Search Results - "Moi, David"
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OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more
Published in Nucleic acids research (08-01-2021)“…Abstract OMA is an established resource to elucidate evolutionary relationships among genes from currently 2326 genomes covering all domains of life. OMA…”
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A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor
Published in eLife (04-12-2020)“…The insect chemosensory repertoires of Odorant Receptors (ORs) and Gustatory Receptors (GRs) together represent one of the largest families of ligand-gated ion…”
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Scalable phylogenetic profiling using MinHash uncovers likely eukaryotic sexual reproduction genes
Published in PLoS computational biology (22-07-2020)“…Phylogenetic profiling is a computational method to predict genes involved in the same biological process by identifying protein families which tend to be…”
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Arabidopsis HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens
Published in The Journal of cell biology (06-03-2017)“…Cell-cell fusion is inherent to sexual reproduction. Loss of HAPLESS 2/GENERATIVE CELL SPECIFIC 1 (HAP2/GCS1) proteins results in gamete fusion failure in…”
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Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
Published in Nature communications (06-07-2022)“…Sexual reproduction consists of genome reduction by meiosis and subsequent gamete fusion. The presence of genes homologous to eukaryotic meiotic genes in…”
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Phylogenetic profiling in eukaryotes comes of age
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2023)Get full text
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7
Frequent jumps from human hosts
Published in Nature ecology & evolution (01-05-2024)“…An analysis of publicly available viral genomes explores the evolutionary dynamics of host jumps and shows that humans are as much a source of viral spillover…”
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Remote homolog detection places insect chemoreceptors in a cryptic protein superfamily spanning the tree of life
Published in Current biology (20-11-2023)“…Many proteins exist in the so-called "twilight zone" of sequence alignment, where low pairwise sequence identity makes it difficult to determine homology and…”
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OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem
Published in Nucleic acids research (05-01-2024)“…Abstract In this update paper, we present the latest developments in the OMA browser knowledgebase, which aims to provide high-quality orthology inferences and…”
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Citrullination Was Introduced into Animals by Horizontal Gene Transfer from Cyanobacteria
Published in Molecular biology and evolution (03-02-2022)“…Abstract Protein posttranslational modifications add great sophistication to biological systems. Citrullination, a key regulatory mechanism in human physiology…”
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Gene Duplication and Gain in the Trematode Atriophallophorus winterbourni Contributes to Adaptation to Parasitism
Published in Genome biology and evolution (01-03-2021)“…Abstract Gene duplications and novel genes have been shown to play a major role in helminth adaptation to a parasitic lifestyle because they provide the…”
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Ten Years of Collaborative Progress in the Quest for Orthologs
Published in Molecular biology and evolution (02-04-2021)“…Abstract Accurate determination of the evolutionary relationships between genes is a foundational challenge in biology. Homology—evolutionary relatedness—is in…”
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Journal Article Conference Proceeding -
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Britain To Continue Restricting Liquids Allowed On Planes: Brooks Bros. Fetes Scent
Published in WWD (10-09-2008)“…LONDON — The British government said this week it will continue to impose restrictions on liquids allowed in airplane hand baggage as the terrorist threat…”
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