Search Results - "Mohan, Mradul"

Exploring links between vitamin D deficiency and COVID-19 by Mohan, Mradul, Cherian, Jerin Jose, Sharma, Amit

“…Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome…”
Get full text

Time to implement tailored interventions in Chhattisgarh, east-central India to reach malaria elimination by Ranjha, Ritesh, Sontee, Yadav, Chander Prakash, Mohan, Mradul, Singh, Kuldeep, Kumar, Jitendra, Bharti, Praveen Kumar, Anvikar, Anup R

“…Despite significant progress in malaria control throughout India, Chhattisgarh state continues to be a significant contributor to both malaria morbidity and…”
Get full text

Profiles of host immune impairment in Plasmodium and SARS-CoV-2 infections by Chaturvedi, Rini, Mohan, Mradul, Kumar, Sanjeev, Chandele, Anmol, Sharma, Amit

“…Over the past two decades, many countries have reported a steady decline in reported cases of malaria, and a few countries, like China, have been declared…”
Get full text

Association of the C allele of rs479200 in the EGLN1 gene with COVID-19 severity in Indian population: a novel finding by Harit, Renuka, De, Sajal, Singh, Piyoosh Kumar, Kashyap, Deepika, Kumar, Manish, Sahu, Dibakar, Yadav, Chander Prakash, Mohan, Mradul, Singh, Vineeta, Tomar, Ram Singh, Pandey, Kailash C, Vashisht, Kapil

“…The present study investigated two single nucleotide polymorphisms (SNPs)-rs479200 and rs516651 in the host EGLN1/PHD2 gene for their association with COVID-19…”
Get full text

Correction: Association of the C allele of rs479200 in the EGLN1 gene with COVID-19 severity in Indian population: a novel finding by Harit, Renuka, De, Sajal, Singh, Piyoosh Kumar, Kashyap, Deepika, Kumar, Manish, Sahu, Dibakar, Yadav, Chander Prakash, Mohan, Mradul, Singh, Vineeta, Tomar, Ram Singh, Pandey, Kailash C, Vashisht, Kapil

Get full text

Rethinking malaria vaccines: perspectives on currently approved malaria vaccines in India’s path to elimination by Ranjha, Ritesh, Bai, Priyanka, Singh, Kuldeep, Mohan, Mradul, Bharti, Praveen K, Anvikar, Anup R

“…Introduction Malaria, a longstanding and life-threatening disease, contributes to approximately 249 million global cases.1 Plasmodium falciparum, among the…”
Get full text

Inhaled Microparticles Containing Clofazimine Are Efficacious in Treatment of Experimental Tuberculosis in Mice by Verma, Rahul Kumar, Germishuizen, Willem A, Motheo, M Portia, Agrawal, Atul Kumar, Singh, Amit Kumar, Mohan, Mradul, Gupta, Pushpa, Gupta, Umesh Datta, Cholo, Moloko, Anderson, Ronald, Fourie, P Bernard, Misra, Amit

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Age-specific malaria vulnerability and transmission reservoir among children by Ranjha, Ritesh, Singh, Kuldeep, Mohan, Mradul, Anvikar, Anup R, Bharti, Praveen K.

“…The pediatric population, especially under-five children, is highly susceptible to malaria and accounts for 76 % of global malaria deaths according to the…”
Get full text

Challenges with Mosquito-borne Viral Diseases: Outbreak of the Monsters by Gautam, Renu, Mishra, Sweta, Milhotra, Archana, Nagpal, Ritika, Mohan, Mradul, Singhal, Anchal, Kumari, Pratibha

“…The viruses responsible for mosquito-borne diseases are on an exploring mode, expanding their horizon, adapting to the situation and comfortably making their…”
Get more information

Correction: Exploring links between vitamin D deficiency and COVID-19 by Mradul Mohan, Jerin Jose Cherian, Amit Sharma

“…[This corrects the article DOI: 10.1371/journal.ppat.1008874.]…”
Get full text

Effects of Host Genetic Polymorphisms on the Efficacy of the Radical Cure Malaria Drug Primaquine by Nain, Minu, Mohan, Mradul, Sharma, Amit

“…Malaria is a major cause of death in low-income countries. Malaria relapses are caused by Plasmodium vivax-induced latent liver stage hypnozoites, and relapses…”
Get full text

