Search Results - "Mohr, Amanda L.A."
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Recommendations for Toxicological Investigation of Drug-Impaired Driving and Motor Vehicle Fatalities—2021 Update
Published in Journal of analytical toxicology (10-07-2021)“…Abstract This report describes updates to the National Safety Council’s Alcohol, Drugs and Impairment Division’s recommendations for drug testing in driving…”
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Analysis of Novel Synthetic Opioids U-47700, U-50488 and Furanyl Fentanyl by LC-MS/MS in Postmortem Casework
Published in Journal of analytical toxicology (01-11-2016)“…Following series of synthetic cannabinoid and synthetic cathinone derivatives, the illicit drug market has begun to see increased incidence of synthetic…”
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Xylazine: Pharmacology Review and Prevalence and Drug Combinations in Forensic Toxicology Casework
Published in Journal of analytical toxicology (14-10-2022)“…Abstract Xylazine, an alpha-2 receptor agonist used in veterinary medicine for its sedative and muscle-relaxant effects, has been reported in forensic…”
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Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2013–2016: A Review
Published in Journal of analytical toxicology (01-09-2017)“…Abstract Novel psychoactive substances (NPS) represent significant analytical and interpretive challenges to forensic and clinical toxicologists. Timely access…”
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Four-year evaluation of drug-impaired driving drug concentrations
Published in Journal of analytical toxicology (15-11-2024)“…Drug-impaired driving is a significant public health and safety concern in the USA. To help assess current patterns of drug use in drivers, we evaluated 4…”
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Evaluating cross-reactivity of new psychoactive substances (NPS) in human whole blood by enzyme-linked immunosorbent assay (ELISA)
Published in Journal of analytical toxicology (28-03-2024)“…Due to the increase in the use of novel psychoactive substances (NPS) and their overall prevalence, it is important to have effective and reliable screening…”
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Hide and Seek: Overcoming the Masking Effect of Opioid Antagonists in Activity-Based Screening Tests
Published in Clinical chemistry (Baltimore, Md.) (01-12-2019)“…To the Editor: We previously reported on an alternative activity-based screening method to detect (synthetic) opioids/opiates in blood samples (1) in which…”
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Evaluation of Synthetic Cannabinoid Metabolites in Human Blood in the Absence of Parent Compounds: A Stability Assessment
Published in Journal of analytical toxicology (06-02-2021)“…Abstract Synthetic cannabinoids represent a chemically diverse class of novel psychoactive substances (NPS) responsible for large analytical and interpretative…”
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N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens
Published in Journal of analytical toxicology (01-09-2018)“…N-ethyl pentylone (ephylone) has been identified as the most recent novel stimulant to emerge into the arena of evolving novel psychoactive substances (NPS)…”
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Emerging Synthetic Cannabinoids: Development and Validation of a Novel Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Assay for Real-Time Detection
Published in Journal of analytical toxicology (30-04-2020)“…Abstract Synthetic cannabinoids pose significant threats to public health and safety, as their implications in overdose and adverse events continue to arise in…”
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Activity-Based Concept to Screen Biological Matrices for Opiates and (Synthetic) Opioids
Published in Clinical chemistry (Baltimore, Md.) (01-08-2018)“…Detection of new highly potent synthetic opioids is challenging as new compounds enter the market. Here we present a novel screening method for the detection…”
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Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid, 5F-MDMB-PICA, in male rats
Published in Neuropharmacology (01-11-2021)“…5F-MDMB-PICA is a popular synthetic cannabinoid associated with analytically confirmed intoxications. In vitro studies show 5F-MDMB-PICA is a potent…”
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Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017–2020: A Review
Published in Journal of analytical toxicology (14-07-2022)“…Abstract An important role of modern forensic and clinical toxicologists is to monitor the adverse events of novel psychoactive substances (NPS). Following a…”
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Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees
Published in Forensic science international (01-01-2018)“…•The paper describes a protocol for collection of samples from a drug user population.•The paper provides a method for pharmacoepidemiological monitoring of…”
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4F‐MDMB‐BINACA: A New Synthetic Cannabinoid Widely Implicated in Forensic Casework
Published in Journal of forensic sciences (01-09-2019)“…This is the first report regarding the characterization of the new synthetic cannabinoid 4F‐MDMB‐BINACA. 4F‐MDMB‐BINACA was first analytically confirmed in…”
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A transnational perspective on the evolution of the synthetic cannabinoid receptor agonists market: Comparing prison and general populations
Published in Drug testing and analysis (01-04-2021)“…The synthetic cannabinoid receptor agonist (SCRA) market is transnational, and the availability of individual SCRAs changes regularly in response to national…”
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Analysis of the Illicit Opioid U-48800 and Related Compounds by LC–MS-MS and Case Series of Fatalities Involving U-48800
Published in Journal of analytical toxicology (14-02-2022)“…Abstract We report a method for the detection and quantitation of 12 drugs and 2 metabolites in the same structural class as the illicit mu-opioid agonist…”
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Concentrations of para-Fluorofuranylfentanyl in Paired Central and Peripheral Blood Collected during Postmortem Death Investigations
Published in Journal of analytical toxicology (21-04-2022)“…Abstract The opioid epidemic in the USA has been associated with an increasing mortality rate in large part due to the emergence and proliferation of synthetic…”
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Metabolism of novel opioid agonists U‐47700 and U‐49900 using human liver microsomes with confirmation in authentic urine specimens from drug users
Published in Drug testing and analysis (01-01-2018)“…Recently, the number of adverse events, including death, involving novel opioids has continued to increase, providing additional and sustained challenges for…”
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Evaluating Trends in Novel Psychoactive Substances Using a Sentinel Population of Electronic Dance Music Festival Attendees
Published in Journal of analytical toxicology (14-05-2021)“…Electronic dance music (EDM) festivals have become a popular venue for recreational drug use, including the use of traditional stimulants like…”
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