Search Results - "Mohawk, Jennifer A"

Central and Peripheral Circadian Clocks in Mammals by MOHAWK, Jennifer A, GREEN, Carla B, TAKAHASHI, Joseph S

“…The circadian system of mammals is composed of a hierarchy of oscillators that function at the cellular, tissue, and systems levels. A common molecular…”
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Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm by Yoo, Seung-Hee, Mohawk, Jennifer A., Siepka, Sandra M., Shan, Yongli, Huh, Seong Kwon, Hong, Hee-Kyung, Kornblum, Izabela, Kumar, Vivek, Koike, Nobuya, Xu, Ming, Nussbaum, Justin, Liu, Xinran, Chen, Zheng, Chen, Zhijian J., Green, Carla B., Takahashi, Joseph S.

“…Period determination in the mammalian circadian clock involves the turnover rate of the repressors CRY and PER. We show that CRY ubiquitination engages two…”
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Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators by Mohawk, Jennifer A, Takahashi, Joseph S

“…The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of the master circadian pacemaker in mammals. The individual cells of the SCN are capable of…”
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Glucocorticoids as Entraining Signals for Peripheral Circadian Oscillators by Pezük, Pınar, Mohawk, Jennifer A, Wang, Laura A, Menaker, Michael

“…Mammalian circadian organization is governed by pacemaker neurons in the brain that communicate with oscillators in peripheral tissues. Adrenal glucocorticoids…”
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Notalgia Paresthetica Dermatologist Report of Symptom Burden and Treatment: Results from a Physician Survey by Kim, Brian S., Ständer, Sonja, Kabashima, Kenji, Mohawk, Jennifer A., So, Sherri, Goncalves, Joana, Shah, Nilam, Munera, Catherine, Punzalan, Joseph C., Argudo, Romelia, Lebwohl, Mark

“…Notalgia paresthetica (NP) is a sensory neuropathy characterized by chronic pruritus, skin pain, and other pathologic sensations affecting the mid-to-upper…”
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Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice by Mohawk, Jennifer A, Cox, Kimberly H, Sato, Makito, Yoo, Seung-Hee, Yanagisawa, Masashi, Olson, Eric N, Takahashi, Joseph S

“…The transcription factor, myocyte enhancer factor-2 (MEF2), is required for normal circadian behavior in ; however, its role in the mammalian circadian system…”
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Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE) by Kim, Brian S, Mohawk, Jennifer A, So, Sherri, Cirulli, Joshua, Goncalves, Joana, Punzalan, Joseph C, Lebwohl, Mark

“…Notalgia paresthetica (NP) is a form of neuropathic itch characterized by recurrent itch in the mid back. Much about NP remains unclear, especially the patient…”
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Methamphetamine and dopamine receptor D1 regulate entrainment of murine circadian oscillators by Mohawk, Jennifer A, Pezuk, Pinar, Menaker, Michael

“…We investigated the effect of methamphetamine (MA) injections on the circadian organization of behavior and individual tissues in the mouse. Scheduled, daily…”
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methamphetamine-sensitive circadian oscillator does not employ canonical clock genes by Mohawk, Jennifer A, Baer, Matthew L, Menaker, Michael

“…The "master clock" in the suprachiasmatic nucleus (SCN) of the hypothalamus controls most behavioral, physiological, and molecular circadian rhythms in…”
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Circadian Organization Is Governed by Extra-SCN Pacemakers by Pezuk, Pinar, Mohawk, Jennifer A., Yoshikawa, Tomoko, Sellix, Michael T., Menaker, Michael

“…In mammals, a pacemaker in the suprachiasmatic nucleus (SCN) is thought to be required for behavioral, physiological, and molecular circadian rhythms. However,…”
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HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections by Sun, Lei, Jiang, Zhengfan, Acosta-Rodriguez, Victoria A, Berger, Michael, Du, Xin, Choi, Jin Huk, Wang, Jianhui, Wang, Kuan-Wen, Kilaru, Gokhul K, Mohawk, Jennifer A, Quan, Jiexia, Scott, Lindsay, Hildebrand, Sara, Li, Xiaohong, Tang, Miao, Zhan, Xiaoming, Murray, Anne R, La Vine, Diantha, Moresco, Eva Marie Y, Takahashi, Joseph S, Beutler, Bruce

“…Transcriptional regulation of numerous interferon-regulated genes, including ( ), which encodes an innate immune sensor of viral double-stranded RNA, depends…”
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Circadian dependence of corticosterone release to light exposure in the rat by Mohawk, Jennifer A, Pargament, Jonathan M, Lee, Theresa M

“…Abstract Previous studies have demonstrated a positive correlation between glucocorticoid levels and circadian reentrainment time following a shift in the…”
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A new (and different) circadian pacemaker by Mohawk, Jennifer A., Menaker, Michael

“…Comment on: Mohawk JA, Baer ML, Menaker M. The methamphetamine-sensitive circadian oscillator does not employ canonical clock genes. Proc Natl Acad Sci U S A…”
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Inhibiting cortisol response accelerates recovery from a photic phase shift by Mohawk, Jennifer A, Cashen, Katherine, Lee, Theresa M

“…Jetlag results when a temporary loss of circadian entrainment alters phase relationships among internal rhythms and between an organism and the outside world…”
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Burden of Disease and Unmet Needs in Atopic Dermatitis: Results From a Patient Survey by Silverberg, Jonathan I, Mohawk, Jennifer A, Cirulli, Joshua, Nograles, Kristine, Punzalan, Joseph C, Kelly, Kevin M, Kim, Brian S, Guttman-Yassky, Emma, Lebwohl, Mark

“…Atopic dermatitis (AD) affects 2%-10% of adults worldwide. Occurrence and severity of symptoms and treatment success vary among patients. To determine disease…”
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Restraint Stress Delays Reentrainment in Male and Female Diurnal and Nocturnal Rodents by Mohawk, Jennifer A., Lee, Theresa M.

“…Atemporary loss of normal circadian entrainment, such as that associated with shift work and transmeridian travel, can result in an array of detrimental…”
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A novel mutation in Slc2a4 as a mouse model of fatigue by Groot, Marleen H. M., Castorena, Carlos M., Cox, Kimberly H., Kumar, Vivek, Mohawk, Jennifer A., Ahmed, Newaz I., Takahashi, Joseph S.

“…Chronic fatigue is a debilitating disorder with widespread consequences, but effective treatment strategies are lacking. Novel genetic mouse models of fatigue…”
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Lithium and genetic inhibition of GSK3β enhance the effect of methamphetamine on circadian rhythms in the mouse by Mohawk, Jennifer A, Miranda-Anaya, Manuel, Tataroglu, Ozgur, Menaker, Michael

“…Lithium, a drug commonly used to treat mood disorders, and the psychostimulant methamphetamine are both capable of altering circadian rhythmicity. Although the…”
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Beyond the suprachiasmatic nucleus: Other circadian clocks in the brain by Mohawk, Jennifer A., Menaker, Michael

“…While the suprachiasmatic nucleus (SCN) is considered the "master pacemaker" governing mammalian circadian rhythms, there is substantial evidence for a…”
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Symptoms of Neuropathic Itch: A Report From the Neuropathic Itch Patient Survey (NIRVE) by Kim, Brian S., Mohawk, Jennifer A., Cirulli, Joshua, Goncalves, Joana, Punzalan, Joseph C., Kelly, Kevin M., Lebwohl, Mark

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