Search Results - "Mohanram, Harini"

Resurrecting Inactive Antimicrobial Peptides from the Lipopolysaccharide Trap by MOHANRAM, Harini, BHATTACHARJYA, Surajit

“…Host defense antimicrobial peptides (AMPs) are a promising source of antibiotics for the treatment of multiple-drug-resistant pathogens. Lipopolysaccharide…”
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Lipopolysaccharide Neutralizing Peptide–Porphyrin Conjugates for Effective Photoinactivation and Intracellular Imaging of Gram-Negative Bacteria Strains by Liu, Fang, Soh Yan Ni, Annie, Lim, Yingjie, Mohanram, Harini, Bhattacharjya, S, Xing, Bengang

“…A simple and specific strategy based on the bioconjugation of a photosensitizer protophophyrin IX (PpIX) with a lipopolysaccharide (LPS) binding antimicrobial…”
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NMR structure of temporin-1 ta in lipopolysaccharide micelles: mechanistic insight into inactivation by outer membrane by Saravanan, Rathi, Joshi, Mangesh, Mohanram, Harini, Bhunia, Anirban, Mangoni, Maria Luisa, Bhattacharjya, Surajit

“…Antimicrobial peptides (AMPs) play important roles in the innate defense mechanism. The broad spectrum of activity of AMPs requires an efficient…”
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β-Boomerang Antimicrobial and Antiendotoxic Peptides: Lipidation and Disulfide Bond Effects on Activity and Structure by Mohanram, Harini, Bhattacharjya, Surajit

“…Drug-resistant Gram-negative bacterial pathogens and endotoxin- or lipopolysaccharide (LPS)-mediated inflammations are among some of the most  prominent health…”
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Lipopolysaccharide bound structures of the active fragments of fowlicidin-1, a cathelicidin family of antimicrobial and antiendotoxic peptide from chicken, determined by transferred nuclear overhauser effect spectroscopy by Bhunia, Anirban, Mohanram, Harini, Bhattacharjya, Surajit

“…Cathelicidins comprise a major family of host‐defense antimicrobial peptides in vertebrates. The C‐terminal part of the cathelicidins is bestowed with…”
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A Short Peptide Hydrogel with High Stiffness Induced by 310‐Helices to β‐Sheet Transition in Water by Hiew, Shu Hui, Mohanram, Harini, Ning, Lulu, Guo, Jingjing, Sánchez‐Ferrer, Antoni, Shi, Xiangyan, Pervushin, Konstantin, Mu, Yuguang, Mezzenga, Raffaele, Miserez, Ali

“…Biological gels generally require polymeric chains that produce long‐lived physical entanglements. Low molecular weight colloids offer an alternative to…”
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Accelerated corrosion of marine-grade steel by a redox-active, cysteine-rich barnacle cement protein by Murugan, Vinod K., Mohanram, Harini, Budanovic, Maja, Latchou, Arvind, Webster, Richard David, Miserez, Ali, Seita, Matteo

“…A serious consequence of marine biofouling on metallic structures is the insidious localized corrosion at the attachment sites of fouling organisms, such as…”
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Fast and Green Synthesis of an Oligo-Hydrocaffeic Acid-Based Adhesive by Ghadban, Ali, Mohanram, Harini, Miserez, Ali

“…A green, mussel-inspired bioadhesive based on oligomerization of hydrocaffeic acid was synthesized in water by an ultrafast one-step reaction in the presence…”
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Release of frustration drives corneal amyloid disaggregation by brain chaperone by Low, Jia Yi Kimberly, Shi, Xiangyan, Anandalakshmi, Venkatraman, Neo, Dawn, Peh, Gary Swee Lim, Koh, Siew Kwan, Zhou, Lei, Abdul Rahim, M. K., Boo, Ketti, Lee, JiaXuan, Mohanram, Harini, Alag, Reema, Mu, Yuguang, Mehta, Jodhbir S., Pervushin, Konstantin

“…TGFBI-related corneal dystrophy (CD) is characterized by the accumulation of insoluble protein deposits in the corneal tissues, eventually leading to…”
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NMR structural studies of the Ste11 SAM domain in the dodecyl phosphocholine micelle by Bhunia, Anirban, Domadia, Prerna N., Mohanram, Harini, Bhattacharjya, Surajit

