Search Results - "Mohd Yusof, Adlina"
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A Novel Dual AMPK Activator/mTOR Inhibitor Inhibits Thyroid Cancer Cell Growth
Published in The journal of clinical endocrinology and metabolism (01-05-2015)“…Context: Activated AMP protein kinase (AMPK) is a key regulator of intracellular energy homeostasis and may also function as a tumor suppressor by inhibiting…”
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RCAN1-4 is a thyroid cancer growth and metastasis suppressor
Published in JCI insight (09-03-2017)“…Metastasis suppressors are key regulators of tumor growth, invasion, and metastases. Loss of metastasis suppressors has been associated with aggressive tumor…”
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Development of a calcium-sensing receptor molecular imaging agent
Published in Surgery (01-12-2013)“…Background Calcium-sensing receptor (CaSR) is expressed by parathyroid cells and thyroid C-cells (from which medullary thyroid carcinoma [MTC] is derived). A…”
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The Crystal Structure of Calcium-bound Annexin Gh1 from Gossypium hirsutum and Its Implications for Membrane Binding Mechanisms of Plant Annexins
Published in The Journal of biological chemistry (27-06-2008)“…Plant annexins show distinct differences in comparison with their animal orthologues. In particular, the endonexin sequence, which is responsible for…”
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Structural evidence for variable oligomerization of the N-terminal domain of cyclase-associated protein (CAP)
Published in Proteins, structure, function, and bioinformatics (01-02-2005)“…Cyclase‐associated protein (CAP) is a highly conserved and widely distributed protein that links the nutritional response signaling to cytoskeleton remodeling…”
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Mechanism of Oligomerisation of Cyclase-associated Protein from Dictyostelium discoideum in Solution
Published in Journal of molecular biology (06-10-2006)“…Cyclase-associated protein (CAP) is a highly conserved modular protein implicated in the regulation of actin filament dynamics and a variety of developmental…”
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Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly
Published in Molecular biology of the cell (15-12-2010)“…The nondegradable Mps1(Δ12/13) protein drives centriole overproduction, suggesting that Mps1 phosphorylates a subset of centrosomal proteins to drive the…”
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Preventing the degradation of mps1 at centrosomes is sufficient to cause centrosome reduplication in human cells
Published in Molecular biology of the cell (01-11-2007)“…Supernumerary centrosomes promote the assembly of abnormal mitotic spindles in many human tumors. In human cells, overexpression of the cyclin-dependent kinase…”
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Localization of CaSR Antagonists in CaSR-expressing Medullary Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (01-11-2013)“…Objective: Image-based localization of medullary thyroid cancer (MTC) and parathyroid glands would improve the surgical outcomes of these diseases. MTC and…”
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10
Structural Determinants for Plant Annexin−Membrane Interactions
Published in Biochemistry (Easton) (13-12-2005)“…The interactions of two plant annexins, annexin 24(Ca32) from Capsicum annuum and annexin Gh1 from Gossypium hirsutum, with phospholipid membranes have been…”
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