Search Results - "Moin, Abu Saleh Md"
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One-day high-fat diet induces inflammation in the nodose ganglion and hypothalamus of mice
Published in Biochemical and biophysical research communications (04-09-2015)“…A high-fat diet (HFD) induces inflammation in systemic organs including the hypothalamus, resulting in obesity and diabetes. The vagus nerve connects the…”
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2
Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation
Published in Journal of endocrinology (01-07-2015)“…Ghrelin, a stomach-derived orexigenic peptide, transmits starvation signals to the hypothalamus via the vagus afferent nerve. Peripheral administration of…”
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3
Increased Frequency of Hormone Negative and Polyhormonal Endocrine Cells in Lean Individuals With Type 2 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-10-2016)“…Context: It has been suggested that beta cell loss in type 2 diabetes (T2D) may be due to beta cell degranulation and/or altered cell identity. While shown to…”
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Increased Hormone-Negative Endocrine Cells in the Pancreas in Type 1 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-09-2016)“…Context and Objective: Type 1 diabetes (T1D) is characterized by a β-cell deficit due to autoimmune inflammatory-mediated β-cell destruction. It has been…”
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Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-01-2017)“…Context: Pancreatic duct glands (PDGs) have been proposed as a source of regeneration in response to exocrine pancreas injury, and thus may serve as an organ…”
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Increased Chromogranin A–Positive Hormone-Negative Cells in Chronic Pancreatitis
Published in The journal of clinical endocrinology and metabolism (01-06-2018)“…Abstract Context Chronic pancreatitis (CP) is characterized by inflammation, fibrosis, and a loss of pancreatic acinar cells, which can result in exocrine and…”
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Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
Published in Current diabetes reports (01-09-2019)“…Purpose of Review To discuss the current understanding of “β cell identity” and factors underlying altered identity of pancreatic β cells in diabetes,…”
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8
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published in Frontiers in endocrinology (Lausanne) (09-01-2019)“…Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing…”
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9
Coagulation factor dysregulation in polycystic ovary syndrome is an epiphenomenon of obesity
Published in Clinical endocrinology (Oxford) (01-06-2023)“…Objective Obese women with polycystic ovary syndrome (PCOS) exhibit a hypercoagulable state, with the suggestion that this may be obesity‐driven rather than an…”
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10
Environmental Pollution and the Risk of Developing Metabolic Disorders: Obesity and Diabetes
Published in International journal of molecular sciences (17-05-2023)“…To meet the increased need for food and energy because of the economic shift brought about by the Industrial Revolution in the 19th century, there has been an…”
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11
A Cross-Sectional Study of Alzheimer-Related Proteins in Women with Polycystic Ovary Syndrome
Published in International journal of molecular sciences (01-01-2024)“…Polycystic ovary syndrome (PCOS) is the most common endocrine condition in women of reproductive age, and several risk factors found in PCOS are associated…”
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The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature
Published in International journal of molecular sciences (17-01-2023)“…Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and post-menopausal women. PCOS is a multifactorial…”
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Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19
Published in Scientific reports (19-03-2021)“…Hyperactivation of the immune system through obesity and diabetes may enhance infection severity complicated by Acute Respiratory Distress Syndrome (ARDS). The…”
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A Cross-Sectional Study of Protein Changes Associated with Dementia in Non-Obese Weight Matched Women with and without Polycystic Ovary Syndrome
Published in International journal of molecular sciences (01-02-2024)“…Dysregulated Alzheimer's disease (AD)-associated protein expression is reported in polycystic ovary syndrome (PCOS), paralleling the expression reported in…”
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15
Hypoglycaemia in type 2 diabetes exacerbates amyloid‐related proteins associated with dementia
Published in Diabetes, obesity & metabolism (01-02-2021)“…Aims Hypoglycaemia in diabetes (T2D) may increase the risk of Alzheimer's disease (AD). We hypothesized that hypoglycaemia‐induced amyloid‐related protein…”
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16
Glycemia-Induced miRNA Changes: A Review
Published in International journal of molecular sciences (01-04-2023)“…Diabetes is a rapidly increasing global health concern that significantly strains the health system due to its downstream complications. Dysregulation in…”
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Components of the Complement Cascade Differ in Polycystic Ovary Syndrome
Published in International journal of molecular sciences (13-10-2022)“…Complement pathway proteins are reported to be increased in polycystic ovary syndrome (PCOS) and may be affected by obesity and insulin resistance. To…”
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Therapeutic Applications of Stem Cell-Derived Exosomes
Published in International journal of molecular sciences (01-03-2024)“…Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in diameter, that mediate intercellular transfer of various biomolecules,…”
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Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response
Published in Diabetes, obesity & metabolism (01-08-2022)“…Introduction There is evidence that fibroblast growth factor (FGF) levels may be implicated in hypoglycaemia, with FGF19 being a potential contributor to…”
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Dementia in Diabetes: The Role of Hypoglycemia
Published in International journal of molecular sciences (01-06-2023)“…Hypoglycemia, a common consequence of diabetes treatment, is associated with severe morbidity and mortality and has become a major barrier to intensifying…”
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