Search Results - "Mohler, David"

Genome-Informed Targeted Therapy for Osteosarcoma by Sayles, Leanne C, Breese, Marcus R, Koehne, Amanda L, Leung, Stanley G, Lee, Alex G, Liu, Heng-Yi, Spillinger, Aviv, Shah, Avanthi T, Tanasa, Bogdan, Straessler, Krystal, Hazard, Florette K, Spunt, Sheri L, Marina, Neyssa, Kim, Grace E, Cho, Soo-Jin, Avedian, Raffi S, Mohler, David G, Kim, Mi-Ok, DuBois, Steven G, Hawkins, Douglas S, Sweet-Cordero, E Alejandro

“…Osteosarcoma is a highly aggressive cancer for which treatment has remained essentially unchanged for more than 30 years. Osteosarcoma is characterized by…”
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An osteoinductive and biodegradable intramedullary implant accelerates bone healing and mitigates complications of bone transport in male rats by Lin, Sien, Maekawa, Hirotsugu, Moeinzadeh, Seyedsina, Lui, Elaine, Alizadeh, Hossein Vahid, Li, Jiannan, Kim, Sungwoo, Poland, Michael, Gadomski, Benjamin C., Easley, Jeremiah T., Young, Jeffrey, Gardner, Michael, Mohler, David, Maloney, William J., Yang, Yunzhi Peter

“…Bone transport is a surgery-driven procedure for the treatment of large bone defects. However, challenging complications include prolonged consolidation,…”
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Cervical erector spinae plane block catheter using a thoracic approach: an alternative to brachial plexus blockade for forequarter amputation by Tsui, Ban C. H., Mohler, David, Caruso, Thomas J., Horn, Jean Louis

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Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach by Schott, Courtney R, Koehne, Amanda L, Sayles, Leanne C, Young, Elizabeth P, Luck, Cuyler, Yu, Katherine, Lee, Alex G, Breese, Marcus R, Leung, Stanley G, Xu, Hang, Shah, Avanthi Tayi, Liu, Heng-Yi, Spillinger, Aviv, Behroozfard, Inge H, Marini, Kieren D, Dinh, Phuong T, Pons Ventura, María V, Vanderboon, Emma N, Hazard, Florette K, Cho, Soo-Jin, Avedian, Raffi S, Mohler, David G, Zimel, Melissa, Wustrack, Rosanna, Curtis, Christina, Sirota, Marina, Sweet-Cordero, E Alejandro

“…Models to study metastatic disease in rare cancers are needed to advance preclinical therapeutics and to gain insight into disease biology. Osteosarcoma is a…”
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Interactions in CSF1-Driven Tenosynovial Giant Cell Tumors by van IJzendoorn, David G P, Matusiak, Magdalena, Charville, Gregory W, Spierenburg, Geert, Varma, Sushama, Colburg, Deana R C, van de Sande, Michiel A J, van Langevelde, Kirsten, Mohler, David G, Ganjoo, Kristen N, Bui, Nam Q, Avedian, Raffi S, Bovée, Judith V M G, Steffner, Robert, West, Robert B, van de Rijn, Matt

“…A major component of cells in tenosynovial giant cell tumor (TGCT) consists of bystander macrophages responding to CSF1 that is overproduced by a small number…”
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Curettage and Cryosurgery for Low-grade Cartilage Tumors Is Associated with Low Recurrence and High Function by Mohler, David G., Chiu, Richard, McCall, David A., Avedian, Raffi S.

“…Background Chondrosarcomas of bone traditionally have been treated by wide or radical excision, procedures that may result in considerable lifelong disability…”
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Sarcoma Resection With and Without Vascular Reconstruction: A Matched Case-control Study by Poultsides, George A, Tran, Thuy B, Zambrano, Eduardo, Janson, Lucas, Mohler, David G, Mell, Matthew W, Avedian, Raffi S, Visser, Brendan C, Lee, Jason T, Ganjoo, Kristen, Harris, E John, Norton, Jeffrey A

“…OBJECTIVE:To examine the impact of major vascular resection on sarcoma resection outcomes. SUMMARY BACKGROUND DATA:En bloc resection and reconstruction of…”
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Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma by Przybyl, Joanna, Spans, Lien, Ganjoo, Kristen, Bui, Nam, Mohler, David, Norton, Jeffrey, Poultsides, George, Debiec-Rychter, Maria, van de Rijn, Matt

“…High-level amplification of MDM2 and other genes in the 12q13-15 locus is a hallmark genetic feature of well-differentiated and dedifferentiated liposarcomas…”
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Management of Patients with Newly Diagnosed Desmoid Tumors in a First-Line Setting by Testa, Stefano, Bui, Nam Q, Charville, Gregory W, Avedian, Raffi S, Steffner, Robert, Ghanouni, Pejman, Mohler, David G, Ganjoo, Kristen N

“…The initial management of desmoid tumors (DTs) is shifting from surgery towards active surveillance, with systemic and locally ablative treatments reserved for…”
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The Outcome of Patients With Localized Undifferentiated Pleomorphic Sarcoma of the Lower Extremity Treated at Stanford University by Kamat, Nikhil V, Million, Lynn, Yao, Dong-Han, Donaldson, Sarah S, Mohler, David G, van de Rijn, Matt, Avedian, Raffi S, Kapp, Daniel S, Ganjoo, Kristen N

