Carolina, Paoletti, Luciana, Banchio, Claudia, von Bilderling, Catalina, Sigaut, Lorena, Pietrasanta, Lía I, Duette, Gabriel, Freed, Eric O, Basile, Genevieve de Saint, Moita, Catarina Ferreira, Moita, Luis Ferreira, Amigorena, Sebastian, Benaroch, Philippe, Geffner, Jorge, Ostrowski, Matías

“…During the late stages of the HIV-1 replication cycle, the viral polyprotein Pr55(Gag) is recruited to the plasma membrane (PM), where it binds…”
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Zinc inhibits lethal inflammatory shock by preventing microbe‐induced interferon signature in intestinal epithelium by Souffriau, Jolien, Timmermans, Steven, Vanderhaeghen, Tineke, Wallaeys, Charlotte, Van Looveren, Kelly, Aelbrecht, Lindsy, Dewaele, Sylviane, Vandewalle, Jolien, Goossens, Evy, Verbanck, Serge, Boyen, Filip, Eggermont, Melanie, De Commer, Lindsey, De Rycke, Riet, De Bruyne, Michiel, Tito, Raul, Ballegeer, Marlies, Vandevyver, Sofie, Velho, Tiago, Moita, Luis Ferreira, Hochepied, Tino, De Bosscher, Karolien, Raes, Jeroen, Van Immerseel, Filip, Beyaert, Rudi, Libert, Claude

“…The cytokine TNF drives inflammatory diseases, e.g., Crohn's disease. In a mouse model of TNF‐induced systemic inflammatory response syndrome (SIRS), severe…”
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The impact of cardiopulmonary bypass time on the Sequential Organ Failure Assessment score after cardiac surgery by Velho, Tiago R, Pereira, Rafael Maniés, Guerra, Nuno Carvalho, Ferreira, Ricardo, Pedroso, Dora, Neves-Costa, Ana, Nobre, Ângelo, Moita, Luís Ferreira

“…Postoperative organ dysfunction is common after cardiac surgery, particularly when cardiopulmonary bypass (CPB) is used. The Sequential Organ Failure…”
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Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial by Thomas-Rüddel, Daniel, Bauer, Michael, Moita, Luís Ferreira, Helbig, Christiane, Schlattmann, Peter, Ehler, Johannes, Rahmel, Tim, Meybohm, Patrick, Gründling, Matthias, Schenk, Heiko, Köcher, Thomas, Brunkhorst, Frank M, Gräler, Markus, Heger, Ann-Julika, Weis, Sebastian, Bloos, Frank, Dlubatz, Karen, Hagel, Stefan, Hammersen, Jakob, Lehmann, Thomas, Leonhardt, Katja, Markgraf, René, Michael, Matthias, Rißner, Florian, Röstel, Franziska, Roth, Johannes, Schumacher, Ulrike, Schwarze, Nicole, Städtler, Mariann, Vivas-Varela, Wolfgang, Fuchs, Christian, Greinacher, Andreas, Kuhn, Sven-Olaf, Hagedorn, Andre, Unterberg, Matthias, Wittkowski, Andrea, Rumpf, Florian, Haas, Tobias, Helmer, Philipp, Hottenrott, Sebastian, Kranke, Eva, Kranke, Peter, Neuf, Marianne, Reppchen, Anke, Röder, Daniel, Schmidt, Julius

“…IntroductionSepsis remains the major cause of death among hospitalised patients in intensive care. While targeting sepsis-causing pathogens with source control…”
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Decrease of perforin positive CD3+γδ-T cells in patients with obstructive sleep disordered breathing by Staats, Richard, Rodrigues, Raquel, Barros, André, Bacelar-Nicolau, Leonor, Aguiar, Margarida, Fernandes, Dina, Moreira, Susana, Simões, André, Silva-Santos, Bruno, Rodrigues, João Valença, Barbara, Cristina, de Almeida, António Bugalho, Moita, Luis Ferreira

