Search Results - "Mohr, Hermine"

Simultaneous magnetic resonance imaging of pH, perfusion and renal filtration using hyperpolarized 13C-labelled Z-OMPD by Grashei, Martin, Wodtke, Pascal, Skinner, Jason G., Sühnel, Sandra, Setzer, Nadine, Metzler, Thomas, Gulde, Sebastian, Park, Mihyun, Witt, Daniela, Mohr, Hermine, Hundshammer, Christian, Strittmatter, Nicole, Pellegata, Natalia S., Steiger, Katja, Schilling, Franz

“…pH alterations are a hallmark of many pathologies including cancer and kidney disease. Here, we introduce [1,5- 13 C 2 ]Z-OMPD as a hyperpolarized…”
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Imaging pheochromocytoma in small animals: preclinical models to improve diagnosis and treatment by Mohr, Hermine, Foscarini, Alessia, Steiger, Katja, Ballke, Simone, Rischpler, Christoph, Schilling, Franz, Pellegata, Natalia S.

“…Pheochromocytomas (PCCs) and paragangliomas (PGLs), together referred to as PPGLs, are rare chromaffin cell-derived tumors. They require timely diagnosis as…”
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Angpt2/Tie2 autostimulatory loop controls tumorigenesis by Karabid, Ninelia Minaskan, Wiedemann, Tobias, Gulde, Sebastian, Mohr, Hermine, Segaran, Renu Chandra, Geppert, Julia, Rohm, Maria, Vitale, Giovanni, Gaudenzi, Germano, Dicitore, Alessandra, Ankerst, Donna Pauler, Chen, Yiyao, Braren, Rickmer, Kaissis, Georg, Schilling, Franz, Schillmaier, Mathias, Eisenhofer, Graeme, Herzig, Stephan, Roncaroli, Federico, Honegger, Jürgen B, Pellegata, Natalia S

“…Invasive nonfunctioning (NF) pituitary neuroendocrine tumors (PitNETs) are non‐resectable neoplasms associated with frequent relapses and significant…”
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Cytomegalovirus downregulates IRE1 to repress the unfolded protein response by Stahl, Sebastian, Burkhart, Julia M, Hinte, Florian, Tirosh, Boaz, Mohr, Hermine, Zahedi, René P, Sickmann, Albert, Ruzsics, Zsolt, Budt, Matthias, Brune, Wolfram

“…During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an…”
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Treatment of Pheochromocytoma Cells with Recurrent Cycles of Hypoxia: A New Pseudohypoxic In Vitro Model by Helm, Jana, Drukewitz, Stephan, Poser, Isabel, Richter, Susan, Friedemann, Markus, William, Doreen, Mohr, Hermine, Nölting, Svenja, Robledo, Mercedes, Bornstein, Stefan R, Eisenhofer, Graeme, Bechmann, Nicole

“…Continuous activation of hypoxia pathways in pheochromocytomas and paragangliomas (PPGLs) is associated with higher disease aggressiveness, for which effective…”
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Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo by Mohr, Hermine, Mohr, Christian A, Schneider, Marlon R, Scrivano, Laura, Adler, Barbara, Kraner-Schreiber, Simone, Schnieke, Angelika, Dahlhoff, Maik, Wolf, Eckhard, Koszinowski, Ulrich H, Ruzsics, Zsolt

“…There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of…”
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Animal models of MEN1 by Mohr, Hermine, Pellegata, Natalia S

“…Animal models of cancer have been instrumental in advancing our understanding of the biology of tumor initiation and progression, in studying gene function and…”
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Metastatic Pheochromocytoma and Paraganglioma: Somatostatin Receptor 2 Expression, Genetics, and Therapeutic Responses by Fischer, Alessa, Kloos, Simon, Maccio, Umberto, Friemel, Juliane, Remde, Hanna, Fassnacht, Martin, Pamporaki, Christina, Eisenhofer, Graeme, Timmers, Henri J L M, Robledo, Mercedes, Fliedner, Stephanie M J, Wang, Katharina, Maurer, Julian, Reul, Astrid, Zitzmann, Kathrin, Bechmann, Nicole, Žygienė, Gintarė, Richter, Susan, Hantel, Constanze, Vetter, Diana, Lehmann, Kuno, Mohr, Hermine, Pellegata, Natalia S, Ullrich, Martin, Pietzsch, Jens, Ziegler, Christian G, Bornstein, Stefan R, Kroiss, Matthias, Reincke, Martin, Pacak, Karel, Grossman, Ashley B, Beuschlein, Felix, Nölting, Svenja

“…Abstract Context Pheochromocytomas and paragangliomas (PPGLs) with pathogenic mutations in the succinate dehydrogenase subunit B (SDHB) are associated with a…”
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Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks by Delgado de la Herran, Hilda, Vecellio Reane, Denis, Cheng, Yiming, Katona, Máté, Hosp, Fabian, Greotti, Elisa, Wettmarshausen, Jennifer, Patron, Maria, Mohr, Hermine, Prudente de Mello, Natalia, Chudenkova, Margarita, Gorza, Matteo, Walia, Safal, Feng, Michael Sheng-Fu, Leimpek, Anja, Mielenz, Dirk, Pellegata, Natalia S, Langer, Thomas, Hajnóczky, György, Mann, Matthias, Murgia, Marta, Perocchi, Fabiana