“…As a diagnosis of exclusion, Undifferentiated Pleomorphic Sarcoma (UPS) has unclear clinical characteristics. The objective of this retrospective cohort study…”
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Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi‐institutional study by Tanaka, Kara S., Andaya, Veronica R., Thorpe, Steven W., Gundle, Kenneth R., Hayden, James B., Duong, Yee‐Cheen, Avedian, Raffi S., Mohler, David G., Morse, Lee J., Zimel, Melissa N., O'Donnell, Richard J., Fang, Andrew, Randall, Robert Lor, Tran, Tina H., New, Christin, Wustrack, Rosanna L.

“…Background Expandable endoprostheses can be used to equalize limb length for pediatric patients requiring reconstruction following large bony oncologic…”
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Patterns of Local Recurrence and Risk of Skin Recurrence in Soft Tissue Sarcomas After Surgical Resection by Ewongwo, Agnes, Oladipo, Eniola D., Hui, Caressa, Avedian, Raffi S., Steffner, Robert J., Mohler, David G., Kalbasi, Anusha, Chin, Alexander L., Million, Lynn, Hiniker, Susan M., Moding, Everett J.

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Long-term Outcomes of Diffuse or Recurrent Tenosynovial Giant Cell Tumor Treated with Postoperative External Beam Radiation Therapy by Baniel, Claire, Yoo, Christopher H., Jiang, Alice, von Eyben, Rie, Mohler, David G., Ganjoo, Kristen, Bui, Nam, Donaldson, Sarah S., Million, Lynn, van de Rijn, Matt, Oh, Justin Moon, Hiniker, Susan M.

“…Tenosynovial giant cell tumor (TGCT) is a rare proliferative disorder of synovial membrane that previously was known as pigmented villonodular synovitis…”
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Metastatic Pattern of Truncal and Extremity Leiomyosarcoma: Retrospective Analysis of Predictors, Outcomes, and Detection by Tigchelaar, Seth S, Frey, Christopher, Sivaraj, Dharshan, Segovia, Nicole A, Mohler, David G, Steffner, Robert J, Avedian, Raffi S

“…Leiomyosarcomas (LMS) are a heterogenous group of malignant mesenchymal neoplasms with smooth muscle origin and are classified as either non-uterine (NULMS) or…”
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Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy by Subramanian, Ajay, Nemat-Gorgani, Neda, Ellis-Caleo, Timothy J, van IJzendoorn, David G P, Sears, Timothy J, Somani, Anish, Luca, Bogdan A, Zhou, Maggie Y, Bradic, Martina, Torres, Ileana A, Oladipo, Eniola, New, Christin, Kenney, Deborah E, Avedian, Raffi S, Steffner, Robert J, Binkley, Michael S, Mohler, David G, Tap, William D, D'Angelo, Sandra P, van de Rijn, Matt, Ganjoo, Kristen N, Bui, Nam Q, Charville, Gregory W, Newman, Aaron M, Moding, Everett J

“…Characterization of the diverse malignant and stromal cell states that make up soft tissue sarcomas and their correlation with patient outcomes has proven…”
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Surgical Technique: Methods for Removing a Compress® Compliant Prestress Implant by Abrams, Geoffrey D., Gajendran, Varun K., Mohler, David G., Avedian, Raffi S.

“…Background The Compress® device uses a unique design using compressive forces to achieve bone ingrowth on the prosthesis. Because of its design, removal of…”
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External Beam Radiation Therapy Enhances Local Control in Pigmented Villonodular Synovitis by Horoschak, Melissa, B.S, Tran, Phuoc T., M.D., Ph.D, Bachireddy, Pavan, B.S, West, Robert B., M.D., Ph.D, Mohler, David, M.D, Beaulieu, Christopher F., M.D., Ph.D, Kapp, Daniel S., M.D., Ph.D, Donaldson, Sarah S., M.D

“…Purpose Pigmented villonodular synovitis (PVNS) is a rare proliferative disorder of the synovium with locally aggressive behavior. We reviewed our experience…”
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Extraskeletal Osteosarcoma of the Hand: The Role of Marginal Excision and Adjuvant Radiation Therapy by Casey, Dana L., van de Rijn, Matt, Riley, Geoffrey, Tung, Ka-Wah, Mohler, David G., Donaldson, Sarah S.

“…Background Extraskeletal osteosarcoma of the hand is rare, and its optimal modality of local control is not currently known. Methods A literature search was…”
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Failure of medullary tubes: A materials analysis by Taub, Marc, Wera, Glenn, Dauskardt, Reinhold H., Mohler, David G.

“…The objective of this study is to determine the effects of autoclaving on the stress, strain, ultimate tensile strength (UTS), fracture strain, modulus, and…”
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Intercalary tibial allografts following tumor resection: the role of fibular centralization by Mohler, David G, Yaszay, Burt, Hong, Richard, Wera, Glenn

“…Options to reconstruct intercalary tibial defects include allografts, vascularized bone transfers, autogenous cortical grafts, endoprostheses, and Ilizarov…”
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