“…Introduction Sleep related breathing disorders (SRBD) cause sleep fragmentation, intermittent hypoxia or a combination of both leading to homeostasis…”
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Role of CD3+γδ-T cells in the association of obstructive sleep-disordered breathing and cancer by Staats, Richard, Rodrigues, Raquel, Barros, André, Bacelar-Nicolau, Leonor, Aguiar, Margarida, Fernandes, Dina, Moreira, Susana, Simões, André, Silva-Santos, Bruno, Rodrigues, João Valença, Barbara, Cristina, de Almeida, António Bugalho, Ferreira Moita, Luís F.

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Celastrol efficacy by oral administration in the adjuvant-induced arthritis model by Cascão, Rita, Costa Vidal, Bruno Miguel, Carvalho, Tânia, Lopes, Inês, C Romão, Vasco, Goncalves, Joao, Moita, Luis, Fonseca, João

“…Copyright © 2020 Cascão, Vidal, Carvalho, Lopes, Romão, Goncalves, Moita and Fonseca. This is an open-access article distributed under the terms of the…”
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Sequential Organ Failure Assessment Score in the ICU As a Predictor of Long-Term Survival After Cardiac Surgery by Velho, Tiago R, Pereira, Rafael Maniés, Paixão, Tiago, Guerra, Nuno Carvalho, Ferreira, Ricardo, Corte-Real, Hugo, Nobre, Ângelo, Moita, Luís Ferreira

“…The Sequential Organ Failure Assessment (SOFA) score is a predictor of mortality in ICU patients. Although it is widely used and has been validated as a…”
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Sepsis: the need for tolerance not complacency by Velho, Tiago R, Santos, Isa, Póvoa, Pedro, Moita, Luís Ferreira

“…Sepsis is a life-threatening condition that arises as a systemic inflammatory response syndrome to an infection. Its uncontrolled progression can in frequent…”
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Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells by Rato, Sylvie, Maia, Sara, Brito, Paula M, Resende, Leonor, Pereira, Carina F, Moita, Catarina, Freitas, Rui P, Moniz-Pereira, José, Hacohen, Nir, Moita, Luis Ferreira, Goncalves, Joao

“…HIV-1 is a complex retrovirus that uses host machinery to promote its replication. Understanding cellular proteins involved in the multistep process of HIV-1…”
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Changes in Expression of the CLOCK Gene in Obstructive Sleep Apnea Syndrome Patients Are Not Reverted by Continuous Positive Airway Pressure Treatment by Moreira, Susana, Rodrigues, Raquel, Barros, André B, Pejanovic, Nadja, Neves-Costa, Ana, Pedroso, Dora, Pereira, Cláudia, Fernandes, Dina, Rodrigues, João Valença, Barbara, Cristina, Moita, Luís Ferreira

“…Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal…”
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Role of omega-6 fatty acid metabolism in cardiac surgery postoperative bleeding risk by Velho, Tiago, Ferreira, Ricardo, Willmann, Katharina, Pedroso, Dora, Paixão, Tiago, Pereira, Rafael Maniés, Junqueira, Nádia, Carvalho Guerra, Nuno, Brito, Dulce, Almeida, Ana, Lucas Pereira Nobre, Angelo Manuel, Köcher, Thomas, Pinto, Fausto J., Moita, Luís Ferreira

“…Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine. This is an open-access article…”
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Activated clotting time value as an independent predictor of postoperative bleeding and transfusion by Pereira, Rafael Maniés, Magueijo, Diogo, Guerra, Nuno Carvalho, Correia, Catarina Jacinto, Rodrigues, Anabela, Nobre, Ângelo, Brito, Dulce, Moita, Luís Ferreira, Velho, Tiago R

“…Activated clotting time (ACT) is commonly used to monitor anticoagulation during cardiac surgeries. Final ACT values may be essential to predict postoperative…”
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