Search Results - "Mohty, Bilal"
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Impact of gene mutations on treatment response and prognosis of acute myeloid leukemia secondary to myeloproliferative neoplasms
Published in American journal of hematology (01-03-2018)“…Acute myeloid leukemias secondary (sAML) to myeloproliferative neoplasms (MPN) have variable clinical courses and outcomes, but remain almost always fatal…”
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Peripheral neuropathy and new treatments for multiple myeloma: background and practical recommendations
Published in Haematologica (Roma) (01-02-2010)“…In multiple myeloma, peripheral neuropathy has for a long time been considered as mainly secondary to the plasma cell dyscrasia itself. With the advent of new…”
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Outcome of pandemic H1N1 infections in hematopoietic stem cell transplant recipients
Published in Haematologica (Roma) (01-08-2011)“…During 2009, a new strain of A/H1N1 influenza appeared and became pandemic. A prospective study was performed to collect data regarding risk factors and…”
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Treatment of post transplant relapse of FLT3-ITD mutated AML using 5-azacytidine and sorafenib bitherapy
Published in Clinical lymphoma, myeloma and leukemia (01-04-2017)Get full text
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Graft-versus-host disease is the major determinant of humoral responses to the AS03-adjuvanted influenza A/09/H1N1 vaccine in allogeneic hematopoietic stem cell transplant recipients
Published in Haematologica (Roma) (01-06-2011)“…Responses to influenza vaccines are poorly characterized in immunocompromised patients. The goal of this study was to assess the efficacy of the…”
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Tandem autologous-allogeneic stem cell transplantation as a feasible and effective procedure in high-risk lymphoma patients
Published in Haematologica (Roma) (01-10-2015)Get full text
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Antithymocyte Globulin in Reduced-Intensity Conditioning Regimen Allows a High Disease-Free Survival Exempt of Long-Term Chronic Graft-versus-Host Disease
Published in Biology of blood and marrow transplantation (01-03-2014)“…Abstract Nonmyeloablative (NMA) regimens allow the use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients considered unfit for…”
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The effects of bortezomib on bone disease in patients with multiple myeloma
Published in Cancer (01-03-2014)“…Bortezomib has demonstrated substantial activity in the treatment of patients with multiple myeloma and is widely incorporated into treatment strategies across…”
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Long Term Analysis of a Monocentric Cohort of Therapy-Related Acute Lymphoblastic Leukemia
Published in Blood (05-11-2020)“…Therapy related Acute Lymphoblastic Leukemia (t-ALL) refers to ALL developed in patients who have received prior cytotoxic therapies, including chemotherapies…”
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Clinical, Cytogenetic and Molecular Characterization of a 96 MDS and AML Cohort with TP53 Mutation
Published in Blood (02-11-2023)“…Introduction The last European LeukamiaNet (ELN) recommendations (Döhner H. et al. Blood. 2022) and the International Consensus Classification (ICC, Hasserjian…”
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Poor Prognosis of SRSF2 Gene Mutations in Patients Treated with Venetoclax-Azacitidine (VEN-AZA) for Newly Diagnosed Acute Myeloid Leukemia. a Multicentric Real-Life Study of 117 Patients
Published in Blood (02-11-2023)“…Introduction Spliceosomes are complexes composed of small nuclear RNA that remove introns in protein-encoding genes. Spliceosome mutations ( SRSF2, SF3B1,…”
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Poor prognosis of SRSF2 gene mutations in patients treated with VEN-AZA for newly diagnosed acute myeloid leukemia
Published in Leukemia research (01-06-2024)“…Mutations in spliceosome genes (SRSF2, SF3B1, U2AF1, ZRSR2) correlate with inferior outcomes in patients treated with intensive chemotherapy for Acute Myeloid…”
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Azacitidine Plus Venetoclax for the Treatment of Relapsed and Newly Diagnosed Acute Myeloid Leukemia Patients
Published in Cancers (16-04-2022)“…Venetoclax (VEN) belongs the BH3-mimetic class that selectively targets BCL-2, activating apoptosis. The combination of VEN and azacitidine (AZA) has changed…”
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Venetoclax‐based non‐intensive induction followed by allogenic stem‐cell transplantation in elderly acute myeloid leukemia patients with adverse cytogenetics
Published in European journal of haematology (01-12-2024)“…Introduction Elderly acute myeloid leukemia (AML) patients with poor‐risk cytogenetics have a poor outcome with intensive chemotherapy (IC). While Venetoclax…”
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Unrelated cord blood compared with haploidentical grafts in patients with hematological malignancies
Published in Cancer (01-06-2015)“…BACKGROUND Alternative donors, such as unrelated umbilical cord blood (UCB) and related haploidentical (haplo) donors, are more and more frequently searched…”
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Cegal Protocol : Evaluation of the Feasibility of a Chemogenomic Approach to Identify Personalized Therapy for Relapse or Refractory AML Patients
Published in Blood (29-11-2018)“…Introduction : Significant improvements of leukemia free survival have been obtained over the last 30 years in AML. This progress has resulted from…”
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Allogeneic Hematopoietic Stem Cell Transplantation Improves Outcome of Patients > 60 Years with Acute Myeloid Leukemia in First Complete Remission: A 10-Year Single Center Transplantation Program Analysis
Published in Blood (08-12-2017)“…Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a curative option for patients with AML in first complete remission (CR1), but is limited by…”
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Allogeneic Hematopoietic Stem Cell Transplantation for Patients over 60 Years with Acute Myeloid Leukemia: A Single Center Donor Comparison
Published in Blood (08-12-2017)“…Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a curative option for patients with AML. However, most of them are diagnosed over 60 years of…”
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The Role of Donor CMV Serostatus on Outcome after T-Cell Replete Haplo-SCT and Post-Transplant Cyclophosphamide: A Cohort Analysis on 207 Consecutive Adult Patients
Published in Blood (03-12-2015)“…INTRODUCTION. In the setting of T-cell replete haploidentical transplantation, the question about the best stem cell donor is still open. Cytomegalovirus (CMV)…”
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