Search Results - "Mohl, Jonathon"

ISOGlyP: de novo prediction of isoform-specific mucin-type O-glycosylation by Mohl, Jonathon E, Gerken, Thomas A, Leung, Ming-Ying

“…Abstract Mucin-type O-glycosylation is one of the most common posttranslational modifications of proteins. The abnormal expression of various polypeptide…”
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Assessing changes in genomic divergence following a century of human‐mediated secondary contact among wild and captive‐bred ducks by Lavretsky, Philip, McInerney, Nancy Rotzel, Mohl, Jonathon E., Brown, Joshua I., James, Helen F., McCracken, Kevin G., Fleischer, Robert C.

“…Along with manipulating habitat, the direct release of domesticated individuals into the wild is a practice used worldwide to augment wildlife populations. We…”
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RNA Post-transcriptional Modifications of an Early-Stage Large-Subunit Ribosomal Intermediate by Narayan, Gyan, Gracia Mazuca, Luis A., Cho, Samuel S., Mohl, Jonathon E., Koculi, Eda

“…Protein production by ribosomes is fundamental to life, and proper assembly of the ribosome is required for protein production. The RNA, which is…”
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Schlafen 11 Restricts Flavivirus Replication by Valdez, Federico, Salvador, Julienne, Palermo, Pedro M, Mohl, Jonathon E, Hanley, Kathryn A, Watts, Douglas, Llano, Manuel

“…Schlafen 11 (Slfn11) is an interferon-stimulated gene that controls the synthesis of proteins by regulating tRNA abundance. Likely through this mechanism,…”
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Chromosomal-level reference genome of a wild North American mallard (Anas platyrhynchos) by Lavretsky, Philip, Hernández, Flor, Swale, Thomas, Mohl, Jonathon E

“…Abstract The mallard (Anas platyrhynchos) is one of the most common, economically, and socially important birds around the world. Mallards were not only an…”
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Comparative transcriptomics of an arctic foundation species, tussock cottongrass (Eriophorum vaginatum), during an extreme heat event by Mohl, Jonathon E., Fetcher, Ned, Stunz, Elizabeth, Tang, Jianwu, Moody, Michael L.

“…Tussock cottongrass ( Eriophorum vaginatum ) is a foundation species for much of the arctic moist acidic tundra, which is currently experiencing extreme…”
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JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling by Grant, Alice H, Rodriguez, Alejandro C, Rodriguez Moncivais, Omar J, Sun, Shengjie, Li, Lin, Mohl, Jonathon E, Leung, Ming-Ying, Kirken, Robert A, Rodriguez, Georgialina

“…Overactive Janus kinases (JAKs) are known to drive leukemia, making them well-suited targets for treatment. We sought to identify new JAK-activating mutations…”
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Rapid Shift from SARS-CoV-2 Delta to Omicron Sub-Variants within a Dynamic Southern U.S. Borderplex by Robles-Escajeda, Elisa, Mohl, Jonathon E, Contreras, Lisett, Betancourt, Ana P, Mancera, Bibiana M, Kirken, Robert A, Rodriguez, Georgialina

“…COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), remains an ongoing global health challenge. This study analyzed 3641…”
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Landscape Genomics Provides Evidence of Ecotypic Adaptation and a Barrier to Gene Flow at Treeline for the Arctic Foundation Species Eriophorum vaginatum by Stunz, Elizabeth, Fetcher, Ned, Lavretsky, Philip, Mohl, Jonathon E, Tang, Jianwu, Moody, Michael L

“…Global climate change has resulted in geographic range shifts of flora and fauna at a global scale. Extreme environments, like the Arctic, are seeing some of…”
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What Makes GPCRs from Different Families Bind to the Same Ligand? by Dankwah, Kwabena Owusu, Mohl, Jonathon E., Begum, Khodeza, Leung, Ming-Ying

“…G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins with important functions in signal transduction and often serve as…”
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HIV-1 induced bystander apoptosis by Garg, Himanshu, Mohl, Jonathon, Joshi, Anjali

“…Apoptosis of uninfected bystander cells is a key element of HIV pathogenesis and believed to be the driving force behind the selective depletion of CD4+ T…”
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Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells by Campbell, Aleli, Mohl, Jonathon E, Gutierrez, Denisse A, Varela-Ramirez, Armando, Boland, Thomas

“…Bioprinting technology merges engineering and biological fields and together, they possess a great translational potential, which can tremendously impact the…”
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The meaning of wild: Genetic and adaptive consequences from large-scale releases of domestic mallards by Lavretsky, Philip, Mohl, Jonathon E., Söderquist, Pär, Kraus, Robert H. S., Schummer, Michael L., Brown, Joshua I.

“…The translocation of individuals around the world is leading to rising incidences of anthropogenic hybridization, particularly between domestic and wild…”
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Fine structure of the retrocerebral organ in the rotifer Trichocerca similis (Monogononta) by Hochberg, Rick, Araújo, Thiago Q., Walsh, Elizabeth J., Mohl, Jonathon E., Wallace, Robert L.

“…The retrocerebral organ (RCO) is a complex glandular system that is widely distributed across species of phylum Rotifera (sensu stricto). This system is…”
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GPCR-PEnDB: a database of protein sequences and derived features to facilitate prediction and classification of G protein-coupled receptors by Begum, Khodeza, Mohl, Jonathon E, Ayivor, Fredrick, Perez, Eder E, Leung, Ming-Ying

“…Abstract G protein-coupled receptors (GPCRs) constitute the largest group of membrane receptor proteins in eukaryotes. Due to their significant roles in…”
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Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways by Gutierrez, Denisse A, Contreras, Lisett, Villanueva, Paulina J, Borrego, Edgar A, Morán-Santibañez, Karla, Hess, Jessica D, DeJesus, Rebecca, Larragoity, Manuel, Betancourt, Ana P, Mohl, Jonathon E, Robles-Escajeda, Elisa, Begum, Khodeza, Roy, Sourav, Kirken, Robert A, Varela-Ramirez, Armando, Aguilera, Renato J

“…In this study, we identified a novel pyrazole-based derivative (P3C) that displayed potent cytotoxicity against 27 human cancer cell lines derived from…”
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Human macrophage polarization in the response to Mycobacterium leprae genomic DNA by Marin, Alberto, Van Huss, Kristopher, Corbett, John, Kim, Sangjin, Mohl, Jonathon, Hong, Bo-young, Cervantes, Jorge

“…•The established thinking is that host response, rather than M. leprae strain variation, is the reason for the broad variation of symptoms in the leprosy…”
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Understanding the binding of the same ligand to GPCRs of different families by Dankwah, Kwabena Owusu, Mohl, Jonathon E, Begum, Khodeza, Leung, Ming-Ying

“…G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins with important functions in signal transduction and often serve as…”
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Abstract 2123 Systematic characterizations of modifications and RNA processing in ribosome assembly via direct RNA sequencing by Weislow, Isaac, Mazuca, Luis Gracia, Rodarte, Salvador, Beltran, Davor, Mohl, Jonathon, Koculi, Eda

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The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border by Grant, Alice Hernandez, Ayala-Marin, Yoshira Marie, Mohl, Jonathon Edward, Robles-Escajeda, Elisa, Rodriguez, Georgialina, Dutil, Julie, Kirken, Robert Arthur

“…Next-generation sequencing (NGS) has identified unique biomarkers yielding new strategies in precision medicine for the treatment of Acute lymphoblastic…”
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