“…The mitochondrial calcium uniporter channel (MCUC) mediates mitochondrial calcium entry, regulating energy metabolism and cell death. Although several MCUC…”
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ITribbles/I Genes in Gastric Cancer: A Tumor-Suppressive Role for ITRIB2/I by Foscarini, Alessia, Tricarico, Rossella, Gentile, Federica, Satam, Swapna, Mohr, Hermine, Kiss-Toth, Endre, Ranzani, Guglielmina Nadia, Pellegata, Natalia Simona

“…Tribbles pseudokinases (TRIB1-3) are important signaling modulators involved in several cancers. However, their function in gastric cancer (GC) remains…”
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miR‐34a is upregulated in AIP‐mutated somatotropinomas and promotes octreotide resistance by Bogner, Eva‐Maria, Daly, Adrian F., Gulde, Sebastian, Karhu, Auli, Irmler, Martin, Beckers, Johannes, Mohr, Hermine, Beckers, Albert, Pellegata, Natalia S.

“…Pituitary adenomas (PAs) are intracranial tumors associated with significant morbidity due to hormonal dysregulation, mass effects and have a heavy treatment…”
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Adiponectin affects the mechanical responses in strips from the mouse gastric fundus by Idrizaj, Eglantina, Garella, Rachele, Castellini, Giovanni, Mohr, Hermine, Pellegata, Natalia S, Francini, Fabio, Ricca, Valdo, Squecco, Roberta, Baccari, Maria Caterina

“…To investigate whether the adipocytes derived hormone adiponectin (ADPN) affects the mechanical responses in strips from the mouse gastric fundus. For…”
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Opposing Effects of Cannabidiol in Patient-derived Neuroendocrine Tumor, Pheochromocytoma/Paraganglioma Primary Cultures by Wang, Katharina, Schober, Laura, Fischer, Alessa, Bechmann, Nicole, Maurer, Julian, Peischer, Lea, Reul, Astrid, Hantel, Constanze, Reincke, Martin, Beuschlein, Felix, Robledo, Mercedes, Mohr, Hermine, Pellegata, Natalia S, Schilbach, Katharina, Knösel, Thomas, Ilmer, Matthias, Angele, Martin, Kroiss, Matthias, Maccio, Umberto, Broglie-Däppen, Martina, Vetter, Diana, Lehmann, Kuno, Pacak, Karel, Grossman, Ashley B, Auernhammer, Christoph J, Zitzmann, Kathrin, Nölting, Svenja

“…Abstract Context Treatment options for advanced neuroendocrine tumors (NETs), pheochromocytomas and paragangliomas (PPGLs) are still limited. In recent years,…”
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Regulation of epinephrine biosynthesis in HRAS-mutant paragangliomas by Li, Minghao, Richter, Susan, Mohr, Hermine, Drukewitz, Stephan, Poser, Isabel, Stanke, Daniela, Calsina, Bruna, Martinez-Montes, Angel M, Quinkler, Marcus, Timmers, Henri J L M, Nölting, Svenja, Beuschlein, Felix, Remde, Hanna, Opocher, Giuseppe, Rapizzi, Elena, Pacak, Karel, Pamporaki, Christina, Robledo, Mercedes, Liu, Longfei, Jiang, Jingjing, Bornstein, Stefan R, Eisenhofer, Graeme, Fliedner, Stephanie M J, Bechmann, Nicole

“…The biochemical phenotype of paragangliomas (PGLs) is highly dependent on the underlying genetic background and tumor location. PGLs at extra-adrenal locations…”
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Tribbles Genes in Gastric Cancer: A Tumor-Suppressive Role for TRIB2 by Foscarini, Alessia, Tricarico, Rossella, Gentile, Federica, Satam, Swapna, Mohr, Hermine, Kiss-Toth, Endre, Ranzani, Guglielmina Nadia, Pellegata, Natalia Simona

“…Tribbles pseudokinases (TRIB1-3) are important signaling modulators involved in several cancers. However, their function in gastric cancer (GC) remains…”
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Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study by Fischer, Alessa, Kloos, Simon, Remde, Hanna, Dischinger, Ulrich, Pamporaki, Christina, Timmers, Henri J L M, Robledo, Mercedes, Fliedner, Stephanie M J, Wang, Katharina, Maurer, Julian, Reul, Astrid, Bechmann, Nicole, Hantel, Constanze, Mohr, Hermine, Pellegata, Natalia S, Bornstein, Stefan R, Kroiss, Matthias, Auernhammer, Christoph J, Reincke, Martin, Pacak, Karel, Grossman, Ashley B, Beuschlein, Felix, Nölting, Svenja

“…Abstract Objective The therapeutic options for metastatic pheochromocytomas/paragangliomas (mPPGLs) include chemotherapy with…”
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Mutation of the Cell Cycle Regulator p27kip1 Drives Pseudohypoxic Pheochromocytoma Development by Mohr, Hermine, Ballke, Simone, Bechmann, Nicole, Gulde, Sebastian, Malekzadeh-Najafabadi, Jaber, Peitzsch, Mirko, Ntziachristos, Vasilis, Steiger, Katja, Wiedemann, Tobias, Pellegata, Natalia S

“…Pseudohypoxic tumors activate pro-oncogenic pathways typically associated with severe hypoxia even when sufficient oxygen is present, leading to highly…”
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Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response: e1003544 by Stahl, Sebastian, Burkhart, Julia M, Hinte, Florian, Tirosh, Boaz, Mohr, Hermine, Zahedi, René P, Sickmann, Albert, Ruzsics, Zsolt, Budt, Matthias, Brune, Wolfram

“…During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an…”
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