Search Results - "Moin, A"

Molecular stratification of idiopathic nephrotic syndrome by Saleem, Moin A.

“…Idiopathic nephrotic syndrome (INS) describes a group of pathologies of the renal glomerulus that result in the classic triad of heavy proteinuria, oedema and…”
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Gene Therapy for Glomerular Disease by Saleem, Moin A

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Long-Term Outcomes in IgA Nephropathy by Pitcher, David, Braddon, Fiona, Hendry, Bruce, Mercer, Alex, Osmaston, Kate, Saleem, Moin A, Steenkamp, Retha, Wong, Katie, Turner, A Neil, Wang, Kaijun, Gale, Daniel P, Barratt, Jonathan

“…IgA nephropathy can progress to kidney failure, and risk assessment soon after diagnosis has advantages both for clinical management and the development of new…”
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What is circulating factor disease and how is it currently explained? by Hayward, Samantha, Parmesar, Kevon, Saleem, Moin A.

“…Nephrotic syndrome (NS) consists of the clinical triad of hypoalbuminaemia, high levels of proteinuria and oedema, and describes a heterogeneous group of…”
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β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes by Audzeyenka, Irena, Szrejder, Maria, Rogacka, Dorota, Angielski, Stefan, Saleem, Moin A., Piwkowska, Agnieszka

“…Podocytes constitute an external layer of the glomerular filtration barrier, injury to which is a hallmark of renal disease. Mitochondrial dysfunction often…”
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One hundred ways to kill a podocyte by Saleem, Moin A

“…The podocyte is a highly specialized cell, forming within the developing glomerulus from a mesenchymal origin, acquiring some but not complete features of an…”
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What is the Role of Soluble Urokinase-Type Plasminogen Activator in Renal Disease? by Saleem, Moin A

“…Soluble urokinase-type plasminogen activator -(suPAR) is an inflammatory signal with pleiotropic biological effects depending on context and post-translational…”
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Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice by Beckerman, Pazit, Bi-Karchin, Jing, Park, Ae Seo Deok, Qiu, Chengxiang, Dummer, Patrick D, Soomro, Irfana, Boustany-Kari, Carine M, Pullen, Steven S, Miner, Jeffrey H, Hu, Chien-An A, Rohacs, Tibor, Inoue, Kazunori, Ishibe, Shuta, Saleem, Moin A, Palmer, Matthew B, Cuervo, Ana Maria, Kopp, Jeffrey B, Susztak, Katalin

“…Risk variants of APOL1 associated with human chronic kidney disease have been identified, but causality has been unclear. Transgenic expression in mice now…”
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Deriving and understanding the risk of post-transplant recurrence of nephrotic syndrome in the light of current molecular and genetic advances by Bierzynska, Agnieszka, Saleem, Moin A.

“…After renal transplantation, recurrence of the original disease is the second most common cause of graft loss, after rejection. The most dramatic manifestation…”
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Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management by Bierzynska, Agnieszka, McCarthy, Hugh J, Soderquest, Katrina, Sen, Ethan S, Colby, Elizabeth, Ding, Wen Y, Nabhan, Marwa M, Kerecuk, Larissa, Hegde, Shivram, Hughes, David, Marks, Stephen, Feather, Sally, Jones, Caroline, Webb, Nicholas J A, Ognjanovic, Milos, Christian, Martin, Gilbert, Rodney D, Sinha, Manish D, Lord, Graham M, Simpson, Michael, Koziell, Ania B, Welsh, Gavin I, Saleem, Moin A

“…Steroid Resistant Nephrotic Syndrome (SRNS) in children and young adults has differing etiologies with monogenic disease accounting for 2.9-30% in selected…”
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Insulin induces bioenergetic changes and alters mitochondrial dynamics in podocytes by Audzeyenka, Irena, Rachubik, Patrycja, Rogacka, Dorota, Saleem, Moin A, Piwkowska, Agnieszka

“…Diabetic nephropathy (DN) is one of the most frequent complications of diabetes. Early stages of DN are associated with hyperinsulinemia and progressive…”
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G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes by Wang, Xiaoxin X, Edelstein, Michal Herman, Gafter, Uzi, Qiu, Liru, Luo, Yuhuan, Dobrinskikh, Evgenia, Lucia, Scott, Adorini, Luciano, D'Agati, Vivette D, Levi, Jonathan, Rosenberg, Avi, Kopp, Jeffrey B, Gius, David R, Saleem, Moin A, Levi, Moshe

