Search Results - "Mohammed, Zainuddin"

Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer by Gajendran, Chandru, Tantry, Subramanyam Janardhan, M, Naveen Sadhu, Mohammed, Zainuddin, Dewang, Purushottam, Hallur, Mahanandeesha, Nair, Sreekala, Vaithilingam, Krishnakumar, Nagayya, Basavaprabhu, Rajagopal, Sridharan, Sivanandhan, Dhanalakshmi

“…Dually targeting the epigenetic proteins lysine specific demethylase 1 (LSD1) and histone deacetylases (HDACs) that play a key role in cancer cells by…”
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Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4 by Gajendran, Chandru, Fukui, Shoichi, Sadhu, Naveen M., Zainuddin, Mohammed, Rajagopal, Sridharan, Gosu, Ramachandraiah, Gutch, Sarah, Fukui, Saeko, Sheehy, Casey E., Chu, Long, Vishwakarma, Santosh, Jeyaraj, D. A., Hallur, Gurulingappa, Wagner, Denisa D., Sivanandhan, Dhanalakshmi

“…Protein arginine deiminases (PAD) 4 is an enzyme that catalyzes citrullination of protein and its role in autoimmune diseases has been established through…”
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Abstract 1630: Novel, small molecule inhibitors of PD-L1/PD-1 interaction by Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, M, Naveen Sadhu, Gajendran, Chandru, venkateshappa, Chandregowda, Reddy, Muralidhar, Kishore, Pendyala Satya, Deshpande, Pratima, kannan, Sundarajan, Sahareen, Tabassum, Viswakarma, Santhosh, Siddiqui, Amir, Zainuddin, Mohammed, G, Rudresh, Daram, Prashanthi, Gosu, Ramchandraiah, Devi, Rashmi Rekha

“…Introduction: The PD-1/PD-L1 molecular pathway is one of the primary mechanisms of immune evasion deployed by cancer cells. Induction of PD-L1 expression on…”
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Abstract 1128: Selective, novel, small molecule PRMT5 inhibitors for treatment of cancer by Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, M, Naveen Sadhu, Gajendran, Chandru, Vadivelu, Saravanan, Tamizharasan, Natarajan, Swamy, Indu N., Viswakarma, Santhosh, Siddiqui, Amir, wahid, Saif, Zainuddin, Mohammed, G, Rudresh, Daram, Prashanthi, Gosu, Ramchandraiah, Tiagaraj, Dinesh, Garapaty, Shivani, Nair, Sreekala, Kapoor, Namratha

“…Introduction: Arginine methylation deregulation in cancer has been well studied and PRMT5 which modulates dimethylation of arginine has emerged as an…”
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1386 Novel gut-restricted small molecule inhibitor of PD-L1 for targeting GI cancers by Sivanandhan, Dhanalakshmi, Sridharan Rajagopal, Gajendran, Chandru, Naveen, Sadhu M, Zainuddin, Mohammed, Ramachandraiah Gosu, Rastelli, Luca

“…BackgroundThe PD-1/PD-L1 molecular pathway is one of the primary mechanisms of immune evasion deployed by cancer cells and several anti-PD-L1 monoclonal…”
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A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease by Kalindjian, S. Barret, Kadnur, Sanjay V, Hewson, Christopher A, Venkateshappa, Chandregowda, Juluri, Suresh, Kristam, Rajendra, Kulkarni, Bheemashankar, Mohammed, Zainuddin, Saxena, Rohit, Viswanadhan, Vellarkad N, Aiyar, Jayashree, McVey, Donna

“…Chemokine receptor 9 (CCR9), a cell surface chemokine receptor which belongs to the G protein-coupled receptor, 7-trans-membrane superfamily, is expressed on…”
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Abstract 6269: JBI-778, a novel brain-penetrant small molecule PRMT5 inhibitor for treatment of cancer by Sivanandhan, Dhanalakshmi, Gajendran, Chandru, M, Naveen Sadhu, Mohammed, Zainuddin, Gosu, Ramachandraiah, Sher, Divsha, Mansur, Shahar, Friedmann-Morvinski, Dinorah, Rajagopal, Sridharan, Rastelli, Luca

“…Introduction: Protein arginine methyltransferases (PRMTs) transfer a methyl group from the cofactor S-adenosyl-L-methionine (SAM) to the arginine of a…”
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