“…The sterile α‐motif (SAM), a relatively small (∼70 amino acids) interaction domain, is found in a variety of proteins involved in cell signaling, transcription…”
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Salt-resistant short antimicrobial peptides by Mohanram, Harini, Bhattacharjya, Surajit

“…ABSTRACT Antimicrobial peptides (AMPs) are promising leads for the development of antibiotics against drug resistant bacterial pathogens. However, in vivo…”
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Liquid–Liquid Phase Separation of the Green Mussel Adhesive Protein Pvfp‐5 is Regulated by the Post‐Translated Dopa Amino Acid by Deepankumar, Kanagavel, Guo, Qi, Mohanram, Harini, Lim, Jessica, Mu, Yuguang, Pervushin, Konstantin, Yu, Jing, Miserez, Ali

“…The underwater adhesive prowess of aquatic mussels has been largely attributed to the abundant post‐translationally modified amino acid…”
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‘Lollipop’-shaped helical structure of a hybrid antimicrobial peptide of temporin B-lipopolysaccharide binding motif and mapping cationic residues in antibacterial activity by Mohanram, Harini, Bhattacharjya, Surajit

“…Temporins are attractive templates for the development of antibiotics. However, many temporins are inactive against Gram-negative bacteria. Previously, we…”
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Cysteine deleted protegrin-1 (CDP-1): Anti-bacterial activity, outer-membrane disruption and selectivity by Mohanram, Harini, Bhattacharjya, Surajit

“…Protegin-1 (PG-1: RGGRLCYCRRRFCVCVGR-amide) assumes a rigid β-hairpin like structure that is stabilized by two disulfide bridges between Cys6–Cys15 and…”
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Self-Assembly of a Barnacle Cement Protein (MrCP20) into Adhesive Nanofibrils with Concomitant Regulation of CaCO 3 Polymorphism by Mohanram, Harini, Georges, Tristan, Pervushin, Konstantin, Azaïs, Thierry, Miserez, Ali

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Self-Assembly of a Barnacle Cement Protein (MrCP20) into Adhesive Nanofibrils with Concomitant Regulation of CaCO3 Polymorphism by Mohanram, Harini, Georges, Tristan, Pervushin, Konstantin, Azaïs, Thierry, Miserez, Ali

“…Barnacles are convenient model organisms to study both biomineralization and bioadhesion phenomena. They secrete a proteinaceous adhesive from cement proteins…”
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Three-dimensional structure of Megabalanus rosa Cement Protein 20 revealed by multi-dimensional NMR and molecular dynamics simulations by Mohanram, Harini, Kumar, Akshita, Verma, Chandra S, Pervushin, Konstantin, Miserez, Ali

“…Barnacles employ a protein-based cement to firmly attach to immersed substrates. The cement proteins (CPs) have previously been identified and sequenced…”
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Self-assembly of peptide nanocapsules by a solvent concentration gradient by Li, Haopeng, Qian, Xuliang, Mohanram, Harini, Han, Xiao, Qi, Huitang, Zou, Guijin, Yuan, Fenghou, Miserez, Ali, Liu, Tian, Yang, Qing, Gao, Huajian, Yu, Jing

“…Biological systems can create materials with intricate structures and specialized functions. In comparison, precise control of structures in human-made…”
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Disorder–Order Interplay of a Barnacle Cement Protein Triggered by Interactions with Calcium and Carbonate Ions: A Molecular Dynamics Study by Kumar, Akshita, Mohanram, Harini, Li, Jianguo, Le Ferrand, Hortense, Verma, Chandra S, Miserez, Ali

“…Barnacles strongly adhere to immersed solid substrates using a mixture of cement proteins (CP) that self-assembles into a permanently bonded layer and binds…”
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Structure of a consensus chitin-binding domain revealed by solution NMR by Heymann, Dario, Mohanram, Harini, Kumar, Akshita, Verma, Chandra S., Lescar, Julien, Miserez, Ali

“…[Display omitted] •Using solution NMR, we have studied molecular-level interactions between a chitin-binding domain (CBD) containing the consensus…”
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