“…Obesity and diabetes mellitus are the leading causes of renal disease. In this study, we determined the regulation and role of the G protein-coupled bile acid…”
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TRPC6 Binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility by Farmer, Louise K, Rollason, Ruth, Whitcomb, Daniel J, Ni, Lan, Goodliff, Alexander, Lay, Abigail C, Birnbaumer, Lutz, Heesom, Kate J, Xu, Shang-Zhong, Saleem, Moin A, Welsh, Gavin I

“…Mutations in the transient receptor potential channel 6 ( ) gene are associated with an inherited form of FSGS. Despite widespread expression, patients with…”
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The podocyte cytoskeleton—key to a functioning glomerulus in health and disease by Welsh, Gavin I., Saleem, Moin A.

“…An understanding of the intricacies of cytoskeletal dynamics and regulation in podocytes is essential to facilitate investigation and treatment of patients…”
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IPNA clinical practice recommendations for the diagnosis and management of children with steroid-resistant nephrotic syndrome by Trautmann, Agnes, Vivarelli, Marina, Samuel, Susan, Gipson, Debbie, Sinha, Aditi, Schaefer, Franz, Hui, Ng Kar, Boyer, Olivia, Saleem, Moin A, Feltran, Luciana, Müller-Deile, Janina, Becker, Jan Ulrich, Cano, Francisco, Xu, Hong, Lim, Yam Ngo, Smoyer, William, Anochie, Ifeoma, Nakanishi, Koichi, Hodson, Elisabeth, Haffner, Dieter

“…Idiopathic nephrotic syndrome newly affects 1–3 per 100,000 children per year. Approximately 85% of cases show complete remission of proteinuria following…”
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Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome by Ebarasi, Lwaki, Ashraf, Shazia, Bierzynska, Agnieszka, Gee, Heon Yung, McCarthy, Hugh J., Lovric, Svjetlana, Sadowski, Carolin E., Pabst, Werner, Vega-Warner, Virginia, Fang, Humphrey, Koziell, Ania, Simpson, Michael A., Dursun, Ismail, Serdaroglu, Erkin, Levy, Shawn, Saleem, Moin A., Hildebrandt, Friedhelm, Majumdar, Arindam

“…Nephrotic syndrome (NS), the association of gross proteinuria, hypoalbuminaemia, edema, and hyperlipidemia, can be clinically divided into steroid-sensitive…”
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New developments in steroid-resistant nephrotic syndrome by Saleem, Moin A.

“…Nephrotic syndrome is a disorder of the glomerular filtration barrier, a highly specialised tri-layer structure with unique functional properties. Recent…”
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Low frequency view of GRB 190114C reveals time varying shock micro-physics by Misra, K, Resmi, L, Kann, D A, Marongiu, M, Moin, A, Klose, S, Bernardi, G, de Ugarte Postigo, A, Jaiswal, V K, Schulze, S, Perley, D A, Ghosh, A, Kumar, H, Gupta, R, Michałowski, M J, Martín, S, Cockeram, A, Cherukuri, S V, Bhalerao, V, Anderson, G E, Pandey, S B, Anupama, G C, Thöne, C C, Barway, S, Wieringa, M H, Fynbo, J P U, Habeeb, N

“…ABSTRACT We present radio and optical afterglow observations of the TeV-bright long gamma-ray burst 190114C at a redshift of z = 0.425, which was detected by…”
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Nephrin--signature molecule of the glomerular podocyte by Welsh, Gavin I, Saleem, Moin A

“…In recent years there has been an explosion of interest in the glomerular podocyte, which plays a central role in control of glomerular filtration. A host of…”
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Dysregulated autophagy contributes to podocyte damage in Fabry's disease by Liebau, Max C, Braun, Fabian, Höpker, Katja, Weitbrecht, Claudia, Bartels, Valerie, Müller, Roman-Ulrich, Brodesser, Susanne, Saleem, Moin A, Benzing, Thomas, Schermer, Bernhard, Cybulla, Markus, Kurschat, Christine E

“…Fabry's disease results from an inborn error of glycosphingolipid metabolism that is due to deficiency of the lysosomal hydrolase α-galactosidase A. This…”
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