Single-Nucleotide Polymorphisms in Glucose-6-Phosphate Dehydrogenase and their Relevance for the Deployment of Primaquine as a Radical Cure for Malaria by Nain, Minu, Gill, Jasmita, Mohan, Mradul, Sharma, Amit

“…Malaria remains an important public health problem despite efforts to control it. Besides active transmission, relapsing malaria caused by dormant liver stages…”
Get full text

Inhalable particles containing isoniazid and rifabutin as adjunct therapy for safe, efficacious and relapse-free cure of experimental animal tuberculosis in one month by Singh, Amit K., Verma, Rahul K., Mukker, Jatinder Kaur, Yadav, Awadh B., Muttil, Pavan, Sharma, Rolee, Mohan, Mradul, Agrawal, Atul K., Gupta, Anuradha, Dwivedi, Anil K., Gupta, Pushpa, Gupta, Umesh D., Mani, Uthirappan, Chaudhari, Bhushan P., Murthy, Ramesh C., Sharma, Sharad, Bhadauria, Smrati, Singh, Sarika, Rath, Srikanta Kumar, Misra, Amit

“…We investigated the preclinical efficacy and safety/tolerability of biodegradable polymeric particles containing isoniazid (INH) and rifabutin (RFB) dry powder…”
Get full text

Inhalable microparticles of nitric oxide donors induce phagosome maturation and kill Mycobacterium tuberculosis by Verma, Rahul Kumar, Agrawal, Atul Kumar, Singh, Amit Kumar, Mohan, Mradul, Gupta, Anuradha, Gupta, Pushpa, Gupta, Umesh Datta, Misra, Amit

“…Summary Nitric oxide (NO) kills Mycobacterium tuberculosis (Mtb) in vitro , but gaseous NO is difficult to administer to patients. We evaluated the…”
Get full text

Inhalable Microparticles Containing Nitric Oxide Donors: Saying NO to Intracellular Mycobacterium tuberculosis by Verma, Rahul K, Singh, Amit K, Mohan, Mradul, Agrawal, Atul K, Verma, Priya R. P, Gupta, Anuradha, Misra, Amit

“…Although nitric oxide (NO) is a bactericidal component of the macrophage’s innate response to intracellular infections such as tuberculosis (TB), prolonged…”
Get full text

Particulate pulmonary delivery systems containing anti-tuberculosis agents by Gupta, Anuradha, Pandya, Sanketkumar M, Mohammad, Imran, Agrawal, Atul Kumar, Mohan, Mradul, Misra, Amit

“…There is renewed interest in delivering anti-tuberculosis (TB) drugs to the lungs by inhalation. Several groups have investigated particulate pulmonary drug…”
Get more information

Inhalable microparticles containing isoniazid and rifabutin target macrophages and 'stimulate the phagocyte' to achieve high efficacy by Yadav, Awadh Bihari, Sharma, Rolee, Muttil, Pavan, Singh, Amit Kumar, Verma, Rahul Kumar, Mohan, Mradul, Patel, Sanjay Kumar, Misra, Amit

“…Macrophage responses to infection with Mycobacterium tuberculosis (MTB) and treatment with soluble isoniazid (INH) plus rifabutin (RFB) versus microparticles…”
Get full text

The devil’s advocacy: When and why inhaled therapies for tuberculosis may not work by Yadav, Awadh Bihari, Singh, Amit K, Verma, Rahul K, Mohan, Mradul, Agrawal, Atul K, Misra, Amit

“…Summary Factors that are inimical to the success of inhaled therapies for tuberculosis (TB) include: (i) lack of access of inhaled therapies to poorly-aerated…”
Get full text

Inhaled therapies for tuberculosis and the relevance of activation of lung macrophages by particulate drug-delivery systems by Verma, Rahul Kumar, Singh, Amit Kumar, Mohan, Mradul, Agrawal, Atul Kumar, Misra, Amit

“…Pathogenic strains of Mycobacterium tuberculosis (Mtb) induce 'alternative activation' of lung macrophages that they colonize, in order to create conditions…”
Get more information

Microparticles induce variable levels of activation in macrophages infected with Mycobacterium tuberculosis by Yadav, Awadh B, Muttil, Pavan, Singh, Amit K, Verma, Rahul K, Mohan, Mradul, Agrawal, Atul K, Verma, Ajay S, Sinha, Sudhir K, Misra, Amit

“…Summary Activation of human macrophages infected with Mycobacterium tuberculosis was investigated following exposure to microparticles (MP) possessing high…”
Get full text